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Questions tagged [dunnett]

Dunnett's test is a multiple comparison procedure for comparing a sngle control group with many comparison groups.

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Dunnett's test for comparisons with Control - how to conduct ANOVA for 2 factors, as well as adjusting for different experimental designs?

From what I understand, before we conduct Dunnett's test for comparisons of treatments to a Control, we have to do ANOVA. However, for a 2-factor experiment, there seem to be a lot of problems to me. ...
MD P's user avatar
  • 53
3 votes
1 answer
35 views

Significant results from ANOVA post-hoc Tukey's, insignificant with welch-ANOVA post-hoc Dunnett's T3

I performed one-way ANOVA tests with post-hoc Tukey's to look at multiple comparisons and got highly significant results, but noticed the $F$-value on the ANOVA was high. The SDs in the groups were ...
Harry's user avatar
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1 vote
0 answers
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balanced and unbalanced dose response experiments

Consider a dose response study where there are four active treatments (from the highest dose and lowest dose) and also a control. One goal is to test the hypothesis that treatments are more effective ...
user13154's user avatar
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6 votes
1 answer
386 views

multicomp package and emmeans package produce different adjust pvalues for Dunnett procedure [closed]

For Dunnett adjustment, multicomp package and emmeans package in R give different results. Anyone knows why? Thanks. Please see ...
user13154's user avatar
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0 votes
0 answers
26 views

What is the best post-hoc test to use after a two-way anova has shown there is only a significant effect when including 0 as a factor level?

I have two factors: A and B, and a response, y. For factor A I have 3 levels: 300,400,500. For factor B I have 3 levels: 0.5, 0.6, 0.7. I carried out an experiment with each combination of these two ...
Noah Sprent's user avatar
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0 answers
148 views

Is it possible to perform a comparison to a control group with a non-parametric post-hoc test in R?

Is it possible to perform a comparison to a control group with a non-parametric post-hoc test in R? I am familiar with various post-hoc tests such as Dunn and Conover, but I'm not sure how to ...
Julien Sade's user avatar
1 vote
1 answer
355 views

Equivalent to Dunnett's test for binomial endpoint?

I have a trial comparing 2 treatments vs a control group. Typically one would use Dunnett's test for this situation, but the outcome measure is binomial. It seems strange to me but I've looked for ...
Bosley's user avatar
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0 answers
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Does it make any difference to analyse change from baseline (observational study) or post-hoc contrast post vs. baseline?

I have an observational, non-randomized longitudinal study with 3 time point + baseline (t0 ... t3). Analysing solely the post-values in such trials is meaningless. I want to analyze the change from ...
Saronaya's user avatar
2 votes
1 answer
3k views

Dunn test and specific comparisons

What I need is a non-parametric alternative for Dunnett test to compare several groups with a control group (not all pairwise comparisons). And I realise that a specialised test is more appropriate ...
lapotok's user avatar
  • 23
0 votes
1 answer
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Is the "mvt" (using the multivariate t distribution) accepted way of adjusting for multiple comparisons when reporting to journals?

I use the awesome package multcomp and emmeans in R. These are the places I heard about the "mvt" method for the first time. And, however, it is what it's actually done in the Dunnett or ...
GibbsSampler10's user avatar
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1 answer
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Is there any measure of Effect Size for differences assessed with Dunnett method?

I know I could use the effect size pairwise, but I have a longitudinal data, where subjects were measures multiple times and there exists ICC > 0.5. I guess the pooled SD may be altered by this ...
Arianella's user avatar
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1 answer
35 views

Should I choose single model A+B+A:B or two models A at 2 levels of B?

I have a longitudinal model: response ~ device * time. The device should lower the response over time. There are two devices: A and B. There is an interaction between the device and time. The problem ...
Katikarnata's user avatar
1 vote
0 answers
98 views

Do I have to correct for multiplicity twice if I re-run a comparison with one more hypothesis during incremental testing?

Let's say I have a set of hypotheses ordered in time. These are about comparison to some baseline moment: $H_{t1 vs. baseline}$, $H_{t2 vs. baseline}$, $H_{t3 vs. baseline}$, ... I have 10 time ...
Gerard's user avatar
  • 11
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0 answers
756 views

How is the classic Dunnett test, with strict assumptions, related to Dunnett comparisons run on a top of very liberal models, like GLM or GEE?

As far as I understand, the classic Dunnett test is based on the t-test, applied multiple times to all comparisons vs. control and then corrected. So the assumptions of the Dunnett test must agree ...
Kazakh's user avatar
  • 1
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0 answers
854 views

How is the classic Dunnett test, with strict assumptions, related to Dunnett comparisons run on a top of very liberal models, like GLM or GEE?

As far as I understand, the classic Dunnett test is based on the t-test, applied multiple times to all comparisons vs. control and then corrected. So the assumptions of the Dunnett test must agree ...
Kazakh's user avatar
  • 1

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