From my understanding polyphonics are a single instruments ability to play two or more notes concurrently (at the same time). Therefore a singer’s voice is considered monophonic and not polyphonic because the singer can only reproduce one audible voice at a time. More examples of monophonic instruments include trumpet or a trombone. Many synthesizers are only capable of monophonic playback being able to play sound from only one depressed key on the keyboard at a time and at any given point in time regardless of how many keys are depressed at the same given point in time. If a voice is to be reproduced synthetically with the sampler on a polyphonic synthesizer, it then can support multiple playback of the audible voice.
Now a grand piano is considered polyphonic because you can play multiple notes at the same time like playing a cord or triad. Stringed instruments would be considered polyphonic to a degree because a musician are capable of playing two strings at the same time with one bow. Guitars are also polyphonic capable. Many other synthesizer keyboards support polyphonic playback so that capable of playing multiple audible notes at the same time mimicking an analog piano's polyphonic abilities.
As far as homophonics are concerned , YourDictionary describes -
The definition of homophonic is having one sound or line of melody at a time that >is played by multiple instruments at the same time, or two words that are >pronounced the same but differ in their meanings.
An example of something homophonic is a piece of music with chords, where two >instruments play the same line of melody in the same rhythm; however, one >instrument plays one note and a second instrument places a note in harmony.
An example of homophonic words are pair and pear.
I’ll quickly summaries that homophonics are the act of an instrument playing in unison or harmony with another or other instruments.
Another example of the latter definition of homophony are the difference of the two words won, and one. – they both are words that mean two different things, but, homo-phonetically audibly sound the same as if they were the same word.
Therefore two or more polyphonic or monophonic instruments vs. a homophonic instrument or instruments can be played in homophonetic unison and in harmony. These instruments playing in unison are not exactly considered to be playing in polyphony.
These answers should satisfy the initial question even if whatever notes being played sound out of tune or out of harmony. :)