Description:
This presentation explores the innovative green synthesis methods of magnetic nanoparticles (MNPs) and their diverse applications in biology. It covers the synthesis techniques emphasizing environmental sustainability, the unique properties of MNPs, and their role in biomedical applications such as targeted drug delivery, imaging, and biosensing. The presentation also discusses challenges, future directions, and the potential impact of MNPs in advancing biotechnological and medical fields.
The document discusses magnetic nanoparticles (MNPs), which are nanoparticles that can be manipulated using magnetic fields. It describes various types of MNPs including ferrites, ferrites with a shell, metallic nanoparticles, and metallic nanoparticles with a shell. Common synthesis methods are also summarized, such as co-precipitation, microemulsion, thermal decomposition, and hydrothermal synthesis. Finally, potential applications of MNPs in biomedical imaging, cancer therapy, drug delivery, and other areas are highlighted.
This document summarizes a student project on the green synthesis of nanoparticles. It discusses various methods for synthesizing nanoparticles, emphasizing that green synthesis is more eco-friendly than physical or chemical methods as it does not require high temperatures, pressures, or toxic chemicals. The document then describes how plant extracts can be used to synthesize nanoparticles and the characterization techniques used to analyze the particles produced, including UV-vis spectroscopy, DLS, SEM, TEM and FTIR. It concludes by noting some applications of green-synthesized nanoparticles in fields such as medicine, environment and engineering.
The next years will prove the importance of greensynthesis methods for MNPs and MONPs production because they are not
only easy to execute, fast, and cheap but also less toxic and environmentally ecofriendly. Nanoparticle synthesis using microorganisms
and plants by green synthesis technology is biologically safe, cost-effective, and environment-friendly. Plants and microorganisms
have established the power to devour and accumulate inorganic metal ions from their neighboring niche. The biological entities are
known to synthesize nanoparticles bothextra and intracellularly. The capability of a living system to utilize its intrinsic organic
chemistry processes in remodeling inorganic metal ions into nanoparticles has opened up an undiscovered area of biochemical analysis.
Metal nanoparticles (MNPs) and metal oxidenanoparticles (MONPs) are used in numerous fields. The new nano-based entities are
being strongly generated and incorporated into everyday personal care products, cosmetics, medicines, drug delivery, and clothing
toimpact industrial and manufacturing sectors, which means that nanomaterials commercialization and nanoassisted device will
continuously grow. They can be prepared by many methods such as green synthesis and the conventional chemical synthesis methods.
The green synthesis of nanoparticles (NPs) using living cells is a promising and novelty tool in bionanotechnology. Chemical and
physical methods are used to synthesize NPs; however, biological methods are preferred due to its eco-friendly, clean, safe, cost
effective, easy, and effective sources for high productivity and purity. Greensynthesis includes infinite accession to produce MNPs and
MONPs with demanding properties. The structure–function relationships between nanomaterials and key information for life cycle
evaluation lead to the production of high execution nanoscale materials that are gentle and environmentally friendly. Majority of plants
have features as sustainable and renewable suppliers compared with microbes and enzymes, as they have the ability to pick up almost
75% of the light energy and transform it into chemical energy, contain chemicals like antioxidants and sugars, and play fundamental
roles in the manufacture of nanoparticles. Plants considered the main factory for the green synthesis of MNPs and MONPs, and until
now, different plant species have been used to study this, but the determined conditions should be taken into consideration to execute
this preparation.
This document discusses magnetic nanoparticles (MNPs) and their potential applications in anti-infective therapy. It describes several methods for synthesizing MNPs, including co-precipitation, microemulsion, thermal decomposition, hydro/solvothermal, chemical vapor deposition, and sol-gel. Common types of MNPs are ferrites, ferrites with shells, metallic nanoparticles with shells, and polymeric nanocomposites. Applications discussed include magnetic resonance imaging, drug delivery, biomedical uses, data storage, catalysis, separation techniques, solar cells, cell/gene therapy, and hyperthermia for cancer treatment.
Magnetic nano- and microparticles have been successfully used in many areas of algae biotechnology, especially for harvesting of algal biomass, separation of algal biologically active compounds, immobilization of algal cells, removal of important xenobiotics using magnetically modified algae.
