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Domestication had long-range consequences for the animals themselves; the very nature of the animals changed throughout the process — typically not in the animals’ favor. Through domestication, once-wild animals become increasingly more dependent on humans, physically and emotionally. Because a handful of traits (such as curiosity, lack of fear, willingness to try new things, food begging, submissiveness, etc.) found among the juveniles of a species are those selected in domestication, the physical traits of the young (shorter faces, excess fat, smaller brains, smaller teeth, etc.) will also be selected. This leads to modern domesticates that are physically and behaviorally unable to live independently and that are, in fact, perpetual juveniles. Once humans began selectively breeding their animal charges to emphasize or discourage certain physical or behavioral traits, the animals changed even further. Today, domesticates are, for the most part, smaller (yet fleshier), more brightly colored, with shorter faces, and rounder skulls. In addition, domestication has resulted in a permanent loss of genetic diversity within the species.

What's the exact menaing of the word 'charges'?

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    It's the animals in their charge (the animals they look after, that they're charged with supervising, keeping safe). More often used of children. Commented Jul 3 at 12:24
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    ... charge - full OED definition II.10.c (1596–) A person (typically a child), animal, or thing entrusted to someone's care. Commented Jul 3 at 12:29
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    Please edit to show that you've looked up "charge" (noun) in a dictionary, what you found, and what questions remain. Right now the only answer is to point you to the dictionary, but you might have new questions after checking it that would get you better answers. Voting to close and downvoting. Commented Jul 3 at 13:24
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    It's not surprising you didn't find it; Merriam-Webster gives about 50 usages and only one is this one! Commented Jul 3 at 13:50
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    What Merriam-Webster does say is that a charge is “a person or thing committed into the care of another.” One can scan even large definitions in a dictionary and find the one that makes sense in one’s context. Commented Jul 3 at 13:54

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