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HS6ST2

From Wikipedia, the free encyclopedia
HS6ST2
Identifiers
AliasesHS6ST2, heparan sulfate 6-O-sulfotransferase 2, MRXSPM
External IDsOMIM: 300545; MGI: 1354959; HomoloGene: 9277; GeneCards: HS6ST2; OMA:HS6ST2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001077188
NM_147175
NM_001394073
NM_001394074
NM_147174

NM_001077202
NM_001290467
NM_001290468
NM_015819

RefSeq (protein)

NP_001070656
NP_671704

NP_001070670
NP_001277396
NP_001277397
NP_056634

Location (UCSC)Chr X: 132.63 – 132.96 MbChr X: 50.48 – 50.77 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Heparan sulfate 6-O-sulfotransferase 2 is a protein that in humans is encoded by the HS6ST2 gene. [5]

Function

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Heparan sulfate proteoglycans are ubiquitous components of the cell surface, extracellular matrix, and basement membranes, and interact with various ligands to influence cell growth, differentiation, adhesion, and migration.

This gene encodes a member of the heparan sulfate (HS) sulfotransferase gene family, which catalyze the transfer of sulfate to HS. Different family members and isoforms are thought to synthesize heparan sulfates with tissue-specific structures and functions. Multiple transcript variants encoding different isoforms have been found for this gene.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171004Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000062184Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Heparan sulfate 6-O-sulfotransferase 2". Retrieved 2016-07-11.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.