This document discusses the green synthesis of nanoparticles using fruit peel for water purification. It begins with definitions of nanoparticles and green chemistry. It then describes different approaches to nanoparticle synthesis and explains why green synthesis is preferable to physical and chemical methods. The document reviews literature on nanoparticle synthesis using various fruit peels. It explains the mechanism of plant extract mediated nanoparticle synthesis and describes the preparation of peel extracts. Finally, it discusses applications of nanoparticles in water purification, factors affecting nanoparticle synthesis, and advantages of the green synthesis approach.
The document discusses the green synthesis of cerium oxide nanoparticles using turmeric powder. Cerium oxide nanoparticles were synthesized by adding cerium nitrate to an extract of turmeric powder boiled in water. The obtained nanoparticles were characterized through techniques such as XRD, PSA, SEM, TEM, and TG/DTA to determine properties like average crystallite size, particle size, morphology, structure and thermal stability. Key applications of cerium oxide nanoparticles include use in fuel cells, removing pollutants from diesel emissions, and glass polishing.
ZnO nanoparticles were synthesized using a combustion method with low-temperature solution combustion. XRD and SEM characterization confirmed the formation of hexagonal wurtzite ZnO nanoparticles around 30-40nm in size. The antibacterial activity of the ZnO nanoparticles was tested against E. coli using colony counting and disk diffusion methods. Both methods showed the ZnO nanoparticles had antibacterial effects in a concentration-dependent manner, with 100μg/L ZnO demonstrating the strongest antibacterial activity through over 70% bacterial reduction and the largest inhibition zone of 24mm. The ZnO nanoparticles were also found to damage the genomic DNA of treated E. coli cells.
Nanoparticles show potential for applications in plant pathology including detection and control of plant diseases. Zinc nanoparticles synthesized using Pseudomonas fluorescens were effective against Xanthomonas spp. that cause diseases in various crops. Smaller sulfur nanoparticles showed greater inhibition of the fungal pathogen Fusarium solani compared to larger nanoparticles. Silver-chitosan nanoparticles reduced gray mold disease in strawberries caused by Botrytis cinerea. Magnesium oxide nanoparticles induced systemic resistance in tomatoes against Ralstonia solanacearum and reduced bacterial wilt disease progression. Nanoparticles have potential for developing smart delivery systems to monitor and treat plant diseases.
This document discusses green synthesis of nanoparticles using biological methods. It describes how nanoparticles can be synthesized using plant extracts, agricultural waste, microorganisms and enzymes in an environmentally friendly way. This is advantageous over chemical and physical methods as it is cost-effective, produces non-toxic nanoparticles and does not require high temperature or pressure. Specific examples discussed include using bacteria to synthesize silver nanoparticles and controlling factors like pH and temperature to regulate nanoparticle size and shape during microbial synthesis. Overall, the document presents biological methods as a green alternative for nanoparticle production.
The document discusses biodegradable nanoparticles for drug delivery. Nanotechnology allows therapeutic agents to be delivered in biocompatible nanoparticles, nanocapsules, micellar systems, and conjugates. This enables targeted delivery of drugs to improve effects and stability. Polymer properties can be tailored to control drug release and provide optimal targeting. Nanoparticles use bio-specific ligands to direct them to target tissues. The review will focus on intracellular uptake, trafficking, and mechanisms of enhanced therapeutic efficacy of nanoparticle-encapsulated drugs.
Nanotechnology scope and application in plant pathology
This document discusses nanotechnology and its applications in plant pathology. It begins by defining nanotechnology as designing, producing and applying structures between 1-100 nm by controlling shape and size at the nanoscale. It then discusses various methods of synthesizing nanoparticles, including chemical, physical and biological methods. The document outlines several applications of nanoparticles in plant pathology, including for detecting plant diseases using nanoparticle-based sensors. It also discusses how nanoparticles like silver, chitosan, copper and silica can be used for managing plant diseases through their antifungal and antimicrobial properties. Several case studies on using nanoparticles like nanosilver and chitosan nanoparticles to inhibit fungal pathogens are also presented.
The document discusses nanocatalysts and their applications in chemical industry. It begins with definitions of catalyst and nanocatalyst. It then discusses different types of nanocatalysts including homogeneous nanocatalysts which are soluble in solvents and heterogeneous nanocatalysts which are insoluble. Methods for preparing both homogeneous and heterogeneous nanocatalysts are described. The document outlines several industrial applications of nanocatalysts such as in biodiesel production, water purification, drug delivery, and fuel cells. It concludes that nanocatalysts have advantages over traditional catalysts like high activity, selectivity, stability, and ease of separation.
