My boards are built in the US in batches of 200 each month. The PCBs are arrayed with routed tabs. All components (SMT and throughole) are on one side.
Throughole connectors (and other throughole parts) are placed by hand. So, we have to pay more for the the assembly of throughole components, compared to SMT components (the latter are placed with automatic pick&place). After placement, the throughole components are wave soldered all at once.
In my case, I was able to streamline the circuit board for assembly.
In some cases it may not be possible (for example, due to tight mechanical constraints), and some components would need to be soldered by hand.
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Related blog posts: Overhangs, Where to put panel tabs.
[I'm not affiliated with Screaming Circuits.]