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Cdc42 binding protein kinase beta

From Wikipedia, the free encyclopedia
CDC42BPB
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCDC42BPB, MRCKB, CDC42 binding protein kinase beta, CHOCNS
External IDsOMIM: 614062; MGI: 2136459; HomoloGene: 55945; GeneCards: CDC42BPB; OMA:CDC42BPB - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006035

NM_183016

RefSeq (protein)

NP_006026
NP_006026.3

NP_898837

Location (UCSC)Chr 14: 102.93 – 103.06 MbChr 12: 111.26 – 111.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CDC42 binding protein kinase beta is a protein that in humans is encoded by the CDC42BPB gene. [5]

Function

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This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rats suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198752Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021279Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: CDC42 binding protein kinase beta". Retrieved 2017-05-31.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.