Biological method for the preparation of nanoparticles(Sheersho)
This document discusses various biological methods for synthesizing nanoparticles, including using bacteria, fungi, yeast, plants, and waste materials. It describes how nanoparticles can be synthesized intracellularly or extracellularly by bacteria. Specific bacteria used to synthesize silver, gold, iron and other nanoparticles are mentioned. The document also discusses nanoparticle synthesis using fungi, yeasts, plant extracts, and industrial waste. It concludes by noting the promising potential but current limitations of biological nanoparticle synthesis for medical applications.
This document summarizes research on the green synthesis of nanoparticles using plants. It discusses how plants provide an eco-friendly alternative to physical and chemical synthesis methods. Key points include:
- Plants can synthesize nanoparticles both in the laboratory and natural environment through biosynthesis, involving the reduction of metal ions.
- Factors like temperature, pH, and ion concentrations can influence nanoparticle size, shape, and properties.
- Plants have synthesized various nanoparticles including silver, gold, silicon-germanium, and magnetite which have applications in areas like catalysis, sensing, and medicine.
- Silver nanoparticles from various plants have demonstrated antimicrobial properties against bacteria like E. coli, making them promising for applications like
This document presents a layout for a presentation on synthesizing and characterizing iron oxide nanoparticles. The presentation aims to develop an alternative green method for synthesizing iron oxide nanoparticles from locally available tea leaves and to investigate their antibacterial and antifungal properties. The experimental section describes synthesizing iron oxide nanoparticles from tea leaf extract and coating them with chitosan. Characterization techniques like SEM, XRD, and FTIR are used to analyze the nanoparticles. Antibacterial tests on E. coli and antifungal tests on Candida albicans show the coated nanoparticles have antibacterial and antifungal properties. The expected outcome is that the green synthesis method could be used to develop novel biomaterials and the nanoparticles could help treat
The document discusses magnetic nanoparticles (MNPs), which are nanoparticles that can be manipulated using magnetic fields. It describes various types of MNPs including ferrites, ferrites with a shell, metallic nanoparticles, and metallic nanoparticles with a shell. Common synthesis methods are also summarized, such as co-precipitation, microemulsion, thermal decomposition, and hydrothermal synthesis. Finally, potential applications of MNPs in biomedical imaging, cancer therapy, drug delivery, and other areas are highlighted.
This document summarizes a student project on the green synthesis of nanoparticles. It discusses various methods for synthesizing nanoparticles, emphasizing that green synthesis is more eco-friendly than physical or chemical methods as it does not require high temperatures, pressures, or toxic chemicals. The document then describes how plant extracts can be used to synthesize nanoparticles and the characterization techniques used to analyze the particles produced, including UV-vis spectroscopy, DLS, SEM, TEM and FTIR. It concludes by noting some applications of green-synthesized nanoparticles in fields such as medicine, environment and engineering.
The next years will prove the importance of greensynthesis methods for MNPs and MONPs production because they are not
only easy to execute, fast, and cheap but also less toxic and environmentally ecofriendly. Nanoparticle synthesis using microorganisms
and plants by green synthesis technology is biologically safe, cost-effective, and environment-friendly. Plants and microorganisms
have established the power to devour and accumulate inorganic metal ions from their neighboring niche. The biological entities are
known to synthesize nanoparticles bothextra and intracellularly. The capability of a living system to utilize its intrinsic organic
chemistry processes in remodeling inorganic metal ions into nanoparticles has opened up an undiscovered area of biochemical analysis.
Metal nanoparticles (MNPs) and metal oxidenanoparticles (MONPs) are used in numerous fields. The new nano-based entities are
being strongly generated and incorporated into everyday personal care products, cosmetics, medicines, drug delivery, and clothing
toimpact industrial and manufacturing sectors, which means that nanomaterials commercialization and nanoassisted device will
continuously grow. They can be prepared by many methods such as green synthesis and the conventional chemical synthesis methods.
