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0 votes
0 answers
15 views

Use of multiple comparison correction and composite DV

I am investigating the effect of a single X on a composite DV, Y. I want to also investigate the effect of X on the 36 sub-components of Y. Thus, I would have to run 37 multiple regression models, ...
taylor's user avatar
  • 1
0 votes
0 answers
31 views

GLM Multiple Comparisons

I am performing several Generalized Linear Models in my analysis and I am wondering which method to use for adjusting p-values due to multiple comparisons. I have 4 outcomes (judgement of intensity ...
KayAnn's user avatar
  • 11
3 votes
1 answer
195 views

Perform the multiple comparisons after controlling other covariates

To describe this issue, we consider the following 2 models: m1 <- lm(disp ~ drat, mtcars) m2 <- lm(disp ~ drat + factor(cyl), mtcars) ...
user18894435's user avatar
0 votes
0 answers
22 views

How to design contrasts for a three way mixed effect model with interactions?

I have an experiment which comprise a numerical dependent variable, say a feature such as growth_rate, and three independent factor variables describing where the samples were collected, i.e. locality,...
gabt's user avatar
  • 207
4 votes
1 answer
248 views

Adjusting p-values in multiple regression using permutation test

I have run a multiple regression model using a set of 10 categorical and numerical explanatory variables. This model results in 10 coefficients and their associated p-values. I would like to report ...
lmb8's user avatar
  • 43
7 votes
3 answers
1k views

Why is a "Correction" Required in Multiple Hypothesis Testing?

Suppose I have the following dataset that contains measurements on different patients (each unique ID is a unique patient) - "x" variables represent covariates and "y" variables ...
stats_noob's user avatar
1 vote
0 answers
32 views

Can multiple regression be used to test individual hypotheses?

In the linked article here Rubin proposes that familywise error correction is not necessary when the hypotheses are either that all tests will be significant ('conjunction testing') or that a series ...
llewmills's user avatar
  • 2,043
1 vote
0 answers
38 views

Question on Multiple Regression (vs multiple single regression models)

I have a pretty basic psychology fMRI study and we're trying to identify brain areas correlated with performance on a specific task. We have one dependent variable, and measurements for each brain ...
Justin Kasowski's user avatar
2 votes
1 answer
349 views

Is it necessary to correct p-values for multiple comparisons in multivariate regression?

In this suspiciously brief comment on another article, the author suggests that analysts should only correct for multiple comparisons in univariate regression when the predictor has more than two ...
llewmills's user avatar
  • 2,043
0 votes
1 answer
952 views

FDR Adjusted p value after multiple regression with categorical predictor with many levels

I would like to run a multiple linear regression to test if my protein of interest differs among different stages of a disease, while controlling for covariates/ confounders such as age and gender. ...
MQ99's user avatar
  • 23
3 votes
0 answers
68 views

Do you adjust p values at each test or after all tests completed?

Using several separate generalized additive models, do I adjust p-values after each one, or after all models? ...
CanyonView's user avatar
0 votes
1 answer
136 views

Understanding regression bootstrap confidence interval in multiple comparison

Let's say I have 100 subjects split into two age groups (young/older) and each have a single value given for performance on a memory test. I plot a linear regression for each age group, to test if ...
CanyonView's user avatar
0 votes
1 answer
124 views

Appropriate way to adjust p values for multiple comparisons of unrelated domains?

Our dataset has 325 participants. Within each participant, we are looking at how 3 brain regions (ROIs) in each hemisphere (so right and left separately) are correlated with 10 cognitive domains. ...
CanyonView's user avatar
1 vote
0 answers
47 views

Adjust for multiple comparisons in multiple linear regression with upstream model selection step

Say I have two DV y1 and y2, and three IV x1, x2, ...
msfrn's user avatar
  • 33
0 votes
1 answer
136 views

Feature Importance for each class when p>>n

I have a bioinformatics-related dataset with ~10k rows and ~100k columns (features) and a single response variable with roughly 25 classes. I want to figure out which of the features are useful in ...
m55667's user avatar
  • 51

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