First, observe that
$$\sum_{k=1}^n \frac{1}{k^5} = \zeta(5) - \sum_{k=n+1}^\infty \frac{1}{k^5}.$$
However, by an argument similar to the one used in the proof of the integral test,
$$0 < \sum_{k=n+1}^\infty \frac{1}{k^5} < \int_n^\infty \frac{dx}{x^5} = \frac{1}{5 n^4}.$$
Therefore, if we let $a_n := n \sum_{k=1}^n \frac{1}{k^5}$, then
$$n \zeta(5) - \frac{1}{5 n^3} < a_n < n \zeta(5).$$
However, at this point, if we try to get an approximation of $\{ a_n \}$ using the above approximation of $a_n$, then we run into the issue that the fractional part function is discontinuous at integers, so $\{ a_n \}$ and $\{ n \zeta(5) \}$ could be different by almost one when $a_n$ is close to an integer. To get around this, I will use the fairly standard trick of using the function $x \mapsto e^{2\pi i x}$ from $\mathbb{R}$ to the unit circle $S^1$ in the complex plane; this function is continuous and is closely related to the fractional part function. (Alternatively, if you're comfortable with the topological group $\mathbb{R} / \mathbb{Z}$, then you could instead use the projection map $\mathbb{R} \to \mathbb{R} / \mathbb{Z}$.)
Thus, from the above inequalities, it is straightforward to conclude that $a_{n+1} - a_n \to \zeta(5)$ as $n \to \infty$; as a result, $e^{2\pi i a_{n+1}} / e^{2\pi i a_n} \to e^{2\pi i \zeta(5)}$ as $n \to \infty$. However, since $1 < \zeta(5) < 2$, $\zeta(5)$ is not an integer, so $e^{2\pi i \zeta(5)} \ne 1$. That implies that the sequence $e^{2\pi i a_n}$ cannot be convergent.
On the other hand, $e^{2\pi i a_n} = e^{2\pi i \{ a_n \}}$. Therefore, if we had $\lim_{n\to \infty} \{ a_n \} = L$, we would have $e^{2\pi i a_n} \to e^{2\pi i L}$ as $n\to \infty$, giving a contradiction to the previous paragraph. We can thus conclude that $\{ a_n \}$ also is not a convergent sequence.