Questions tagged [epidemiology]
Epidemiology is the study of the distribution and spread of disease or illness at the population level.
477
questions
0
votes
2
answers
27
views
Relationship between sensitiviy, probability of detection and Prevalence
Folks, I have 3 questions:
If I know the number of exams performed with a specific test on a group of patients and the test's sensitivity, can I directly estimate the overall probability of detecting ...
1
vote
0
answers
20
views
Sample Size: Cluster Randomized Trials
I seek a peer check on my approach in calculating the sample size for pair-matched or stratified cluster randomized trials assuming 80% power.
Some background on the study: I am working with ...
- 103
-1
votes
0
answers
14
views
Survival analysis: usage of local control and local recurrence free survival [closed]
I noticed that in some publications the terms "local control" and "local recurrence free survival" are used interchangeably, in others the local control does not include the death ...
- 1
0
votes
0
answers
27
views
Calculating death rates for an increasing population over the long-term
I'm part of a small long-term outcomes study for a specific MH intervention. We're becoming a little alarmed at the number of subjects who seem to have died in their 20s and we'd like to make sure ...
1
vote
0
answers
14
views
What standard population to use in my epidemiological study?
I need to standardized my mortality rations. for the period 2000-2022 in one European country. However, I am not use what standard population to use? Is Sagi outdated? In addition, I find this ...
- 11
1
vote
0
answers
14
views
penalized package [closed]
Has anyone used penalized package? I was using it for lasso in Cox regression, with time-varying coefficients.
The problem is when I made a plot with ...
- 11
1
vote
0
answers
15
views
Is this non-mathematical interpretation of cause-specific vs subdistribution hazards sensible?
I am interested in estimating the risk of readmissions accounting for the competing risk of death. I would like to explain both types of models to people with a basic understanding of statistics.
...
- 11
0
votes
0
answers
27
views
Sample size for a vector of proportions and simulation
Currently, there are more than 10 variants of omicron virus.
Say, variant proportions are X1=0.1, X2=0.35, X3=0.15, etc. I need to calculate the number of samples needed to detect the proportion of ...
0
votes
0
answers
11
views
How to deal with exposure status change and outcome contribution in different exposure status?
I want to estimate the risk of cardiovascular events in patients with diabetes (exposed group) compared to patients without diabetes (unexposed group). How do we deal (in the analysis) with patients ...
- 101
0
votes
0
answers
10
views
Variability of patients in different Hospitals
just to let you know that my statistical background is not very good. I made funnel graphs which shows the effect of polypharmacy against practice size.
In the funnel graphs, a dot presents a single ...
- 141
1
vote
1
answer
79
views
Incidence rates from manual calculation differs from that obtained from the estimated marginal means of a poisson regression
Poisson Regression
I have done a poisson regression where the data is individual-level data, the dependent variable, event is 1 if individual had the event or 0 if ...
- 227
0
votes
0
answers
15
views
How to perform conditional poisson regression for a 1:5 matched cohort study?
I have a matched cohort population using data that spans the years 2016-2021. My exposure of interest is continuous dialysis treatment, and my outcome is e.coli infections (count outcome). Each time ...
- 1
0
votes
0
answers
23
views
Proportion mediated possible for Binary outcome, Continuous mediator?
I am running a mediation analysis on a categorical X (race/ethnicity), binary Y (disease status), and ordinal M (can be any integer 0 - 10). N-controls = 1321. Ncases = 384. I conducted this analysis ...
- 21
3
votes
3
answers
90
views
Interpreting Poisson GAM for epidemiological model
I'm working on a project where I investigate the relationship between PM2.5 (a form of pollution) and ischemic stroke hospitalization (i.e. number of hospitalizations total, collected per day). My ...
- 151
1
vote
0
answers
100
views
Region of Practical Equivalence (ROPE)
I seek to understand how to employ the Region of Practical Equivalence (ROPE), so I conducted a basic Bayesian analysis of disease incidence rates on a public data set.
Is my rationale sound regarding ...
- 103