Jump to content

VSIG1

From Wikipedia, the free encyclopedia
VSIG1
Identifiers
AliasesVSIG1, 1700062D20Rik, GPA34, dJ889N15.1, V-set and immunoglobulin domain containing 1
External IDsOMIM: 300620; MGI: 1926039; HomoloGene: 12703; GeneCards: VSIG1; OMA:VSIG1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001170553
NM_182607

NM_026103
NM_030181
NM_001359143

RefSeq (protein)

NP_001164024
NP_872413

NP_080379
NP_084457
NP_001346072

Location (UCSC)Chr X: 108.04 – 108.08 MbChr X: 139.81 – 139.84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

V-set and immunoglobulin domain containing 1 is a protein that in humans is encoded by the VSIG1 gene.[5]

Function

[edit]

This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in a normal stomach and testis, as well as in gastric, esophageal, and ovarian cancers. Alternatively spliced transcript variants, encoding different isoforms, have been found for this gene. [provided by RefSeq, Dec 2009].

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000101842Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031430Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: V-set and immunoglobulin domain containing 1". Retrieved 2018-09-09.

Further reading

[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.