From what we see in Star Trek, first contacts are very important dealings. So, my question is which ship 1 has made the most number of first contacts?
Allow me to define 'first contacts'. For the Enterprise NX-01, I define a first contact as a meeting with an alien species that humans had not previously made official contact with (for example, the meeting with the Klingons in the second episode would count as a first contact). For the Enterprise 1701 and 1701-D, and Voyager, these must be species that the Federation has not yet encountered.
1: By ship, I'm restricting it to the Enterprises NX-01, NCC-1701 and NCC-1701-D and Voyager, as they're likely to have made the most on-screen.