Charlie Moad

Greater Indianapolis Contact Info
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Experience & Education

  • Salesloft

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Publications

  • Identification of similar regions of protein structures using integrated sequence and structure analysis tools.

    BMC Structural Biology

    Understanding protein function from its structure is a challenging problem. Sequence based approaches for finding homology have broad use for annotation of both structure and function. 3D structural information of protein domains and their interactions provide a complementary view to structure function relationships to sequence information. We have developed a web site http://www.sblest.org/ and an API of web services that enables users to submit protein structures and identify statistically…

    Understanding protein function from its structure is a challenging problem. Sequence based approaches for finding homology have broad use for annotation of both structure and function. 3D structural information of protein domains and their interactions provide a complementary view to structure function relationships to sequence information. We have developed a web site http://www.sblest.org/ and an API of web services that enables users to submit protein structures and identify statistically significant neighbors and the underlying structural environments that make that match using a suite of sequence and structure analysis tools. To do this, we have integrated S-BLEST, PSI-BLAST and HMMer based superfamily predictions to give a unique integrated view to prediction of SCOP superfamilies, EC number, and GO term, as well as identification of the protein structural environments that are associated with that prediction. Additionally, we have extended UCSF Chimera and PyMOL to support our web services, so that users can characterize their own proteins of interest.

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Projects

  • TourML

    - Present

    TourML was created to serve as a simple and portable representation for tour content. Having a common language for this content will enable content management systems, kiosks, and mobile applications to speak a common language. Additionally, users of TourML will be better positioned to share and sustain their content no matter how the technology that we use to deliver these tours changes.

    Other creators
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  • TAP iOS

    - Present

    TAP for iOS is an open source, TourML driven application that facilitates mobile tours.

    Other creators
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  • TAP iOS

    - Present

    TAP for iOS is an open source, TourML driven application that facilitates mobile tours.

    Other creators
    See project
  • TAP

    - Present

    TAP is an open source suite of tools for providing mobile tours for museums

    Other creators
    See project
  • Matplotlib

    matplotlib is a python 2D plotting library which produces publication quality figures in a variety of hardcopy formats and interactive environments across platforms. Personal contributions include the original CocoaAgg driver and ellipse spline implementation.

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  • GLEWpy

    GLEWpy aims to bring advanced OpenGL extensions to Python. This allows the Python OpenGL developer to use features such as fragment/vertex shaders and image processing on the GPU. It serves as a compliment to PyOpenGL and toolkits such as GLUT and SDL.

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