Extended Data Fig. 8: Augmented muscle afferents restore neuromodulation of biomimetic response to perturbation. | Nature Medicine

Extended Data Fig. 8: Augmented muscle afferents restore neuromodulation of biomimetic response to perturbation.

From: Continuous neural control of a bionic limb restores biomimetic gait after amputation

Extended Data Fig. 8

a, With varying levels of residual muscle afferents for CTL and AMI cohorts, the modified swing kinematics during obstacle crossing and stance kinetics during a recovery step are plotted as: non-biomimetic (n = 3 CTL), low level (n = 3 CTL), and high level (n = 4 AMI) (bolded lines, mean; shaded regions, SEM). Resulting from the augmented residual muscle afferents, note the emerging neuromodulated biomimetic swing kinematics for obstacle crossing and stance kinetics during the recovery step. b, All subjects’ bionic perturbation response metrics are plotted against their agonist-antagonist muscle afferents. Pearson correlations (\(r\)), 95% CI, and slopes (m) are reported (n = 10, *P < 0.046, **P < 0.0089).

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