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Why would Macron humiliate himself, and France, to answer to Russian agitprop? Zelensky isn't in a situation where he can allow any doubts like that to get in the way of Ukraine aid - not at all the same circumstances. Why bother asking this Q?
FYI, decades ago, in a presidential debate: "Chirac: Mr. President, can you tell me today's exchange rate to the Deutschmark?". "Mitterand: Sir, I am the President of France. You are not my schoolmaster". By and large, IIRC French public opinion agreed that Chirac had overreached himself by trying to ambush bad-on-economics Mitterand - who likely had no clue - and that he had infringed on the dignity of the president's office. It would a major faux-pas for any head of state to stoop down to taking a drug test for such a ridiculous reason.
At least we seem to know why we're getting this anti-Macron prop right now from that corner. Macron apparently turned hardline anti-Putin recently bbc.com/news/world-europe-68575251