The green synthesis of nanoparticles (NPs) using living cells is a promising and novelty tool in bionanotechnology. Chemical and
physical methods are used to synthesize NPs; however, biological methods are preferred due to its eco-friendly, clean, safe, cost
effective, easy, and effective sources for high productivity and purity. Greensynthesis includes infinite accession to produce MNPs and
MONPs with demanding properties. The structure–function relationships between nanomaterials and key information for life cycle
evaluation lead to the production of high execution nanoscale materials that are gentle and environmentally friendly. Majority of plants
have features as sustainable and renewable suppliers compared with microbes and enzymes, as they have the ability to pick up almost
75% of the light energy and transform it into chemical energy, contain chemicals like antioxidants and sugars, and play fundamental
roles in the manufacture of nanoparticles. Plants considered the main factory for the green synthesis of MNPs and MONPs, and until
now, different plant species have been used to study this, but the determined conditions should be taken into consideration to execute
this preparation.
This document discusses magnetic nanoparticles (MNPs) and their potential applications in anti-infective therapy. It describes several methods for synthesizing MNPs, including co-precipitation, microemulsion, thermal decomposition, hydro/solvothermal, chemical vapor deposition, and sol-gel. Common types of MNPs are ferrites, ferrites with shells, metallic nanoparticles with shells, and polymeric nanocomposites. Applications discussed include magnetic resonance imaging, drug delivery, biomedical uses, data storage, catalysis, separation techniques, solar cells, cell/gene therapy, and hyperthermia for cancer treatment.
Magnetic particles in algae biotechnology iqraakbar8
Magnetic nano- and microparticles have been successfully used in many areas of algae biotechnology, especially for harvesting of algal biomass, separation of algal biologically active compounds, immobilization of algal cells, removal of important xenobiotics using magnetically modified algae.
This document discusses the green synthesis of nanoparticles using fruit peel for water purification. It begins with definitions of nanoparticles and green chemistry. It then describes different approaches to nanoparticle synthesis and explains why green synthesis is preferable to physical and chemical methods. The document reviews literature on nanoparticle synthesis using various fruit peels. It explains the mechanism of plant extract mediated nanoparticle synthesis and describes the preparation of peel extracts. Finally, it discusses applications of nanoparticles in water purification, factors affecting nanoparticle synthesis, and advantages of the green synthesis approach.
The document discusses the green synthesis of cerium oxide nanoparticles using turmeric powder. Cerium oxide nanoparticles were synthesized by adding cerium nitrate to an extract of turmeric powder boiled in water. The obtained nanoparticles were characterized through techniques such as XRD, PSA, SEM, TEM, and TG/DTA to determine properties like average crystallite size, particle size, morphology, structure and thermal stability. Key applications of cerium oxide nanoparticles include use in fuel cells, removing pollutants from diesel emissions, and glass polishing.
ZnO nanoparticles were synthesized using a combustion method with low-temperature solution combustion. XRD and SEM characterization confirmed the formation of hexagonal wurtzite ZnO nanoparticles around 30-40nm in size. The antibacterial activity of the ZnO nanoparticles was tested against E. coli using colony counting and disk diffusion methods. Both methods showed the ZnO nanoparticles had antibacterial effects in a concentration-dependent manner, with 100μg/L ZnO demonstrating the strongest antibacterial activity through over 70% bacterial reduction and the largest inhibition zone of 24mm. The ZnO nanoparticles were also found to damage the genomic DNA of treated E. coli cells.
Nanoparticles show potential for applications in plant pathology including detection and control of plant diseases. Zinc nanoparticles synthesized using Pseudomonas fluorescens were effective against Xanthomonas spp. that cause diseases in various crops. Smaller sulfur nanoparticles showed greater inhibition of the fungal pathogen Fusarium solani compared to larger nanoparticles. Silver-chitosan nanoparticles reduced gray mold disease in strawberries caused by Botrytis cinerea. Magnesium oxide nanoparticles induced systemic resistance in tomatoes against Ralstonia solanacearum and reduced bacterial wilt disease progression. Nanoparticles have potential for developing smart delivery systems to monitor and treat plant diseases.
This document discusses green synthesis of nanoparticles using biological methods. It describes how nanoparticles can be synthesized using plant extracts, agricultural waste, microorganisms and enzymes in an environmentally friendly way. This is advantageous over chemical and physical methods as it is cost-effective, produces non-toxic nanoparticles and does not require high temperature or pressure. Specific examples discussed include using bacteria to synthesize silver nanoparticles and controlling factors like pH and temperature to regulate nanoparticle size and shape during microbial synthesis. Overall, the document presents biological methods as a green alternative for nanoparticle production.
