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Questions tagged [synthesis]

Synthesis is a purposeful execution of chemical reactions to obtain the desired product. Applies to long and complex natural product syntheses as much as to short one or two-step syntheses. This also covers synthetic problem sets and retrosynthetic analyses.

46 votes
3 answers
5k views

Do molecules with bridges through rings exist?

Do molecules with bridges through rings (in a manner illustrated by this) exist? I sometimes get results like this when doing Energy Minimization on molview.org. For example: Is this actually a ...
schuelermine's user avatar
28 votes
2 answers
3k views

Why are there no cheap diamond equivalents?

We recently learned in school that diamonds sparkle as the are very optically dense, meaning that it takes longer for light to pass through them, thus meaning that the light totally internally ...
Deep's user avatar
  • 511
24 votes
1 answer
1k views

Interlocked cyclic compounds

Being new to chemistry, there may ought to be some properties I couldn't understand fully. One of them being cyclic compounds. One particular question about this is, whether these cyclic compounds, ...
čaritisio's user avatar
23 votes
3 answers
585 views

Energy-efficiency aside, what are the chemical constraints on CO₂ capture and methanation?

Synthesising $\ce {CH4}$ from air and water (in a non-biological process) has been proposed as one form of energy storage. What are the chemical constraints at play here? That is to say, what sort of ...
410 gone's user avatar
  • 1,530
22 votes
2 answers
30k views

Clemmensen reduction vs. Wolff-Kishner reduction

In which cases is the Clemmensen reduction is preferred over the Wolff-Kishner reduction? One thing is that the Clemmensen reduction is done under acidic conditions whereas the Wolff-Kishner ...
user avatar
21 votes
2 answers
5k views

What is the mechanism of the reaction between hexane-2,5-dione and nitrous acid?

I don't understand the mechanism of the first reaction; I tried different ways but I can usually find how to make the ring without the double bonds, but it's obviously not the right thing; I think ...
Jake Q's user avatar
  • 213
20 votes
1 answer
2k views

ICHO Synthesis Problem 2018

I've several doubts about this ICHO synthesis problem, which was a part of the preparatory problem package of 2018 (so yes, it's not a part of an ongoing contest) Before sharing the answer given, I'...
stoic-santiago's user avatar
19 votes
2 answers
5k views

Designing a theoretical synthesis of methamphetamine from phenylpropyne

I am asked to synthesize "methamphetamine." Note that there is no configuration designated for this molecule, and methamphetamine refers to a very specific configuration. In any case, here are the ...
Dissenter's user avatar
  • 19k
19 votes
1 answer
2k views

Propose a chemical formula for the white solid that forms during the initial stages of the reaction of Sn with benzyl chloride

In my inorganic class, we carried out the synthesis of chlorotribenzyltin, $\ce{SnCl(CH2C6H5)3}$. The synthesis begins with a reflux I'll describe below: In a hood, place 2.0 g (17 mmol) of 325 mesh ...
John Snow's user avatar
  • 4,535
17 votes
2 answers
904 views

Which platonic solids have been built as carbon skeletons?

There are 5 platonic solids: the tetrahedron, the octahedron, the cube, the dodecahedron and the icosahedron. How many of these have been realised as carbon skeletons by chemical synthesis?
matt_black's user avatar
17 votes
1 answer
835 views

Understanding the synthesis of twistane [closed]

What are the products P and Q? This was a question in my test series, but I don't have any experience with bridge head compound regarding the cis and trans transformation. I need help understanding ...
Greninja's user avatar
  • 197
17 votes
2 answers
50k views

Reactions of alcohol with sulfuric acid

I knew two chemical reactions of alcohol with sulfuric acid $\ce{CH3CH2OH + H2SO4 -> CH2CH2}$ Here product is having a double bond (ethene) and this reaction happens at 443 K temperature. $\ce{...
manshu's user avatar
  • 734
17 votes
1 answer
997 views

Are there any significant uses of the compound formed by magnesium and anthracene?

In an unusual reaction, magnesium reacts with anthracene in THF to form a grignard-like compound called, prosaically, magnesium anthracene: I remember using it briefly in the 1980s. At the time there ...
matt_black's user avatar
17 votes
1 answer
599 views

Is it possible that diamond can be grown from aqueous solutions?

Assume a cubic diamond crystal with hydrogen-terminated surface bonds. The terminating hydrogen atoms will form pairs that are geometrically close together in alternating diagonal pairs (think of the ...
Terry Bollinger's user avatar
16 votes
4 answers
5k views

Why are solid phase organics often conjugated to HCl?

Many uncharged organic compounds are sold in solid phase with HCl conjugate - e.g. the antihistamine diphenhydramine.HCl or the derivitizing agent pentafluorobenzyl hydroxylamine.HCl, among many ...
Drew Steen's user avatar

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