The document discusses a roundtable report on the implications of the Topol Review for the pharmaceutical industry. The Topol Review explored how to support digital healthcare technologies in the NHS. The roundtable addressed questions about ensuring personal care in a digital environment, bridging digital divides, and benefits of technologies like genomics and AI. Key points discussed included the need for patients to be partners, addressing skills and access issues, and the industry needing to adapt to remain relevant in a changing healthcare system focused on personalized care.
A review of the health sensor market estimated at 400M devices and worth $4B by 2014, including 36 companies offering devices across the wellness, chronic, diagnostic and monitoring markets. Purchase the report here: https://gumroad.com/l/Khrd
Co-Creation with Customers-By Aviroop Banik,Rizvi Institute of Management Stu...Aviroop Banik
This document discusses co-creation of value with customers. It begins by noting that consumers now have more choices but less satisfaction due to being more connected, informed and active. This shifts the role of the customer from passive to active. The document then provides examples of how customers now have more information access, a global view, greater networking abilities, and opportunities for experimentation and activism. It argues that value is now co-created between firms and customers through dialogue, access, risk assessment, and transparency. It provides the example of a houseboat manufacturer that engages in intensive co-creation with customers through design discussions, manufacturing access, and community involvement.
Key lessons learned from the worldwide pandemic
Keynote presentation at the Digital Transformation of Pharmaceutical Industry conference organised by United Journal and Conferences on April 13th 2021
Final file of digitive healthcare ilovepdf-compressedinsightscare
Such healthcare providers always foster a healthy team environment at their workplace and engage in behaviors that benefit the team and display empathic behaviors when interacting with patients and their family members. To highlight such great healthcare providers, we have come up with an issue of “The 10 Most Innovative Digital Healthcare Solution Providers 2018”.
Pharma Marketing Digital Trends to Watch in 2020. A closer look at some of the future directions that Pharma Marketing need in 2020 to arm themselves for in full readiness for the next 12 Months
Virtual care is on the rise as consumers increasingly demand convenient, affordable, high-quality healthcare options. Retail clinics were an early example of meeting these demands through convenient locations and hours. Now, virtual care via mobile apps, websites and video visits further improves convenience by allowing care from anywhere. Studies show consumers strongly value these convenient options and are willing to switch providers to get them. As technology empowers patients and competition grows, healthcare providers must adapt to these new expectations around accessibility, service and customer experience or risk losing patients to competitors that do.
This presentation offers an overview of the Digital Health space, including thematic investment areas, business models, metrics for evaluation, and adoption models for digital health interventions.
Health Innovation Frontiers - Untapped Market Opportunities for the 50+Sanjay Khurana
By 2018, the 50+ population is forecasted to spend almost $100 billion, out of pocket, on healthy living solutions. Rarely has such an untapped opportunity existed to generate revenues for entrepreneurs, investors and others in the private sector to generate revenues while meeting the greatest wants and needs of a substantial, influential and important population: people 50 and over. This report looks at investment potential and market dynamics across Nine Identified Areas of Health Innovation for the 50+.
The future of healthcare: when mobile disappearsMatteo Penzo
In today’s digital world, mobile devices are the powerful bridges between a connected ecosystem of healthcare professionals, caregivers and patients. New developments in big data, wearable sensors and the application of social layers are shifting an industry that used to focus on curing diseases to one that emphasizes health and wellness. But the mass adoption of connected healthcare will only happen when solutions are designed to be intuitive and technologies are forgotten. The future of healthcare will happen when mobile disappears into the background, placing the patient in the center and in control of their lives.
Health Care is facing massive transformation. There is a lot to be learned from the Internet Industry and open standards like OpenID, OAuth and Microformats.
By 2020, the number of Americans who are expected to need assistance is projected to be 117 million, yet the number of unpaid family caregivers is expected to reach only 45 million. We need technology more than ever to bridge the gap. Project Catalyst, in collaboration with HITLAB, conducted a survey with over 1,000 caregivers, aimed at identifying their technology interest and usage. The research found that caregivers have a high interest in using technology to care for their loved ones – 71 percent of survey participants expressed interest in using technology to support caregiving activities while less than 10 percent have currently or previously used caregiving technology. Adoption rates are low due to a range of factors including lack of awareness, high cost, perception that technology may not be a benefit, and lack of time to learn and adapt new technologies. This presents an opportunity for the technology industry to leapfrog existing offerings and provide viable alternatives to the 40 million caregivers actively seeking ways to lessen their workload.
Capgemini Consulting: Taking the Digital Pulse: Why Healthcare Providers Need...VIRGOkonsult
Healthcare providers are lagging in their adoption of digital technologies compared to other industries. While consumers are increasingly using digital tools and online resources to manage their health, most healthcare providers have not adapted to meet these changing needs and expectations. Only about one-third of healthcare providers are considered digitally mature, while the majority are still in the early stages of digital transformation. Digitally mature providers leverage social media, mobile apps, and data analytics to better engage with customers, personalize care, and improve health outcomes. However, most providers lack a clear digital strategy and vision, underinvest in necessary technologies, and do not utilize data and digital channels effectively. This limits their ability to keep pace with consumer demands and transform service delivery in a
Better Together 2019 Patient Services Survey - Condition Resultsaccenture
Accenture Life Sciences online survey of 4,000 patients across four countries and three conditions reveals how patients use and value services from patient organizations. Explore the unique differences by condition. Visit https://accntu.re/2Y9CGqw to learn more.
