Questions tagged [genetics]
Genetics is the branch of biology that deals with the transmission and variation of inherited characteristics.
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Is there a convention regarding the use of forward vs reverse DNA strand to represent DNA sequence?
I see in this paper the notation IL-1A C[-889]T which suggests that for this gene, the reference allele is C and the variant is T.
However, when I look up the same gene on dbSNP, it says the alleles ...
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How to calculate df in the chi-square test of Hardy-Weinberg equilibrium? [closed]
We often use df=1 in Hardy-Weinberg equilibrium when there are only two alleles. Some people say that it's because we've used the frequency of two alleles when calculating the expectated values, while ...
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Why is the maximum propotion of MII 2/3 in the ordered tetrad analysis? How is it different from normal recombination?
My textbook says that the maximum propotion of MII gametes in the ordered tetrad analysis is 2/3, and if we put it into the formula RF(recombination frequency)=MII/2(MI+MII), we can find out that the ...
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Are Hardy-Weinberg equilibrium assessment for two alleles on one loci or two locus?
Are Hardy-Weinberg equilibrium assessment for two alleles on one loci or two locus? For instance, when the video says BB Bb bb https://www.khanacademy.org/science/ap-biology/natural-selection/hardy-...
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Is there potential to modify GM crops to inhibit their reproduction with non-GM crops?
I've been reading on terminator gene sequences and was wondering whether the same technology could be applied to GM crops to prevent transgene flow. Turns out Monsanto had developed the technology but ...
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Is the amount of pigment in one feature (e.g. hair, eyes, skin) connected to the amount of pigment in another?
Let's say, genes allowing it, you have a red-haired child with hazel eyes. The hair is a darker/deeper orange color, so (if I recall correctly) having some degree of eumelanin—not much compared to ...
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Hardy-Weinberg Equilibrium Test Result for Merged Genotypes
I was curious if two populations are in Hardy-Weinberg Equilibrium (HWE), and if they are merged, then what happens? To find out, I considered populations from the 1000 genome project data. For ...
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How frequently does recombination occur, and how long are the recombinated fragments?
I understand the mechanics of recombination, but am struggling with the 'scale'.
When two homologous chromosomes pair, roughly how many recombination events occur on average? I understand there will ...
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Can a person have different sex at cellular level?
I mean like every cell has a sex chromosome.So does a male with XY chromosomes has all the cells in all the organs inside his body of XY chromosomes only? And vice versa.....
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Do multiple alleles undergo crossover?
For a reference, point 3 of this article: https://www.biologydiscussion.com/genetics/multiple-alleles/multiple-alleles-meaning-characteristics-and-examples-genes/35452
According to google Bard and ...
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How many base codes are in DNA? Two or four?
We know there are four bases found in a DNA: adenine (A), cytosine (C), guanine (G), and thymine (T). We also know that A always pairs with T and G always pairs with C. Can we say that the DNA is ...
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What is the most accurate polygenic score for Alzheimer’s disease?
To date, which polygenic score (i.e. which study) has produced the largest effect size for Alzheimer’s prediction in out-of-sample validation?
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Are there two different senses of the word 'heritability' in use?
Target Height as Predicted by Parental Heights in a Population-Based Study states:
The heritability value was taken as the regression coefficient between
final height and midparental height
Is this ...
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Why do many plasmids for Flp-mediated Flip-Excision only flanked by one FRT site on each side and not two non-homologous?
I'm trying to build some molecular gene switches into a model, and want to use both Cre and Flp. I understand how to invert gene segments with Cre, double floxing (e.g. with loxP and lox2272, like in ...
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Could the inability of adult mammals to digest lactose be partially explained by the loss of lactose-metabolizing bacteria from the microbiome?
BACKGROUND:
1. Lactase persistence
Lactase persistence is the continued activity of the lactase enzyme in adulthood, allowing the digestion of lactose in milk.
According to Wikipedia, only a small ...
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