At work we travel frequently. Finding the appropriate deals is always a balance between saving time and saving money. Booking through corporate travel agencies is often the most time efficient way of booking tickets. BUT they are often quite expensive, and the biggest downside of these agencies is their flexibility. They usually sell the most flexible tickets, but that is where the flexibility ends. Don't expect them to be flexible in terms of different modes of transports (parking at airport, trains, ferries, venue locations, etc). That is also something you cannot expect from them.
The alternative is that you start booking yourself. Doing it yourself gives you the best flexibility in syncing the itinerary with your personal schedule. But then you end up in a mess trying to make sense of the different airfares and possibilities. Sites like rome2rio go a long way, but travel agents always seem to have more insight in the options.
Is it possible and does it makes sense to become a "travel agent" for a small business, ngo, or any group that can't afford to let all its employees travel business class? If so, how can you become a travel agent yourself, not to make a living out of it, but to be able to have better insight in fares and issue your own tickets?
CAVEAT: I edited the question, the answers given show that I gave the impression that I wanted to start a business, I have no intention to do so, I merely want to have access to the same resources as a travel agent.