Questions tagged [meta-analysis]
Methods focused on contrasting and combining results from different studies, in the hope of increasing precision and external validity.
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Rescale measures of association for meta-analysis (e.g., log-transformed independent variables)
I am carrying out a meta-analysis of studies evaluating the association between blood levels of specific environmental pollutants and health outcomes (binary).
Some studies reported OR/RR/HR for ...
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How to handle dependent effect sizes in meta-analysis with a single control group?
I am conducting a meta-analysis and need advice on extracting effect sizes from studies where multiple treatment groups are compared to a single control group. Specifically, I am dealing with standard ...
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Related low p-values that do not meet statistically significant thresholds
If I were to have multiple related measures, each with "low" p-values that do not quite meet the threshold of significance, could the fact that multiple measures produce a general trend with ...
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Conducting a network meta-analysis in R - inputting dichotomous data
I am looking to conduct a meta-analysis in R using {netmeta}. However, my outcome of interest is a little bit complex and would appreciate advice in how best to enter it into the dataset.
I am looking ...
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How to find difference between two hazard ratios (ratio of hazard ratios)
I am reading a meta-analysis and in this paper the authors somehow compared HR from two groups with different treatments in each study. As I know, we can compare outcomes from two groups with ...
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Analyzing an experiment which consists of many "small" experiments
Consider the following setting: I am trying to choose between two bakers for my new bakery, Baker A and Baker B. The way that I am evaluating them is on a set of different cakes on the menu: Cake 1, ...
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Robust Variance Estimation or Cluster Wild Bootstrapping on a multivariate meta-analysis
Cliffnotes
Can I use RVE or cluster wild bootstrapping in meta-analytic models that are not
meta-regression?
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I am conducting a three-level meta-analysis looking at the effects of a particular ...
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Conditional Logit Model - Utility Structural Estimation - Meta Analysis
I am performing a structural estimation of an utility function across several databases (from distinct articles) using McFadden (2001) framework (see reference).
Each article's database includes N ...
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Understanding correlated and hierarchical effects models in meta-analysis
I am doing a three-level meta-analysis, and I want to compare a three-level correlated and hierarchical effects model where effects are nested between-studies to a two-level model where variance at ...
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I was trying to calculate standard error from log odd ratio, Is this calculation correct?
I have two datasets. The first dataset have odd ratio, 95% confidence interval, p-value, and 2x2 table. while, the second dataset only have odd ratio, 95% confidence interval, and p-value without 2x2 ...
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Pooled Hazard Ratio or Crude events (M-H to RR or OR) for mortality outcomes in Meta-Analysis?
I'm performing a MA to estimate the effect of treatment A respect to Placebo (or propensity-matched control group) respect to all-cause death.
All the studies included in my MA report both crude ...
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Can I do a meta-analysis of categorical outcomes by assigning them to ordinal values in single-arm studies?
I have a collection of case reports and single arm cohort studies (without control groups) that describe the clinical response of patients treated with a particular drug. The response is reported ...
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Outlier and influential analysis for multilevel meta-analysis with robust variance estimation
I am conducting a three-level meta-analysis where I have different dependency structures in my data. I model the dependency by approximating the var-cov matrix, followed by estimating a three-level ...
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Is it possible to calculate effect size from the relative pre-post change?
I am trying to conduct a meta-analysis that focuses on the pre-post change of an intervention. While most studies reported the pre and post mean and SD scores of the outcome, some only reported the ...
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Why are 1/SE or 1/variance commonly used as weights in regressions?
I'm trying to do a meta-analysis for the first time, comparing measurements of a simple experiment treatment against a control in a variety of species. I started by fitting a mixed-effects model to ...
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