Healthcare delivery is becoming an increasingly complex operation. Nurses, physicians and other allied healthcare professionals are increasingly measured on their quality of work, even with increasing patient volume and patient complexity. Technology, from sensors to analytics to software based decision support and automation, have the potential to both leverage our healthcare provider workforce to mange increasing demands and to improve quality. This presentation will focus on the key areas of opportunity for technology to improve the capabilities of healthcare providers in delivering quality care.
COVID-19 has significantly impacted mental health and increased focus on treatment and support. Telehealth has grown due to reduced access to healthcare services and stress on health systems. Employers also face challenges supporting staff mental health due to changes in work environments and protocols. Looking forward, 2021 will see continued prioritization of mental health and evaluating impacts through the lens of the ongoing pandemic.
Medtech Joining the Digital Party - December 2015Megan Aparicio
The document discusses how the medical technology (medtech) industry has been slower than other industries and sectors of healthcare to embrace digital transformation. A survey found that only 33% of medtech companies see digital technologies as a major disruptor compared to 57% across all industries. Medtech companies also lag in having a clear digital strategy, properly structured organizations for digital initiatives, and appointing dedicated digital leadership roles. For successful digital transformation, the document recommends medtech companies focus on strategic clarity, appropriate structures, defining ownership of digital efforts, and hiring the right digital talent.
The document summarizes a panel discussion on digital health held by the INSEAD Healthcare Club of Switzerland. It discusses how digital health has the potential to transform life sciences through technologies like sensors, data collection, and precision medicine. However, significant regulatory hurdles around data sharing and privacy still exist. While companies like Bristol-Myers Squibb and Novartis are pursuing digital health projects, it is unclear which players like pharmaceutical companies, technology giants, insurers, or patients will ultimately lead the transformation. The panelists debated these issues and shared lessons learned from their experiences in digital health.
DOWNLOAD DECK: https://bundl.buzz/industryfuture
Discover the effects of Covid-19 and what the future normal looks like for consumers and the industries that serve them.
- Understand how uncontrollable forces set the scene in transforming consumer behavior in each industry.
- Find out how consumers and companies responded– its long-term and digital effects.
- See real innovation examples that reveal what the future of these industries and our world looks like.
DOWNLOAD DECK: https://bundl.buzz/industryfuture
Technology has the power to improve access to healthcare services, especially for people with mobility problems. Mobile technology can empower patients and carers by giving them more control over their health and making them less dependent on HCPs for health information.
Find out how Digital Healthcare works out for the best for both the consumers and the providers of healthcare alike. We at EMed HealthTech are doing its bit in helping accelerate this development through its enterprise health app and software applications, telemedicine software, healthcare ERP and other custom solutions that help healthcare providers connect with patients.
Connected health, also known as technology-enabled care (TEC), involves the convergence of health technology, digital media, and mobile devices. It enables patients, carers, and healthcare professionals (HCPs) to access data and information more easily and improve the quality and outcomes of both health and social care.
Healthcare Rx: The Rise of the Empowered ConsumerCognizant
Market and digital forces have combined to enable the healthcare industry to treat much of what ails it — or be supplanted by newcomers who can more quickly seize the digital high ground.
The document discusses upcoming transformations in healthcare delivery models by 2025. It notes that current systems are straining to meet demands due to aging populations and rising chronic diseases. Healthcare will shift towards preventative, patient-centric models using digital technologies to enable anytime, anywhere access. This will involve moving care locations closer to patients' homes and empowering individuals to take ownership of their health through tools that monitor health and wellness. By 2025, digital health solutions will be more commonplace as reimbursement policies change and technology-savvy generations increase adoption of tools like wearables, telehealth, and mobile health.
Here's a quick recap of all that inspired us HLTH this year. Creating the future of health as heard from business leaders far and wide. This particular conference gives us a moment to take a pause, immerse in the total health ecosystem and to challenge our thinking about our role in creating what's next. Congrats to Jonathan Weiner for an incredibly successful year 2 of this amazing convention.
Big data has the potential to significantly impact healthcare and medicine by enabling the discovery of patterns within vast amounts of data. For the first time, adequate computing power and machine learning algorithms exist to analyze both structured and unstructured data at scale. This could lead to innovations like predicting disease outbreaks from search engine or social media data, and more personalized medical treatment based on a patient's individual risk factors and data patterns over time. However, big data in healthcare remains roughly defined and raises concerns around data privacy and security that must be addressed. If these challenges can be overcome, big data may help fuel major advances in areas like predictive medicine, medical decision support, and a shift towards more proactive and customized care models focused on the patient.
The 10 companies booming in healthcare sector smallinsightscare
Development is a continuous process in any sector. It brings in more comfort, more precision, and more enhanced way of living.Acknowledging the remarkable contribution of the leading companies in the care sector, we bring to you the special issue of “The 10 Companies Booming in Healthcare Sector”.
This document provides an investment thesis for consumer-driven healthcare startups. The thesis is based on several trends including the aging population, rising healthcare costs, increased consumer demand for flexible healthcare options, and the expansion of social media and technology. The document argues that investments in startups focused on consumer healthcare through technological solutions that leverage data analytics and ensure alignment with consumer lifestyles and affordability will be most likely to succeed. Several example startup opportunities are provided to illustrate the thesis.
This document summarizes discussions from a series of events on technology ventures. It addresses 21st century paradigms for innovation, new innovation models, and focuses on digital technologies, biotechnology, and healthcare. Key topics discussed include using data and incentives to encourage preventative healthcare, balancing public and private use of health data, and how new firms are driving innovation in genomics and new drug discovery models through collaboration.