Biodegradable Nanoparticles For Drug DeliveryAmber Wheeler
The document discusses biodegradable nanoparticles for drug delivery. Nanotechnology allows therapeutic agents to be delivered in biocompatible nanoparticles, nanocapsules, micellar systems, and conjugates. This enables targeted delivery of drugs to improve effects and stability. Polymer properties can be tailored to control drug release and provide optimal targeting. Nanoparticles use bio-specific ligands to direct them to target tissues. The review will focus on intracellular uptake, trafficking, and mechanisms of enhanced therapeutic efficacy of nanoparticle-encapsulated drugs.
Nanotechnology scope and application in plant pathologyEr. Ahmad Ali
This document discusses nanotechnology and its applications in plant pathology. It begins by defining nanotechnology as designing, producing and applying structures between 1-100 nm by controlling shape and size at the nanoscale. It then discusses various methods of synthesizing nanoparticles, including chemical, physical and biological methods. The document outlines several applications of nanoparticles in plant pathology, including for detecting plant diseases using nanoparticle-based sensors. It also discusses how nanoparticles like silver, chitosan, copper and silica can be used for managing plant diseases through their antifungal and antimicrobial properties. Several case studies on using nanoparticles like nanosilver and chitosan nanoparticles to inhibit fungal pathogens are also presented.
The document discusses nanocatalysts and their applications in chemical industry. It begins with definitions of catalyst and nanocatalyst. It then discusses different types of nanocatalysts including homogeneous nanocatalysts which are soluble in solvents and heterogeneous nanocatalysts which are insoluble. Methods for preparing both homogeneous and heterogeneous nanocatalysts are described. The document outlines several industrial applications of nanocatalysts such as in biodiesel production, water purification, drug delivery, and fuel cells. It concludes that nanocatalysts have advantages over traditional catalysts like high activity, selectivity, stability, and ease of separation.
Biological method for the preparation of nanoparticles(Sheersho)Sheersha Pramanik 🇮🇳
This document discusses various biological methods for synthesizing nanoparticles, including using bacteria, fungi, yeast, plants, and waste materials. It describes how nanoparticles can be synthesized intracellularly or extracellularly by bacteria. Specific bacteria used to synthesize silver, gold, iron and other nanoparticles are mentioned. The document also discusses nanoparticle synthesis using fungi, yeasts, plant extracts, and industrial waste. It concludes by noting the promising potential but current limitations of biological nanoparticle synthesis for medical applications.
Different types of methods can be used for the preparation of Magnetic Nanoparticles, their advantages and disadvantages and applications of the materials in various fields are given in the presentation
Biomedical applications of nanoparticlesSwathi Babu
This document discusses the biomedical applications of nanoparticles. It begins by defining nanoparticles as particles between 1-100 nanometers in size. It then outlines several types of nanoparticles that have biomedical applications, including gold nanoparticles, quantum dots, iron oxide nanoparticles, carbon nanotubes, dendrimers, and lipid-based nanoparticles. For each type of nanoparticle, it provides examples of their biomedical uses such as drug delivery, cancer treatment, biomedical imaging, and diagnosis. It also discusses considerations for the toxicity of nanoparticles and their potential effects on cells and animals. In closing, it covers antimicrobial nanoparticles and their use against bacteria, fungi, and viruses.
Similar to Green Synthesis of Magnetic Nanoparticles and Their Biological application.pptx (20)
Risks & Business Risks Reduce - investment.pdfHome
In this presentation, I have shown major risks that are to face in a business investment. Also I have shown their classification and sources.
This information have taken from my text book -" Investment Analysis and Portfolio Management ~chapter 2 Investment~ " For complete this Presentation I used Figma and Canva.
My Role:
a. Student Final year - Accounting
b. Presentation Designer
Destyney Duhon personal brand explorationminxxmaree
Destyney Duhon embodies a singular blend of creativity, resilience, and purpose that defines modern entrepreneurial spirit. As a visionary at the intersection of artistry and innovation, Destyney fearlessly navigates uncharted waters, sculpting her journey with a profound commitment to authenticity and impact.This Brand exploration power point is a great example of her dedication to her craft.
