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DDX24

From Wikipedia, the free encyclopedia
DDX24
Identifiers
AliasesDDX24, DEAD-box helicase 24
External IDsOMIM: 606181; MGI: 1351337; HomoloGene: 10702; GeneCards: DDX24; OMA:DDX24 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020414

NM_001159502
NM_020494
NM_001364162
NM_001364163

RefSeq (protein)

NP_065147

NP_001152974
NP_065240
NP_001351091
NP_001351092

Location (UCSC)Chr 14: 94.05 – 94.08 MbChr 12: 103.37 – 103.39 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ATP-dependent RNA helicase DDX24 is an enzyme that in humans is encoded by the DDX24 gene.[5][6]

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial RNA splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level.[6]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000089737Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041645Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zhao Y, Yu L, Fu Q, Chen W, Jiang J, Gao J, Zhao S (Sep 2000). "Cloning and characterization of human DDX24 and mouse Ddx24, two novel putative DEAD-Box proteins, and mapping DDX24 to human chromosome 14q32". Genomics. 67 (3): 351–5. doi:10.1006/geno.2000.6255. PMID 10936056.
  6. ^ a b "Entrez Gene: DDX24 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24".

Further reading

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