Molecular hydrogen biomed-applications-888
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molecular hydrogen is a very simple yet never yet commercialized regenerative medicine agent. My patent seeks to create the economic infrastructure to support a broad range of applications based upon a solid base of evidence for efficacy as an anti-aging tool.
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Molecular hydrogen biomed-applications-888
- 1. Molecular Hydrogen “An idea and pharmaceutical whose time has come” a food and nutraceutical ….
- 2. Molecular Hydrogen “An idea whose time has come” History Historical applications: -Dirigible-until the Hindenberg Incident -Hydrogenation of oil-until vascular incidents -Inert and non toxic-useless in biomedical -Industrial gas for welding, petroleum refining, and industrial chemical engineering -No historical medical uses prior to 1976
- 3. Molecular Hydrogen “An idea whose time has come” The paradigm shifts First hint of useful bio-activity:
- 4. Molecular Hydrogen “An idea whose time has come” Early roadblocks -Fyfe and Dole publish in AAAS “Science” -University sees hyperbaric hydrogen as insurance liability ,“a bomb”, and orders apparatus to be deconstructed. -No interest by medical or private industry to put molecular hydrogen into any product pipeline -Inertness of molecular hydrogen questioned
- 5. Molecular Hydrogen “An idea whose time has come” Safety to humans established -Molecular hydrogen finds application in diving gas mixtures -Still considered inert and biomedically useless -Safe long term use established….GRAS
- 6. Molecular Hydrogen “An idea whose time has come” hyperbaric H2 physiological effects
- 7. Molecular Hydrogen “An idea whose time has come” hyperbaric H2- 3 decades after seminal paper
- 8. Molecular Hydrogen “An idea whose time has come” Hydrogen water -Spas market special spring waters as therapeutic -H2 levels at homeopathic levels of 4-6 ppm -Easily dismissed as a mineral water with an added placebo effect -Investigation begins to separate fact from fancy
- 9. Molecular Hydrogen “An idea whose time has come” Fringe medicine publishes data
- 10. Molecular Hydrogen “An idea whose time has come” Explosion of interest begins
- 11. Fig.?1 Illustration of the generation and scavenging systems of reactive oxygen species (ROS) in mitochondria. Superoxide radical anions (<ce:glyph name="rad"/> O<ce:inf loc="post"> 2</ce:inf> <ce:sup loc="post"> ?</ce:sup> ) are generated by the... Shigeo Ohta Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases Biochimica et Biophysica Acta (BBA) - General Subjects Volume 1820, Issue 5 2012 586 - 594 http://dx.doi.org/10.1016/j.bbagen.2011.05.006
- 39. Molecular Hydrogen “An idea whose time has come” Future directions -Hydrogen water at 4-6ppm has benefits -Lactulose produces H2 in gut but benefits are skewed by poor bioavailability and catabolism by other microflora -Inhaled H2 poses explosion hazards to dwellings, requires contracts and specialized equipment
- 40. Molecular Hydrogen “An idea whose time has come” Future directions -What if there were a simple way to increase bioavailabilty with no need for dispensing equipment or hazards of explosive gases? -What if the delivery mode was marketable as food or food supplement that would slowly diffuse molecular hydrogen into body fluids, lungs and tissues of all descriptions?
- 41. Molecular Hydrogen “An idea whose time has come” Future directions INVENTOR : JOHNSON , MORRIS, F. , whose complete address is of SW34-01-16-W2, BOX 10, BEAUBIER , SASKATCHEWAN , CELL PHONE 701-240-9411, email lifespan.pharma.inc@gmail.com CANADA Method to use a stable foam composed of bubbles of various food/ supplement/ cosmetic/ pharmaceutical substances to increase the bio-availability of otherwise inert molecular hydrogen gas for medically useful health maintenance , health promotion, anti-aging and generalized disease process interference purposes in biological living systems in a manner which manages regulatory and insurance risks and impediments to mass commercialization.
- 42. Molecular Hydrogen “An idea whose time has come” Future directions
- 43. Molecular Hydrogen “An idea whose time has come” Future directions
- 44. Molecular Hydrogen “An idea whose time has come” Future directions -With the protection of a pending patent would a modest amount of capital launch products and be easily scaleable with contract manufacturing and find distribution channels? -Would capital partner invest to expand the IP package to include beverages and cosmeceuticals and nutraceuticals?
- 45. Molecular Hydrogen “An idea whose time has come” Future directions -Proposed manufacturing at Food Centre and POS pilot plant in Saskatoon , Saskatchewan -Business offices in Saskatoon and Lake Alma , Saskatchewan -Equity and royalty swap for risk capital. Morris Johnson, SW34-01-16W2, Box 10 Beaubier, Sk., Canada, 701-240-9411 Lifespan.pharma.inc@gmail.com