Disruption Set in Motion by Healthcare Consumerism.pdfMindfire LLC
Healthcare consumerism is the health industry’s shift towards a more value based care; it is a movement for a more cost effective and efficient delivery of healthcare services. It connotes the patient taking control of their health and wellness by managing all aspects of one’s healthcare landscape – including health benefits, medical insurance and retail health. In short, the goal of healthcare consumerism is to enable patients to become wholly involved in their healthcare decisions.
1) Developed countries aim to increase patient accountability and focus on education and awareness programs to promote healthier lifestyles.
2) Developing countries struggle to meet basic healthcare demands of large populations due to limited funding and infrastructure.
3) Examples provided of successful programs in Finland and the US that use incentives and competitions to encourage physical activity and reduce chronic diseases.
New Revolution in Healthcare — Digital Health.pdfinsightscare
Digital health technologies are transforming healthcare by detecting and treating illnesses early through tools like wearable devices, telehealth, and personalized medicine. This transformation allows for more efficient, tailored, and affordable healthcare delivery. While digital health improves access and healthcare outcomes, challenges remain around data sharing and privacy, as well as ensuring equal digital access. Emerging trends in digital health include telemedicine, wearable devices, robotic surgery, 3D bioprinting, and augmented reality, all of which are improved by technologies like cloud computing, big data analysis, and 5G networks.
The document discusses global trends in the digital healthcare industry and regulation. It notes that in 2018, a record $14.6 billion was invested globally in digital health, continuing a trend of annual increases since 2015. However, Korea does not have any of the 38 digital health unicorn startups valued over $1 billion that exist globally. It defines key terms like digital health, mHealth, and personal genomics. It also discusses regulatory issues and the increasing role of artificial intelligence. The future of digital medicine is that it will become integrated into ordinary medicine.
Creating a telemedicine app requires a combination of technical expertise, design skills and a deep understanding of the healthcare industry. The process starts with defining the app's purpose and identifying its target users. The next step is to create a detailed plan that outlines the app's features, functionalities and user interface. It's important to consider the security and privacy of patient data, as well as the regulations surrounding telemedicine. Once the plan is in place, a team of developers and designers can start building the app using the latest technologies and programming languages. Testing and quality assurance are crucial steps in the process, as they ensure the app is functional and user-friendly. Finally, the app needs to be deployed and marketed to reach its intended audience. With the right team and approach, creating a telemedicine app can greatly improve access to healthcare and help connect patients with healthcare providers in a convenient and efficient manner.
Similar to Is Technology Removing the ‘Care’ from Healthcare? (20)
MSL partnered with research firm Toluna to survey 1,846 marketing and communications leaders from Brazil, China, France, Germany, India, Italy, Poland, United Kingdom and the United States.
Powered by AI: Communications and Marketing in the Algorithm AgeMSL
MSL partnered with research firm Toluna to survey 1,846 marketing and communications leaders from Brazil, China, France, Germany, India, Italy, Poland, UK and US. We partnered with our colleagues at sister agency Publicis.Sapient who are experts in counselling companies and brands on the AI revolution.
A look inside the endless debate between traditional and digital media.
For more information write to Joshua Gardner, Vice President & North American Lead, Global Energy Practice, MSL | joshua.gardner@mslgroup.com
SCOTUS Launches New Economy with Legalized Sports BettingMSL
In a 6-3 decision in the case Murphy vs. National Collegiate Athletic Association, SCOTUS ruled that because Congress exceeded its constitutional authority when it passed PAPSA. In essence, Congress tried to prohibit state legislatures from repealing their existing statues that outlawed sports betting. Under a line of Supreme Court precedent known as the anti-commandeering doctrine, federal efforts to coerce states into enforcing federal law are unconstitutional violations of the Tenth Amendment.
To say this is just the beginning would be cliché, but what SCOTUS has wrought with its decision will have lasting consequences that go far beyond sports betting.
Our current consumption patterns are stretched to breaking point. Few would argue the need to fix our systems. It’s how to manage an economically viable and just transition that is making heads ache.
[Salterbaxter Directions] Moving The Goal PostsMSL
Is your business goal-ready to move beyond 2020? Explore a new generation of emerging sustainability goals that are unlocking business returns and driving transformational change.
The food market will experience rapid evolution in 2018, according to sector experts at MSL. A broad array of technological innovations will make it easier to acquire and consume foods and beverages tailored to our specific food needs, speeds and philosophies.
These insights emerge from the MSL’s annual analysis of top food trends compiled by its highly specialized food marketing and PR team, appearing as a shareable infographic. In recent years the agency’s forecast has been viewed more than 100,000 times. Past forecasts have spotted the emergence of major marketplace successes, including turmeric, coconut, ugly produce, food waste reduction and coffee as an ingredient.
The Second Technology Revolution: How the PR Business Needs To Change Once AgainMSL
The document discusses how the PR industry needs to change and adapt to a second technology revolution driven by emerging technologies like artificial intelligence, augmented and virtual reality, and big data analytics. It argues that these technologies are augmenting influence by providing more data-based insights, amplifying emotional resonance through immersive experiences, and using artificial intelligence to automate and adapt interactions. This will disrupt traditional media and influence, requiring PR practitioners to develop new skills in data, technology, and storytelling to help clients navigate this changing landscape.
SDG Signals - SBTribe Research by Salterbaxter MSLMSL
It’s been two years since the launch of the SDGs and the UN’s recent progress report highlights that support is uneven and needs to accelerate. New data sources, including
social media, continue to be vital tools to measure, monitor and report progress.
SDG Signals uncovers new insights about SDG communications online and which areas, people and brands are cutting through. We explore the overall SDG online conversation, providing clear opportunities for differentiation, with initial comparisons from the Technology and Food & Beverage sectors. Future editions will put the spotlight on other specific sectors and issue areas.
