Divide the two numbers and prove the result is grater or less than 1. Then, respectively, the first number or the second number is bigger than the other one.
This is my first post here, so I hope somebody will help me with the proper formatting, but generally its like this:
$$
\frac{1000^{1000}}{1001^{999}} =
\frac{1}{1001}\cdot \frac{1000^{1000}}{1001^{1000}} =
\frac{1}{1001}\cdot \left( \frac{1000}{1001}\right)^{1000}
$$
As you can see here:
$\frac{1}{1001} < 1$ and $(1000/1001)^{1000} < 1$, so $1000^{1000}/1001^{999} < 1$
So from here we can conclude that
$1000^{1000} < 1001^{999}$