There are plenty of resources out there explaining how to align multiple lines of equations at the equals sign. But I can’t find anything that says when this should be done. Does any style guide, ISO standard, or similar publication address this?
Use cases I’ve seen include:
One equation spanning multiple lines, e.g. $$ \begin{align} 0 &= x^2 - 4x + 4 \\ &= (x - 2)^2 \end{align} $$
The next line is derived from the previous one, e.g. $$ \begin{align} 0 &= (x - 2)^2 \\ \therefore x &= 2 \end{align} $$
The equations are a list of formulas, identities, etc. given together, e.g. $$ \begin{align} d &= 2r \\ C &= 2\pi r \\ \mathrm{Area} &= \pi r^2 \end{align} $$
The lines are a system of equations, to be solved or otherwise treated together, e.g. $$ \begin{align} 2x &+ 4y &= 4 \\ x &+ y &= 3 \end{align} $$
(I would think that #3 is done because it looks tidy, whereas #1 and #2 are about continuity between lines, and #4 is more general related-ness. But that’s just my impression.)
I’m intentionally leaving out inequalities, by the way. They have their own issues.