A joint initiative conducted by MSL and SPARK Neuro gives PR pros true cause for excitement. What was once only subjective – how much people are engaged with content and their emotional experience with it – can now be directly quantified by reading brain activity and other neurological responses.
For more information about Conversation2Commerce, email Erin.Lanuti@mslgroup.com or visit www.publicisC2C.com.
In PR2020, experts give us their perspective on what’s coming next in terms of tech disruptions, and how they believe this will impact the work we do. We explore influence, data, human science and machines, and our relation to them as communications professionals, business owners, governments, and human beings.
Write to us to start a conversation on how we can help you distill actionable insights and foresights from conversations and communities.
For more information contact Pascal Beucler, SVP & Chief Strategy Officer, Global, MSL (pascal.beucler@mslgroup.com) and Melanie Joe, Consultant – Research & Insights, MSL (melanie.joe@mslgroup.com)
[Salterbaxter Directions] Human Rights - The Time is NowMSL
Is your business up to speed on the risks and opportunities of human rights issues?
Learn from the early adopters of the UN Guiding Principles Reporting Framework and get ahead of the game.
For more information, connect with @salterbaxterMSL or reach out to us on Twitter @msl_group.
News in the Times of Digital - Indian Media TrendsMSL
The way India consumes news is changing in this digital age. 20:20 MSL's media trends infographic assesses Print v/s Online media consumption and how communications professionals can choose the right media mix through a structured approach.
Connect with our insights experts or share your feedback with us on Twitter @2020MSL and @msl_group.
To supplement Qorvis MSLGROUP's Guide to the Trump Administration, we have created a set of appendencies highlighting expected cabinet and staff appointments as of 12/1/2016.
Governing a Divided Nation - Insights about the 2016 U.S. Presidential ElectionMSL
Public affairs and policy experts from Qorvis MSLGROUP have compiled an extensive election coverage and analysis of how the new U.S. President and Congress will move forward after one of the most bitter campaigns in American history.
For more updates, follow @qorvis or reach out to us on Twitter @msl_group.
Each year, Directions takes an in-depth look at an area of sustainability and communications. This time, we’re delving into the quite sizeable gap that still exists between business and society. It’s not the void that interests us so much as the question of how it can be shrunk.
How do we move from just minding the gap to actually mending the gap?
For more information, connect with @salterbaxterMSL or reach out to us on Twitter @msl_group.
This document provides an overview of key people in Donald Trump's administration, including family members and advisors. It outlines biographies of Melania Trump, Ivanka Trump, Jared Kushner, Donald Trump Jr., Eric Trump, and Tiffany Trump. It also profiles powerful advisors and supporters such as Mike Pence, Reince Priebus, Steve Bannon, Newt Gingrich, Rudy Giuliani, Jeff Sessions, and Mike Huckabee. The document groups the individuals and provides affiliations for each to help understand the relationships that may influence the Trump administration.
The ICCO Global Summit which took place in Oxford, UK, from 29-30 September, 2016 offered two days of great conversations with colleagues coming from all over the world. MSLGROUP's SVP & Chief Strategy Officer, Pascal Beucler was invited to discuss why Branded Content and Entertainment are a new boundary, and a sweet spot to hit for PR professionals.
Based on Pascal's experience last June at the Cannes Lions International Festival of Creativity, as a juror in the newly created Entertainment Jury: this has been a week-long fantastic experience, evaluating how talent and ample narrative formats can elevate content into the cultural mainstream.
FIRST 1000 DAYS NI BABY PAHALAGAHAN PARA SA MALUSOG NA KINABUKASANangelicarrot0827
The first 1,000 days refers to a child's life from conception until they reach 2 years of age (24 months). This is a time when their brain, body and immune system grow and develop significantly. During pregnancy, your health, nutrition and stress levels can have an effect on your baby's future.
2024 07 12 Do you share my autistic traits_ - Google Sheets.pdfCarriePoppy
I made this spreadsheet when I was waiting for my autism assessment. It helped me determine that I probably have autism. When I did get tested, they (UCLA) told me I do, indeed, have Type 1 autism. You can use this spreadsheet to compare your experience to mine. I am a white woman, AFAB. My diagnosis is Type 1 autism with a pragmatic language deficit.
Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. They may also be called vermifuges or vermicides
Heart Valves and Heart Sounds -Congenital & valvular heart disease.pdfMedicoseAcademics
This presentation, authored by Dr. Faiza, Assistant Professor of Physiology at CIMS Multan, delivers an in-depth analysis of heart valves, heart sounds, valvular heart diseases, and congenital heart defects. It begins by distinguishing between normal and abnormal heart sounds, elucidating the timing and causes of the four heart sounds—S1, S2, S3, and S4—and their clinical significance. Detailed explanations are provided on the auscultation sounds that define conditions such as mitral stenosis, mitral insufficiency, aortic stenosis, and aortic insufficiency, with a focus on how these pathological changes affect cardiac mechanics and blood pressure.
The presentation delves into abnormal heart sounds, known as murmurs, categorizing them by their causes, which include valvular lesions, rheumatic fever, aging, congenital heart diseases, viral infections during pregnancy, and hereditary factors. It explores the various types of murmurs, their timing within the cardiac cycle, and their association with specific valvular heart diseases such as stenosis and regurgitation. The intricate relationship between systolic and diastolic murmurs and conditions like anemia and ventricular septal defects is also highlighted.