A study on drug utilization evaluation of bronchodilators using DDD methodDr. Afreen Nasir
The abstract was published as a conference proceeding in a Newsletter after being presented as an e-posture and secured 2nd prize during the scientific proceedings of "National Conference on Health Economics and Outcomes Research (HEOR) to Enhance Decision Making for Global Health" held at Raghavendra Institute of Pharmaceutical Education and Research (RIPER)- Autonomous in association with the International Society for Pharmacoeconomics and Outcomes Research (ISPOR)-India Andhra Pradesh Regional Chapter during 4th& 5th August 2023.
Nasir A. A study on drug utilization evaluation of bronchodilators using the DDD method. RIPER - PDIC Bulletin ISPOR India Andhra Pradesh Regional Chapter Newsletter [Internet]. 2023 Sep;11(51):14. Available from: www.riper.ac.in
Call India AmanTel allows you to call from any country in the world including India to the USA and Canada at the cheapest rate Limited offers new users some free minutes.
stackconf 2024 | On-Prem is the new Black by AJ JesterNETWAYS
In a world where Cloud gives us the ease and flexibility to deploy and scale your apps we often overlook security and control. The fact that resources in the cloud are still shared, the hardware is shared, the network is shared, there is not much insight into the infrastructure unless the logs are exposed by the cloud provider. Even an air gap environment in the cloud is truly not air gapped, it’s a pseudo-private network. Moreover, the general trend in the industry is shifting towards cloud repatriation, it’s a fancy term for bringing your apps and services from cloud back to on-prem, like old school how things were run before the cloud was even a thing. This shift has caused what I call a knowledge gap where engineers are only familiar with interacting with infrastructure via APIs but not the hardware or networks their application runs on. In this talk I aim to demystify on-prem environments and more importantly show engineers how easy and smooth it is to repatriate data from cloud to an on-prem air gap environment.
stackconf 2024 | Buzzing across the eBPF Landscape and into the Hive by Bill ...NETWAYS
The buzz around the Linux kernel technology eBPF is growing quickly and it can be hard to know where to start or how to keep up with this technology that is reshaping our infrastructure stack. In this talk, Bill will trace how he got into eBPF, explore some of the applications leveraging eBPF today, and teach others how to dive into the hive of activity around eBPF. People just beginning with eBPF will learn how eBPF makes it possible to have efficient networking, observability without instrumentation, effortless tracing, and real-time security (among other things) without needing your own kernel team. Those already familiar with eBPF will get an overview of the eBPF landscape and learn about many new and expanding eBPF applications that allow them to harness the power without needing to dive into the bytecode. The audience will walk away with an understanding of the buzz around eBPF and knowledge of new tools that may solve some of their problems in networking, observability, and security.
stackconf 2024 | Using European Open Source to build a Sovereign Multi-Cloud ...NETWAYS
The European Commission has clearly identified open source as a strategic tool for bringing some balance to an EU cloud market currently dominated by a handful of non-EU hyperscalers. Part of that commitment comes through a series of ambitious, multi-million EU projects like the SIMPL platform for Data Spaces and the multi-country “Important Project of Common European Interest on Next Generation Cloud Infrastructure and Services” (IPCEI-CIS). For the first time in the history of the European Union, it is the EU industry who will be leading large-scale open source projects aimed at building European strategic technologies. In this talk we will explain in detail how specific European open source technologies are being brought together as part of some of those projects to start building Sovereign Multi-Cloud solutions that ensure interoperability and digital sovereignty for European users while preventing vendor lock-in in the cloud market, opening up competition in the emerging 5G/edge.
stackconf 2024 | Using European Open Source to build a Sovereign Multi-Cloud ...
Green Synthesis of Magnetic Nanoparticles and Their Biological application.pptx
1. GREEN SYNTHESIS OF MAGNETIC NANOPARTICLES
AND THEIR BIOLOGICALAPPLICATIONS
PRESENTED BY: AHMEDSAEED
SUPERVISED BY: PROFESSORDR.AKRAMRAZA
1
2. Types of Magnetic Nanoparticles
TEM-images-of-cobalt-ferrite--NPs
FE-SEM images: (a, b) for CoFe2O4 samples
and (c, d) for NiFe2O4 samples
Iron Oxide Nanoparticles
Magnetite (Fe3O4)
Maghemite (γ-Fe2O3)
Metallic Nanoparticles
Iron (Fe)
Cobalt (Co)
Alloy Nanoparticles
Iron-Platinum (FePt)
Cobalt-Platinum (CoPt)
Ferrite Nanoparticles
Nickel Ferrite (NiFe2O4)
Cobalt Ferrite (CoFe2O4)
2
3. Properties of Magnetic Nanoparticles
Super-Paramagnetism:
No remnant magnetization.
