Jump to content

Angelicin synthase

From Wikipedia, the free encyclopedia
Angelicin synthase
Identifiers
EC no.1.14.13.115
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Angelicin synthase (EC 1.14.13.115, CYP71AJ4 (gene)) is an enzyme with systematic name (+)-columbianetin,NADPH:oxygen oxidoreductase.[1] This enzyme catalyses the following chemical reaction:

(+)-columbianetin + NADPH + H+ + O2 angelicin + NADP+ + acetone + 2 H2O

Angelicin synthase is a P450 monooxygenase enzyme.

References

[edit]
  1. ^ Larbat R, Hehn A, Hans J, Schneider S, Jugdé H, Schneider B, Matern U, Bourgaud F (February 2009). "Isolation and functional characterization of CYP71AJ4 encoding for the first P450 monooxygenase of angular furanocoumarin biosynthesis". The Journal of Biological Chemistry. 284 (8): 4776–85. doi:10.1074/jbc.M807351200. PMID 19098286.
[edit]