Questions tagged [synthesis]
Synthesis is a purposeful execution of chemical reactions to obtain the desired product. Applies to long and complex natural product syntheses as much as to short one or two-step syntheses. This also covers synthetic problem sets and retrosynthetic analyses.
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Oxidative chlorination mechanism (sulfide to sulfonyl chloride)
I cannot find much guidance in the literature. Any ideas as to what the mechanism of this reaction might be?
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Synthesis of mandelic acid from benzaldehyde
For an upcoming exam, I have to describe the synthesis of 2-hydroxy-2-phenylacetic acid (mandelic acid) from benzaldehyde. The provided answers describe quite a long process, consisting of 8 stages. ...
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Synthesis of chloroquine from 4-amino-7-chloroquinoline
Can we get chloroquine from 4-amino-7-chloroquinoline (7-chloroquinolin-4-amine) by adding 4-chloro-N,N-diethylpentan-1-amine $(\ce{CH3CHCl(CH2)3N(Et)2})$ ?
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How to characterize gaseous ethylene that forms as byproduct?
I'm running a reaction that has ethylene gas as a byproduct. I have observed gas evolution as my reaction proceeded and I have other ways of verifying the identity of the main product, but I thought ...
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Is it possible that diamond can be grown from aqueous solutions?
Assume a cubic diamond crystal with hydrogen-terminated surface bonds. The terminating hydrogen atoms will form pairs that are geometrically close together in alternating diagonal pairs (think of the ...
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How can we synthesize para-nitrophenol
During nitration of phenol, both para- and ortho-nitrophenols will be formed.
Is there any way in which we can synthesize para-nitrophenol only?
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What is the geometric configuration of the four fluorine atoms during the synthesis of xenon tetrafluoride?
Neil Bartlett (1932–2008) first synthesized $\ce{XeF4}$ (and $\ce{XeF6}$) in 1962. In the synthesis, a nickel chamber is used, and heated to 400°C, causing the formation of $\ce{NiF4}$, which ...
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Acid catalysed synthesis of ethyl ethoxymethylenemalonate
One synthesis of quinolones begins with the formation of an ethyl ethoxymethylenemalonate, as seen in this Organic Syntheses paper.
I've been asked if the malonate derivative would be formed if ...
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Can recent developments improve the total synthesis of B-12?
The total synthesis of vitamin B-12 by Robert Burns Woodward and Albert Eschenmoser, is over 30 years old. At its time, it was considered a landmark in the field.
With current developments (e.g. ...
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