Further, the presentation covers the pathophysiology of congenital heart diseases, offering a comprehensive review of conditions such as Tetralogy of Fallot and Patent Ductus Arteriosus. It explains the mechanisms of these diseases, their impact on cardiac function, and the clinical manifestations observed in affected individuals. The physiological adjustments of the circulatory system during exercise in patients with valvular lesions are discussed, emphasizing the reduced cardiac reserve and the risk of acute pulmonary edema.
Special attention is given to the compensatory mechanisms of the heart in response to valvular diseases, including the development of concentric and eccentric hypertrophy, increased venous return, and the eventual progression to heart failure. The presentation also examines rheumatic valvular lesions, aging-related aortic stenosis, and the specific challenges posed by these conditions, such as reduced stroke volume and increased metabolic demand.
This thorough exploration of heart sounds, valvular diseases, and congenital defects is designed to enhance understanding and clinical acumen, making it a valuable resource for medical students, healthcare professionals, and educators in the field of cardiology and physiology.
All the information you need to know about Hypothyroidism - Introduction,
Etiology, clinical manifestations, complications, pathophysiology,
diagnosis, treatment, precautions.
Prakinsons disease and its affect on eye.Riya Bist
Enhance your knowledge about Parkinsons' disease and about basic concept that medical personnel should know regarding this topic.It is very important to know about systemic disease and its impact on the eye so, here you can learn quickly about Parkinson's disease and its ocular manifestation.Download the ppt for visualization of animation.Thank you.
PICTURE TEST IN OBSTETRICS AND GYNAECOLOGY-Aloy Okechukwu Ugwu.pptxAloy Okechukwu Ugwu
This picture test will help medical students preparing for their final exams.
It will also be useful for resident doctors preparing for part 1 exam of National Postgraduate medical college of Nigeria and West African college of surgeons in Obstetrics and Gynaecology
Staphysagria is often indicated for individuals who have a tendency to suppress emotions and suffer from the effects of suppressed anger, grief or indignation. They may exhibit a tendency to have a fragile or sensitive disposition. Staphysagria individuals often have a craving for solitude and a desire for sympathy.
These lecture slides, by Dr Sidra Arshad, offer a simplified description of the physiology of insulin and glucagon.
Learning objectives:
1. Describe the synthesis and release of insulin
2. Explain the mechanism of action of insulin
3. Discuss the metabolic functions of insulin
4. Elucidate the effects of insulin on adipose tissue, skeletal muscle, and liver
5. Enlist the factors which stimulate and inhibit the release of insulin
6. Explain the mechanism of action of glucagon
7. Discuss the metabolic functions of glucagon
8. Elucidate the role of insulin and glucagon in glucose homeostasis during the fasting and fed states
9. Discuss the role of other hormones in the glucose homeostasis
10. Differentiate between the types of diabetes mellitus
11. Explain the pathophysiology of the features of diabetes mellitus
12. Discuss the complications of diabetes mellitus
13. Explain the rationale of oral hypoglycemic drugs
14. Describe the features of hyperinsulinemia
Study Resources:
1. Chapter 79, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 24, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 39, Berne and Levy Physiology, 7th edition
4. Chapter 19, Human Physiology, From Cells to Systems by Lauralee Sherwood, 9th edition
5. Chapter 3, Endocrine and Reproductive Physiology, Bruce A. White and Susan P. Porterfield, 4th edition
6. Insulin and Insulin Resistance, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1204764/
7. Complications of diabetes mellitus,
https://pdb101.rcsb.org/global-health/diabetes-mellitus/monitoring/complications
Yoga talk & yoga slides by Flametree Yoga 11 July 2024.pdfStuart McGill
Yoga talk and yoga slides on the benefits of yoga and meditation, how it works, and how to get more very low cost yoga, or meditation, or both, in your life.
STRATEGIES FOR RATIONALISING/REDUCING CAESAREAN SECTION RATE BY USE OF "SION ...Niranjan Chavan
The journey to reduce/rationalise the C-section rate started in June 2023 and it’s an ongoing study been carried out at #SionHospital #LTMMC Mumbai.
It’s going to revolutionise the journey of motherhood for safer, predictable maternal and fetal outcome.
The SION model is a structured and networked approach to promoting vaginal deliveries.
By integrating education, support, policy implementation, and continuous improvement, it aims to enhance maternity care and reduce unnecessary C-sections through collaborative efforts among healthcare providers and patients.
Encouraging trials of labor after previous C-sections (TOLAC) and fostering a multidisciplinary team approach in maternity care are crucial.
Regular training for healthcare providers and establishing supportive hospital policies further promote vaginal births.
Genetic deletion of HVEM in a leukemia B cell line promotes a preferential in...MARIALUISADELROGONZL
Introduction: A high frequency of mutations affecting the gene encoding Herpes
Virus Entry Mediator (HVEM, TNFRSF14) is a common clinical finding in a wide
variety of human tumors, including those of hematological origin.
Methods: We have addressed how HVEM expression on A20 leukemia cells
influences tumor survival and its involvement in the modulation of the antitumor
immune responses in a parental into F1 mouse tumor model of hybrid
resistance by knocking-out HVEM expression. HVEM WT or HVEM KO leukemia
cells were then injected intravenously into semiallogeneic F1 recipients and the
extent of tumor dissemination was evaluated.
Results: The loss of HVEM expression on A20 leukemia cells led to a significant
increase of lymphoid and myeloid tumor cell infiltration curbing tumor
progression. NK cells and to a lesser extent NKT cells and monocytes were the
predominant innate populations contributing to the global increase of immune
infiltrates in HVEM KO tumors compared to that present in HVEM KO tumors. In
the overall increase of the adaptive T cell immune infiltrates, the stem cell-like
PD-1- T cells progenitors and the effector T cell populations derived from them
were more prominently present than terminally differentiated PD-1+ T cells.
