Genetics

In a finding that vastly expands the understanding of tumor evolution, researchers discover genetic biomarkers that can predict the breast cancer subtype a patient is likely to develop.

Researchers studied hundreds of Bengal cats to uncover the genetic origins of their leopard-like patterns and found that their appearance stems largely from domesticated cats.

Stanford Medicine researchers and their colleagues tracked the gut, mouth, nose and skin bacteria of 86 people for as long as six years to try to gauge what constitutes a healthy microbiome.

Research throws light on the mystery of why women are much more prone to autoimmune disorders: A molecule made by one X chromosome in every female cell can generate antibodies to a woman’s own tissues.

The team led by Stanford Medicine analyzed thousands of genomes, including those newly sequenced from 204 skeletons, to gain insight into how and where people moved during the Roman Empire.

Circulating tumor DNA predicts recurrence and splits disease into two subgroups in Stanford Medicine-led study of Hodgkin lymphoma. New drug targets or changes in treatments may reduce toxicity.

Changes to short, repetitive sequences in the genome have been linked to diseases like autism and schizophrenia. New revelations about how such changes increase and decrease gene expression may provide insight into these and other disorders.

Two professors are named Innovation Investigators, and four win Ignite Awards.

A massive study of medical and genetic data shows that people with a particular version of a gene involved in immune response had a lower risk of Alzheimer’s and Parkinson’s disease.

The tumor suppressor p53 has been in the limelight for decades. But its cancer-fighting function may be only a side effect of its role in tissue repair, a Stanford Medicine study finds.

Human cells evolving in the laboratory undergo a series of predictable, sequential genetic changes that lead to pre-cancer. Blocking these changes may allow intervention before cancer occurs.