Questions tagged [genetics]
Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.
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Patterns of craniofacial topology
There are animals which are not directly related but have similar craniofacial topology.
For example: koala, donkey, mouse, turtle, parrot all have features seemingly belonging to same topology, ...
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Reading genotype aloud
For this genotype, P2ry12$^{+/+}$ I read it "P2ry12 wild type." For animals with the GFP being expressed under one Cx3cr1 promoter, Cx3cr1$^{+/GFP}$, how do I read that aloud?
What about for:...
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How to resolve the contradiction between the time required for the fixation of neutral mutations and the time available according to the fossil record
More than thirty thousand synonymous single-nucleotide-substitutions have occurred in protein-coding genes in the human genome since the human lineage diverged from the chimp lineage ~7 million years ...
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Why is the expected time to coalesce the same as the ploidy times inbreeding effective population size?
The expected time to coalesce, in generations, is the same as the ploidy (e.g., 2 for humans) times Nef, the inbreeding effective population size, under coalescent
theory. Why?
Both ploidy * Nef and ...
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Have there ever been "half-twins" who were halfway between siblings and twins?
Have there ever been two human siblings who were 75% or more genetically related?
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Has perturbation theory been applied to mutation process frameworks?
For example, imagine this Feynman diagram:
This is analogous to mutational homoplasy.
When comparing haplotypes, there are many possible tree topologies. Under maximum parsimony, we ignore suboptimal ...
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How exactly are the eye color genes related?
How exactly are the gey (maybe aka EYCL1?), bey(2?) (aka EYCL3?), HERC2, and OCA2 genes related to each other? There are numerous sources that explain eye color in terms of OCA2's role in the creation ...
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What are the chances that two children of the same couple will have the same genes without being identical twins?
If I randomly select half the chromosomes of the male and female eventually I will select the same exact half for both a second time. How often does this occur? Is this considered a twin if it is born ...
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How did the Zinder-Lederberg experiment on Transduction work?
In the paper that introduced TRANSDUCTION (J Bacteriol. 1952 Nov;64(5):679-699), Lederberg and his student Zinder reported that S. typhimurium
"LT-22 is lysogenic for a virus active on LT-2. ...
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Bacteria genetic screen for mutants
Is there a simple screen for bacterial mutants with increased mutation rates? For example, detection of some loss-of-function mutation that causes increased mutation rates.
Any screen I can think of (...
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Change of DNA concentration due to restriction digest?
Assume that you perform a restriction digest in a molecular biology lab: you combine genomic DNA, a restriction endonuclease (e.g., EcoRI), and the optimal buffer for that endonuclease and are about ...
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Coefficient of fraternity between grandparent and grandchild from full-sib parents
I have the following pedigree and I would like to calculate the coefficient of fraternity between individual 1 and 5. R/AGHmatrix::Amatrix gives a coefficient of 0 for this pair. Shouldn't it be non-...
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Gene Mapping - Please explain in Lay terms
Taking an AP bio course, and for some reason I cannot comprehend the mechanism of how one determines the location of alleles on a chromosome. The math is simple and I can memorize it, but its bugging ...
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What software can be used for simulating human meiosis, taking linkage and recombination into account?
I want to study the nature of genetic variation in offspring from the same set of human parents. To this end, I would like to take two (male and female) complete genomes, generate gametes from them, ...
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Is there any objective way to describe ethnicity?
Is there any objective way to describe ethnicity that does not rely on arbitrary sociocultural concepts like referring to racial constructs, modern nations like “Spanish”, or even continents like “...
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