Questions tagged [biostatistics]
The science of statistics applied to the analysis of biological or medical data.
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Perfusion Analysis Counts as Survival Analysis?
In perfusion analysis, the patient is injected with some dose of medicine. A machine detects, over time, the dose of medicine in the patient's body. In other words, the data for each patient is time ...
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Survival analysis: usage of local control and local recurrence free survival [closed]
I noticed that in some publications the terms "local control" and "local recurrence free survival" are used interchangeably, in others the local control does not include the death ...
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Conducting a network meta-analysis in R - inputting dichotomous data
I am looking to conduct a meta-analysis in R using {netmeta}. However, my outcome of interest is a little bit complex and would appreciate advice in how best to enter it into the dataset.
I am looking ...
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calculating percentage normalisation
Please don't laugh or close this post I am confused as to how I can calculate the percentage normalization occurring post treatment.
So, here is a background of the problem, I have reading from ...
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How to know what sample size (number of cells) is sufficient to determine what percentage of cells are above a threshold?
I have a samples with different cell types (one cell type is shown above). I have calculated for each sample and cell type a threshold signifying non proliferating vs proliferating cells. Cells above ...
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Correlation alternatives / How to go about testing this relationship?
I have a large set of temperature data from upstream and downstream gauges. I am trying to find the influence of dam release on downstream temperatures. To do this, I am comparing correlation between ...
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post-hoc test for multinomial logistic regression brm model (categorical response)
I apologise as I am very new to this package and I really appreciate any help I can get.
I have a brms model with a categorical response variable (Species) with the ...
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How to interpret my GLM results [closed]
I'm running a GLM to see if there are any differences in % cover of fescue and native grasses along a bison use intensity gradient (Do we have more fescue or more native grasses where there are more ...
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Validating Model Setup for Differential Abundance Analysis Using ANCOM-BC in R
I am conducting an analysis on microbiota data from a study involving 55 women, categorized by pregnancy status and BMI (lean vs. obese). The goal is to explore the differential abundance of ...
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Long term monitoring data statistics help [closed]
I am still learning statistics and I have some long term monitoring data taken from soil samples in two different forests over 5 months. Soil chemical parameters such as pH and redox, carbon and ...
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Modelling longitudinal pre-/post-intervention data
I have longitudinal data of a number of patients for which some biomarker was measured at irregular time intervals over the course of several years before treatment and over a shorter period of time (...
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log ratio transformation on data and GLM testing on 4-way olfactometry results
I recently completed an experiment looking at 40 individual aphids movement over 20 minutes inside a 4-arm olfactometer with 3 controls (no scent, uninfected aphids, agar) and aphids infected with the ...
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How to perform a power analysis for poisson distributed data
I want to perform a simplified power analysis to determine how many cells (samples) to have in control and experimental conditions (assume equal n across conditions). For an alpha level of 0.05, 0.95 ...
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How to deal with replicates and z-scores?
How would you deal with replicates if you want to calculate z-scores?
My ultimate goal is to make a heat map of gene expression. To do so I have to calculate z-scores.
The analysis consisted of some ...
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Rank correlations: what is the difference between spearman coefficient and $R^2$? [closed]
When the data are not normal, how can the Spearman rank coefficient be interpreted differently from $R^2$?
As I understand it, when performing a rank correlation, the axes typically shouldn't show the ...
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