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Questions tagged [genetics]

Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.

3 votes
1 answer
75 views

Post-Translational Modification in insulin production

When searching "How is insulin produced commercially" on Google, most results simply say something along the lines of "The insulin gene is inserted into a bacteria, which then express ...
user73910's user avatar
  • 439
0 votes
0 answers
21 views

What backbone to use for Helper dependent adenovirus (HDAd)

I have been trying to design a plasmid for a helper dependent adenovirus but while looking i wasn't able to see a backbone specifically for HDAds so I was wondering if a general adenovirus backbone ...
Gpgabriel25's user avatar
3 votes
0 answers
16 views

How to model the relationship between environments based on environmental covariates in a genomic prediction context

I have a dataset with different wheat lines in multiple environments. For each line various traits are measured (e.g. grain yield). I am trying to set up various genomic prediction models (linear ...
set_user123's user avatar
0 votes
0 answers
22 views

Is it possible to improve metabolic rate through quorum sensing?

I am building a microbial fuel cell unit using mint plant and soil microbes. My goal is to power a LED light using the electricity but the electrify that microbes are so little so I am thinking of ...
jia's user avatar
  • 1
2 votes
0 answers
34 views

How to understand restriction mapping a quarter of a century later?

Today, biology is virtually all based on massively parallel sequencing, long-strand sequencing, and metagenomic; looking back at old restriction mapping is not straightforward (at least for me). For ...
Gigiux's user avatar
  • 673
0 votes
1 answer
60 views

Mechanism of random assortment of chromosomes

How does the random assortment of chromosomes during meiosis occur? I am a mathematician, not a biologist, and I am surprised that it is difficult to find an answer to this question online (AI ...
Lawrence Fields's user avatar
1 vote
1 answer
48 views

About tomatoes pigments, why red tomatoes rather than yellow ones

How the first tomatoes (yellow) that arrived in Europe turned from yellow to red ? I know the yellow pigment is xantophylle and the red one is lycopene, but my question is, was it an adaptation of the ...
Quidam's user avatar
  • 151
5 votes
3 answers
123 views

What has caused my oxeye daisies to mutate?

Some oxeye daisies (Leucanthemum vulgare) in my garden are showing strange mutations. I have a few oxeye daisy plants around my garden in different areas, but only one plant's flowers are showing ...
cerys's user avatar
  • 51
1 vote
3 answers
83 views

Can phenotype change without change in genotype?

If a person with lighter skin is to live in areas close to the equator for a long amount of time, their skin would get darker, and hence their phenotype gets 'altered'. If I'm to look at their gene ...
Mel's user avatar
  • 13
0 votes
0 answers
72 views

What is a reference strain in DNA-DNA hybridization DNA groups?

Results DNA groups identified: All intra-group relatedness values are shown in Table I. By means of reference strains, most of the DNA groups could be identified as groups described by Bouvet & ...
Freezing Soul's user avatar
2 votes
2 answers
56 views

How would you find out which gene is causing a specific phenotype in Drosophila through crosses only?

I'd recently attended an interview and was asked a question I've been trying to get to the bottom of. The question was that there is a mutation in which some smaller drosophila are only attracted to ...
Ananya Katikeneni's user avatar
0 votes
1 answer
26 views

identification of most Active gene/protein isoform

I am investigating a gene, and on ensemble, it has multiple variants. How can i know which gene or protein isoform is most active?
qwerty's user avatar
  • 1
0 votes
0 answers
22 views

Limma - Voom function for microarray data

I am wondering if anyone can have a look at the voom plot I got below and let me know if this is indicative of an issue with my design? I understand that it should be more of a J-shape rather than a ...
Sachin Rahul's user avatar
7 votes
1 answer
785 views

Are there any completely, or 'true', Mendelian traits that do not display any polygeny at all?

Recently, I learned about polygenic traits and it got me wondering, are there any truly Mendelian traits where the trait displayed exists in a total binary? I have looked at some questions on the ...
gzkts's user avatar
  • 73
2 votes
1 answer
41 views

How to separate two plasmids from E coli with the same backbone?

I'm using transformation-associated recombination (TAR) in yeast to capture a biosynthetic gene cluster (32 kb) by transforming gDNA and a capture vector (11 kb) with homology arms. I identified a ...
Omar Antonio Ocegueda's user avatar

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