All Questions
Tagged with amines reactivity
6
questions
2
votes
0
answers
121
views
Can alkyl halides react with guanidine/guanidino groups?
I wonder how the π delocalization of guanidino groups affects the reactivity of the terminal nitrogens with respect to alkyl halides compared to, say, primary amines?
- 183
6
votes
1
answer
5k
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Selectivity of diazo-coupling with p-amino phenol
I came across this question and I've been thinking about it since, without being able to find a convincing major product. This question is related to one I found on this site, Diazo Coupling reaction ...
- 1,169
5
votes
2
answers
6k
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Reaction of amines with diethyl oxalate (Hofmann amine separation method)
Why does only one molecule of secondary amine react with diethyl oxalate and two molecules of primary amine react with diethyl oxalate?
I feel secondary amine also should have reacted similar to ...
- 2,209
4
votes
1
answer
2k
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Is there any reaction between amines and AgNO3?
I found a question in a book about the reaction between $\ce{AgNO3}$ and aromatic/aliphatic amines, but I couldn't find any information about
it. What should be the expected reaction mechanism and ...
- 283
2
votes
0
answers
290
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Primary amine versus phosphoramidate reactivity with succinate esters
I have posted two reactions below. The top reaction is well known and occurs readily and near quantitatively (e.g. in protein modification), while the bottom reaction to my knowledge does not exist in ...
- 991
22
votes
4
answers
8k
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Why do Organolithium or Grignard reagents act as nucleophiles and not as bases with aldehydes and ketones
I've read entire Chapter 14: Organometallic Compounds of Francis Carey's "Organic Chemistry" but I still didn't get an answer to my question.
Quote from the book:
Because of their basicity ...
- 963