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NDUFV3

From Wikipedia, the free encyclopedia
NDUFV3
Identifiers
AliasesNDUFV3, CI-10k, CI-9KD, NADH:ubiquinone oxidoreductase subunit V3
External IDsOMIM: 602184; MGI: 1890894; HomoloGene: 10885; GeneCards: NDUFV3; OMA:NDUFV3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001001503
NM_021075

NM_001083891
NM_030087

RefSeq (protein)

NP_001001503
NP_066553

NP_001077360
NP_084363

Location (UCSC)Chr 21: 42.88 – 42.91 MbChr 17: 31.74 – 31.75 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial is an enzyme that in humans is encoded by the NDUFV3 gene.[5][6]

The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000160194Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024038Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ de Coo RF, Buddiger P, Smeets HJ, van Oost BA (Feb 1998). "Molecular cloning and characterization of the human mitochondrial NADH:oxidoreductase 10-kDa gene (NDUFV3)". Genomics. 45 (2): 434–7. doi:10.1006/geno.1997.4930. hdl:1765/57339. PMID 9344673.
  6. ^ a b "Entrez Gene: NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa".

Further reading

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