Conclusions: These results suggest that the PD-1- T cell subpopulation is likely
to be a more relevant contributor to tumor rejection than the PD-1+ T cell subpopulation. These findings highlight the role of co-inhibitory signals delivered
by HVEM upon engagement of BTLA on T cells and NK cells, placing HVEM/BTLA
interaction in the spotlight as a novel immune checkpoint for the reinforcement
of the anti-tumor responses in malignancies of hematopoietic origin.
Genetic deletion of HVEM in a leukemia B cell line promotes a preferential in...
Is Technology Removing the ‘Care’ from Healthcare?
1. A roundtable report based on the Topol Review
HEALTH
CARE?CARE?CARE?
IS TECHNOLOGY REMOVING THE ‘CARE’ FROM
2. IS TECHNOLOGY REMOVING THE ‘CARE’ FROM HEALTHCARE? 2
Healthcare has entered
the digital age
The digital era is transforming
healthcare. All stakeholders,
including pharma, will need to
adapt, finding new solutions to
meet evolving challenges and
opportunities. February’s Topol
Review offers useful pointers.
The inquiry, led by US cardiologist,
geneticist, and digital medicine
expert, Dr Eric Topol, explored
how to support the deployment
of digital healthcare technologies
throughout the NHS.
There are wide-reaching
implications for the industry.
With healthcare at this crossroads,
MSL Health convened a roundtable
discussion, consulting industry
leaders, including communications
executives, digital transformation
experts, marketing chiefs and
clinicians/clinical scientists to look
ahead to the NHS’s digital future
and the role of pharma within it.
HEALTHCARE IS ENTERING THE
DIGITAL AGEDIGITAL AGEDIGITAL AGEDIGITAL AGEDIGITAL AGEDIGITAL AGEDIGITAL AGEDIGITAL AGEDIGITAL AGE
The healthcare workforce
needs expertise and
guidance to evaluate
new technologies, using
processes grounded in
real-world evidence.
Patients need to be
included as partners
and informed about
health technologies,
with a particular
focus on vulnerable/
marginalised groups to
ensure equitable access.
The gift of time:
wherever possible
the adoption of new
technologies should
enable staff to gain
more time to care,
promoting deeper
interaction with patients¹.
1. https://www.hee.nhs.uk/our-work/topol-review
The three principles proposed
by the Topol Review
3. IS TECHNOLOGY REMOVING THE ‘CARE’ FROM HEALTHCARE?
QQQ
IS TECHNOLOGY REMOVING THE ‘CARE’ FROM HEALTHCARE? 3
The Topol Review calls for patients to
be included as partners, with a particular
focus on providing the same access to
vulnerable and marginalised groups.
It says the healthcare workforce should
have the expertise to maximise the benefits
from these new technologies. And staff
should, as a result, have more time to
care for and interact with patients. But
the pursuit of these principles raises key
questions for the pharmaceutical industry
given its core role in developing new
treatments – and its conspicuous absence
among the large number of stakeholders
who contributed to the report.
The roundtable focused
on three critical questions
to guide the discussion
Q.1
How do stakeholders ensure that vital
personalised care is supported in an
environment where remote interactions
with healthcare professionals are
becoming the norm?
Q.2
What is the solution to bridging the
‘digital divide’ to help prevent those
with limited access becoming further
marginalised?
Q.3
Where can the greatest benefit be
gained from the application of new
technologies such as genomics,
digital medicine, artificial intelligence
and robotics?
4. How do stakeholders ensure
that vital personalised
care is supported in an
environment where remote
interactions with healthcare
professionals are becoming
the norm?
Personalised care means people
have choice and control over
the way their care is planned
and delivered. It is based on
‘what matters’ to them and their
individual strengths and needs.
Today’s increasingly digital savvy
patients appear willing to embrace
new technology. Patients may
welcome a quicker way to get
health advice rather than going
to see a GP for a face to face visit.
Direct consultations with healthcare
professionals are already being
supplemented with video and
phone consultations.
Up to 30 per cent of the population
lives with two or more long-term
conditions². The increasingly
complex nature of chronic disease
management will make it even
more important for stakeholders
to communicate effectively with
each other. Digital tools can allow
time to be used more effectively
and care to be customised. Digital
technology might free up more
time for those who need personal
interaction with their clinicians,
while others could use an algorithm
and self-prescribe. There is some
evidence that algorithms can offer
sound advice. Empathy, though,
is conveyed differently across a
machine interface. Patients are
changing: the next generation
may not need or even expect face
to face engagement. This could
change even further with artificial
intelligence.
But is the pharma industry paying
enough attention to skilling patients
in communication for this new
digital world, or giving sufficient
thought on how it’s going to
reach them? The aim is to make
FACE-TO-FACEFACE-TO-FACEFACE-TO-FACEFACE-TO-FACEFACE-TO-FACEFACE-TO-FACEFACE-TO-FACEFACE-TO-FACE-TO-FACEFACE-TO-FACEFACE-TO-FACEFACE-TO-FACE
DIGITALDIGITALDIGITALDIGITALDIGITALDIGITALDIGITALFACE-TO-DIGITALFACE-TO-FACEDIGITALFACE-TO-FACE
VS
companies digitally focused,
with patient engagement upper-
most in everyone’s minds. Some
companies are trying to bridge the
gap. They are actively researching
digital solutions and mapping new
external stakeholders who might
get involved.
