Let $p,q$ and $r$ be positive integers. A Brieskorn sphere is a closed oriented $3$-manifold defined by $$\Sigma(p,q,r) = \{ x^p+y^q+z^r=0 \} \cap S^5.$$
Its fundamental group is well-known due to Milnor. It is always a rational homology sphere. When $p,q$ and $r$ are further chosen pairwise coprime, then it is an integral homology sphere.
In this case, the plumbing graph of a Brieskorn sphere is well-understood, see for example Section 1 of Saveliev's book: Invariants of Homology 3-Spheres.
One needs to find unique integers $b,p',q',r'$ solving the equation \begin{equation} bpqr+p'qr+pq'r+pqr'=-1 \end{equation} where $1\leq p' \leq p-1$, $1\leq q' \leq q-1$ and $1\leq r' \leq r-1$. It is basically done by taking mod of these integers.
How about the rational case? Is it possible to find a unique representation for the plumbing graph associated to Brieskorn spheres?