All Questions
Tagged with amines amino-acids
5
questions
2
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answers
527
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Why is the lysine side chain more basic?
As per PubChem: $pK_1 = 2.18$; $pK_2 = 8.95$; $pK_3 = 10.53$ at 38 °C, indicating that the side chain amino group is deprotonated at a higher pH, indicating it is more basic. I tried to justify this ...
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3
votes
1
answer
54
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Will ethyl 2-amino-1H-imidazole-5-carboxylate undergo ester aminlysos with the primary amines of bPEI efficiently in methanol?
I was about to set up the following reaction, but before I do, I wanted to see if anyone has some suggestions or thinks this will not work:
24mmol Nboc protected ethyl 2-amino-1H-imidazole-5-...
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5
votes
1
answer
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Synthesizing octopine from arginine and 2-bromopropionic acid
I am a biologist, and organic chemistry lessons are a distant memory now. I am interested in synthesizing a small amount of octopine. Octopine is a natural molecule resulting from an enzyme-catalyzed ...
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0
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0
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Resonance structure with allylic lone pair
Draw the appropriate resonance structure for 5-aminolevulinic acid:
As there is an allylic lone pair, my first arrow goes from the lone pair to form a π-bond, and the second goes from the π-bond to ...
2
votes
1
answer
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Histidine vs Lysine
Among the amino acids, histidine and lysine, which is more basic?
And why?
I tried protonating and checking electronic effects but couldn't reach a satisfactory conclusion.
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