However, many in the industry
seem to think that there’s a long
way to go on communications
for digital change and using
digital channels.
IS TECHNOLOGY REMOVING THE ‘CARE’ FROM HEALTHCARE? 4
Q.1
2. https://richmondgroupofcharities.org.uk/taskforce-multiple-conditions
5. IS TECHNOLOGY REMOVING THE ‘CARE’ FROM HEALTHCARE? 5
Industry has to raise
its game in key areas
It needs to have more activities
that talk to patients and equip
them to make the most of access
to healthcare that doesn’t involve
a face-to-face meeting with their
GP. With greater preparedness,
big pharma will be in pole position
to help lift patient engagement
to the next phase, which some
have dubbed Health 5.0. This will
employ the latest digital tools
to boost the personalisation of
care. It recognises the core role
of patients as customers – going
well beyond patient-centric
healthcare towards customer-
centric wellbeing services.
EQUIPPING PATIENTS FOR
Patients are increasingly digitally
adept, embracing new technology
to engage with personalised
treatment plans. Making patients
strategic partners in their health
is fundamental to a new level of
engagement, better enabling them
to navigate the fast, disruptive
changes that are shaping the new
healthcare environment.
DIGITAL CAREDIGITAL CAREDIGITAL CAREDIGITAL CAREDIGITAL CAREDIGITAL CAREDIGITAL CARE
DIGITAL CARE
DIGITAL CAREDIGITAL CAREDIGITAL CARE
“PARTNERSHIPS
ARE THE KEY.
I DON’T BELIEVE THAT
PHARMA CAN DO
IT ON ITS OWN.”
6. CHANGINGCHANGINGCHANGINGCHANGINGCHANGINGCHANGINGCHANGING
DIGITAL CARE
CHANGINGCHANGINGCHANGING
THE RULESTHE RULESTHE RULESTHE RULESTHE RULESTHE RULESTHE RULES
DIGITAL CARE
THE RULESTHE RULESTHE RULES
What is the solution to
bridging the ‘digital divide’
to help prevent those with
limited access becoming
further marginalised?
Will the divide between the
technophiles and technophobes
– separated on the basis of age,
socio-economic class or simply
inclination – limit the spread of
these benefits? This raises another
pertinent question: how will we give
patients the skills – or even ensure
the degree of social involvement
– they need to make the most
of digital healthcare? It’s back to
reaching beyond the engaged
patient. People who welcome
digital healthcare – or even those
who tend to get involved in related
trials – are more digitally savvy;
in other words, a self-selecting
audience.
But what does the industry actually
know about customers and patients?
And is it in the position to bridge
the information technology gap in
healthcare? Big companies might
have 20 to 30 people talking to
clinicians every day; in future they
are likely to get their insights from
digital routes and tools.
New players will enter the market.
It is now easier for tech giants
to enter digital healthcare by
piggybacking on a smaller existing
health organisation, thanks to their
existing scale and infrastructure.
In the not so distant future we are
likely to see digital health platforms
by tech giants such as Apple or
Amazon which will integrate all
types of healthcare data – and help
consumers through predictive and
preventive care models.
There will always be a role for
pharmaceutical companies in
developing new medicines.
Regulation will be a huge issue for
the industry. Many stakeholders still
have to get to grips with the notion
of NHS and social care working
together. But there will need to
be big changes, particularly in
regulation if the pharma industry
is to play its part in boosting
public health in the digital age.
The burgeoning market in health
apps underlines this. Several
informants referred to the “wild west”
“IT’S ALL VERY WELL
HAVING AN OFFICIAL
MISSION STATEMENT TO
MAKE PATIENTS’ LIVES
BETTER. BUT IF WE’RE
GOING TO MOVE INTO
THE DIGITAL SPHERE
AND SUPPORT DECISION
MAKING TOOLS, WE
HAVE WORK TO DO.”
of half a million or so apps, with
many of the popular ones lacking
an evidence base, in comparison
to the high burden of proof for the
effectiveness of new medicines.
Q.2
IS TECHNOLOGY REMOVING THE ‘CARE’ FROM HEALTHCARE? 6
7. DIGITAL DIVIDEDIGITAL DIVIDEDIGITAL DIVDEDIGITAL DIVDEDIGITAL DIVDEDIGITAL DIVDEDIGITAL DIVDEDIGITAL DIVDE
The industry can currently
only communicate
with “other relevant
decision makers”
But in the new world who are
“relevant” decision makers?
Personalised medicine will thrust
this role onto patients. Yet industry
representatives can’t promote
medicine directly to the public,
or interact with social care – an
area that is increasingly seen as
indivisible from healthcare. It may
well be time to relax or revamp
those rules.
We can’t really predict what changes
will have occurred in 20 years’ time.
But the industry can and should
be proactive – and adapt to shape
the future for the benefit of all.
The importance of personalised
care needs to be considered
right at the beginning of the
development of a new treatment.
Pharma can and does engage
patients in the drug development
process with everything from
scientific discovery and drug
development, to disease
management and patient
education. But additional questions
will need to be asked as a matter of
routine. How is this treatment going
to be delivered to the patients? Is it
the type of medicine that will fit into
an algorithm? And in this case, how
do we design our clinical trials to
accommodate this?
There is much for the industry to
be positive about: it has a fantastic
history of public health campaigns
with patient groups and charities
in helping provide the expertise
and funds to make people aware of
things they might otherwise not be.
But to take this to the next level,
in the digital age, the industry will
have to champion digital tech for
patients, and let them know how it
can help them. Pharma reps might
not need to see 200 GPs because
an algorithm will tell them what to
prescribe. Instead, we could see
reps taking public health campaigns
to much larger consumer audiences
– for example, via football grounds.