Surface Functionalization:
Modifiable for specific uses.
Biocompatibility:
Safe for biological systems.
Chemical Stability:
Resistant to oxidation and degradation.
Thermal Stability:
Maintains properties under varying temperatures.
3
4. Introduction to Green Synthesis
Definition
Biological Organisms:
Use of plants, microbes, enzymes.
Origins
Eco-friendly chemical production reducing harmful substances.
Developed for sustainable and safe chemical processes.
Core Principles
Uses renewable resources.
Safer solvents and conditions.
Reduces waste and energy use.
Significance
Promotes sustainability and safety.
Supports global pollution reduction efforts.
Applications
Pharmaceuticals, nanotechnology, agriculture.
4
5. Why Green Synthesis?
Renewable Resources:
Use of natural, sustainable materials.
Energy Efficiency:
Often requires lower energy input.
Biocompatibility:
Produces non-toxic nanoparticles.
Public Health:
Safer for researchers and consumers.
Regulatory Compliance:
Easier to meet environmental regulations.
Sustainability:
Utilizes renewable resources.
Cost-effectiveness:
Often more economical.
5
7. Plant Extracts in Synthesis
Neem (Azadirachta indica)
Widely used for synthesizing silver and gold nanoparticles.
Contains bioactive compounds like azadirachtin.
Tea (Camellia sinensis)
Rich in polyphenols and antioxidants.
Effective in producing stable gold and silver nanoparticles.
Eucalyptus (Eucalyptus globulus)
High concentration of essential oils.
Used in synthesizing a variety of metal nanoparticles.
Banana (Musa paradisiaca)
Contains reducing sugars and phenolic compounds.
Utilized for the synthesis of silver and gold nanoparticles.
Mango (Mangifera indica)
Rich in flavonoids and phenolic compounds.
Effective in producing gold nanoparticles.
Hibiscus (Hibiscus rosa-sinensis)
Contains anthocyanins and flavonoids.
Used for synthesizing silver nanoparticles.
7
8. Microbial Synthesis
Bacteria
Examples: Pseudomonas aeruginosa, Bacillus subtilis.
Role: Act as reducing agents to convert metal ions to nanoparticles.
Fungi
Examples: Aspergillus niger, Fusarium oxysporum.
Role: Secrete enzymes and proteins that facilitate nanoparticle synthesis.
Algae
Examples: Chlorella vulgaris, Spirulina platensis.
Role: Utilize photosynthesis to reduce metal ions to nanoparticles.
Yeasts
Examples: Saccharomyces cerevisiae, Candida utilis.
Role: Produce bioactive molecules that aid in nanoparticle formation.
Actinomycetes
Examples: Streptomyces spp., Nocardia spp.
Role: Produce extracellular enzymes for nanoparticle synthesis.
Mechanism
Process: Metal ions are reduced to nanoparticles by microbial metabolites.
Stabilization: Microbial proteins and enzymes cap and stabilize nanoparticles.
8
9. Enzymatic Processes
Introduction to Enzymatic Synthesis
Utilizes enzymes as catalysts for eco-friendly production of
metal nanoparticles, offering precise control over size and
shape.
Types of Enzymes Used
Enzymes like oxidoreductases (e.g., peroxidases) and lyases (e.g., phytases)
are employed for their ability to reduce metal ions and stabilize resulting
nanoparticles.
Mechanism of Enzymatic Reduction
Enzymes facilitate reduction reactions, converting metal ions into
nanoparticles by controlling nucleation and growth processes.
Advantages of Enzymatic Synthesis
Benefits include biocompatibility, operation under mild conditions (neutral
pH, room temperature), and the avoidance of harsh chemicals typically used
in conventional methods.
9
10. Case Study: Tea Extract Synthesis
Process:
Iron oxide nanoparticles synthesized using tea extract.
Results:
High yield, good magnetic properties.
Advantages:
Simple, cost-effective, eco-friendly.
Applications:
Drug delivery, MRI contrast agents.
10
11. Advantages of Microbial Synthesis
Eco-friendly:
Uses natural microorganisms.
Scalability:
Potential for large-scale production.
Specificity:
Genetically engineered for specific synthesis.
Biocompatibility:
Produces non-toxic nanoparticles.
Efficiency:
High yield under optimized conditions.
