To answer in terms of electric circuits, we know that electric field $\bf E$ is related to the electrical potential $V$ by
$${\bf E}=-{\bf \nabla} V$$
That means that a positively charged particle in a region with varying potential will experience a force pointing towards regions of lower potential (and a negatively charged particle will experience a force towards higher potentials). In either case we'd describe the result as a current from higher potential to lower potential.
But, it's not correct to say current always flows from high potential to low potential. Every circuit must include some current flowing from high potential to low potential, and some current flowing from low potential to high potential, in order to form a complete circuit. The circuit elements through which current flows from high to low potential consume electrical energy, converting it to some other form (or storing it temporarily). And the circuit elements through which current flows from low to high potential deliver electrical energy to the rest of the circuit, either converting it from some other form (as in a generator or battery) or releasing energy previously stored (as in a capacitor or inductor discharging).
In other systems, there are analogous processes of flow in both directions. For example, water only flows downhill (from higher to lower gravitational potential) because it previously was evaporated by solar energy and was transported to the higher potential region as water vapor and rain.