The pairs of primes $(p,q)$ with $p\le q\le 10^5$ such that $p^3+q^3$ is a perfect square , are (the last entry is the maximum possible exponent of the perfect power $p^3+q^3$ which is only different from $2$ in the first example) :
? forprime(a=1,10^5,forprime(b=a,10^5,c=ispower(a^3+b^3);if(c>0,print([a,b,c])))
)
[2, 2, 4]
[11, 37, 2]
[1801, 56999, 2]
[2137, 8663, 2]
[6637, 86291, 2]
[8929, 28703, 2]
[44111, 48817, 2]
[57241, 87959, 2]
?
Are there infinitely many pairs of primes $(p,q)$ such that $p^3+q^3$ is a perfect square?
For fixed $p$, only finitely many $q$ can exist such that the required property holds, but neverhteless infinitely many pairs could exist. Maybe properties of elliptic curves could help solve the question.