Research Focus:
Enhancing microbial synthesis pathways
11
12. Case Study: Bacterial Synthesis (magnetotactic bateria)
Metal Ion Uptake:
Bacteria absorb metal ions like Fe(II) and Fe(III) from their
surroundings.
Intracellular Transformation:
Enzymatic reduction converts absorbed ions to ferrous (Fe2+)
and then ferric (Fe3+) forms inside the cell.
Nucleation of Nanoparticles:
Ferric ions nucleate within magnetosomes, specialized cell
compartments.
Crystal Growth and Maturation:
Nanoparticles grow and crystallize into magnetite or greigite
under protein control.
Biomineralization Control:
Proteins regulate nanoparticle size, shape, and magnetic
properties.
12
13. Biological Applications of MNPs
Drug Delivery:
Targeted delivery using magnetic fields.
Hyperthermia Treatment:
MNPs generate heat to kill cancer cells.
Magnetic Resonance Imaging (MRI):
Contrast agents for improved imaging.
Biosensors:
Detection of biomolecules for diagnostics.
Environmental Applications:
Removal of pollutants from water.
Tissue Engineering:
Scaffold design and regenerative medicine.
13
14. Drug Delivery Systems
Mechanism:
MNPs loaded with drugs can be directed to specific sites using
magnetic fields.
Benefits:
Targeted therapy, reduced side effects.
Controlled Release:
Precise delivery of therapeutic agents.
Biocompatibility:
Safe for use in vivo.
Examples:
Chemotherapeutics, antibiotics.
14
15. Biosensors
Mechanism:
MNPs functionalized with specific biomolecules for detecting pathogens or
biomarkers.
Applications:
Diagnostics, environmental monitoring, food safety.
Advantages:
High sensitivity, rapid detection.
15
16. Hyperthermia Treatment
Mechanism: MNPs
generate heat when exposed to an alternating magnetic field.
Application:
Localized heating to kill cancer cells.
Advantages:
Minimally invasive, precise targeting.
Challenges:
Controlling temperature and avoiding damage to healthy tissue.
Research:
Optimizing MNPs for maximum heat generation.
Clinical Trials:
Exploring effectiveness in various cancer types.
16
17. MRI Contrast Agents
Mechanism:
MNPs improve contrast in MRI scans.
Beznefits:
nhanced imaging of tissues and organs.
Applications:
Diagnosis of diseases, monitoring treatment progress.
Advantages:
High contrast, biocompatibility.
Challenges:
Ensuring long-term stability and safety.
Research:
Developing MNPs with specific targeting abilities.
17
18. Environmental Applications
Mechanism:
MNPs used to remove pollutants like heavy metals from water.
Benefits:
Effective, reusable, eco-friendly.
Applications:
Water purification, soil remediation.
Advantages:
High efficiency, low cost.
Future Directions:
Developing MNPs for specific pollutants.
18
19. Challenges in Green Synthesis of
Magnetic Nanoparticles
Control over Particle Size and Morphology
struggle to achieve precise control over the size and morphology of magnetic
nanoparticles.
This variability can affect their magnetic properties and application suitability.
Scalability
At industrial scale efficiency and cost effectiveness remain a challenge
Stability and Shelf Life:
exhibit lower stability or shorter shelf life compared to their conventionally synthesized
counterparts
Surface Functionalization and Biocompatibility:
adequate surface functionalization without compromising their green nature and
biocompatibility is a significant challenge.
19
20. Future Directions
Enhancing Efficiency and Scalability
Develop improved, efficient and scalable green synthesis methods
Exploring Novel Green Resources
Investigate new bioresources and waste mate
Functionalization and Surface Engineering:
Develop methods for precise surface functionalization
Integration with AI and Computational Approaches
Utilize artificial intelligence (AI) and computational modeling to accelerate the design
and optimization of green synthesis methods.
Collaborative Research and Knowledge Sharing:
Foster interdisciplinary collaborations between chemists, biologists, engineers, and
environmental scientists to advance knowledge sharing and innovation in green
synthesis technologies.
20
21. To My Guiding Star
This presentation is dedicated to
The Legend Behind My Success,
Sir Dr Prof. AKRAM RAZA.
whose unwavering guidance and support
have been the foundation of my success.
Your inspiration and encouragement mean
the world to me.
The Architect of My Accomplishments,
Pictured Here!
21