The Topol Review calls for
programmes to engage and
educate the public on digital
healthcare technologies. To do
this, the NHS will have to develop
national industry exchange networks,
as well as opportunities for
clinicians to partner with academia
and the health tech industry.
IS TECHNOLOGY REMOVING THE ‘CARE’ FROM HEALTHCARE?
DIGITAL DIVIDEDIGITAL DIVIDEDIGITAL DIVIDEDIGITAL DIVIDEDIGITAL DIVDEDIGITAL DIVDEDIGITAL DIVDEDIGITAL DIVIDEDIGITAL DIVIDEDIGITAL DIVIDE
7
8. BETTER AND SAFER PERSONALISED
TREATMENTSTTREATMENTSTREATMENTSTREATMENTSTREATMENTSTREATMENTSTREATMENTSRARE DISEASESRARE DISEASE
Where can the greatest
benefit be gained from
the application of new
technologies such as
genomics, digital medicine,
artificial intelligence and
robotics?
Advances in everything from
earlier diagnosis to better and
safer personalised treatments
promise to revolutionise healthcare.
Breakthroughs in genomics,
computing and diagnostics
will allow clinicians to deliver
personalised, precision care
to patients.
Artificial intelligence – the branch
of computer science dealing with the
simulation of intelligent behaviour
in computers – is already beginning
to play a big role. A handful of
companies have developed
algorithms that are able to learn and
evolve as they gather information.
In April 2018, in a real first, the Food
and Drug Administration approved
IDx-DR, an imaging tool driven by
AI that detects diabetic retinopathy.
Trials for the automation of breast
screening are already underway.
Wearable technologies will allow
patients – and clinicians – to monitor
a range of vital signs, including
glucose levels, away from the clinic.
The Topol Review’s emphasis
on preventive medicine requires
genomics to play an ever-larger
role. But the rise of genomics could
leave a long ‘tail’ of rare genetic
conditions – and patients – at risk
of being forgotten. It’s relatively
easy designing personalised care
for vascular disease or diabetes.
Common diseases have engaged
sizeable patient organisations,
from which you can get input
or members of a steering group.
There is a challenge to do this
for rare diseases.
Financial dilemnas do exist and
these must be considered when
looking to maximise the benefits
of technological advances. The
crucial economic question: Is it the
industry’s job to pursue medical
research for the 1%, those who don’t
respond to existing treatments, the
long epidemiological ‘tail’?
Everyone agrees that someone
should do it. But, for this to be
financially viable, there will need
to be a fundamental change
in our approach to healthcare
economics. The benefits from
digital technology should provide
the incentive.
Technological advancements could
provide direct benefits for industry;
it might provide even more focused
R&D with greater efficiency and
savings. Digitalisation would see
pharma companies specialise more;
concentrating on doing fewer
things but doing them better.
Q.3
IS TECHNOLOGY REMOVING THE 'CARE' FROM HEALTHCARE? 8
9. The expert patient
is on the rise
And when it comes to digital
transformation, as with everything
else touched upon in the
roundtable discussion, patients
need to be included.
There is a fundamental need for
the industry to be involved in
digitalisation policy. The Topol
Review sought little or no industry
input and just one pharmacist was
involved in the whole report. Even
though the community pharmacist
is a key figure in patient access to
healthcare there was no discussion
in the report about their role and
how technological changes would
affect them. The ABPI hinted at
this disappointing lack of inclusion
by pointedly noting that digital
healthcare challenges would
be “most effectively addressed
through collaboration across NHS,
academia and industry”.
It is essential to ensure the right new
partnerships are forged with other
stakeholders (while acknowledging
that different companies have
different priorities and concerns).
It will be interesting to see what the
new NHS unit designed to oversee
digital transformation of the health
service, NHSX, will bring to the table³.
Rethinking our approach to clinical
trials in an era of personalised
medicines is unavoidable. This
will require a redesign of trial
methodology and reporting and
an increased reliance on open data
and evidence. This could bring
benefits in terms of increased
public trust.
Clear guidance on what standards
should apply to new technologies
would also be welcome - the Topol
Review appeared to suggest that
different rules might apply in future.
It may well be time to adjust or
revamp those rules.
And finally, digital transformation
will require embedding tech skills
throughout the pharma workforce.
The Topol Review cleverly models
future careers in healthcare
showing how our current roles will
change over the next decades; and
we can fully expect to see roles in
pharma changing too.
“PHARMA MUST ALWAYS
LISTEN TO PATIENTS.
WHEREVER THINGS
WE’VE DONE HAVE
BEEN WELL RECEIVED,
IT’S BEEN BECAUSE
WE PUT THE PATIENT
AT THE CENTRE – AND
WHEN WE DO THAT AND
WHEN WE DO IT WELL,
EVERYONE BENEFITS.”
CONCLUSIONCONCLUSIONCONCLUSIONCONCLUSIONCONCLUSIONCONCLUSIONCONCLUSIONCONCLUSIONCONCLUSIONCONCLUSIONCONCLUSION
9IS TECHNOLOGY REMOVING THE ‘CARE’ FROM HEALTHCARE?
3. https://www.gov.uk/government/news/nhsx-new-joint-organisation-for-digital-data-and-technology
10. IS TECHNOLOGY REMOVING THE ‘CARE’ FROM HEALTHCARE? 10
Contact Alison Dunlop,
Managing Director, Health at MSL
and join the conversation.
alison.dunlop@mslgroup.com
+44 (0)20 3219 8700
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