Octet®- Affinity, Binding Kinetics and Concentration

Octet®- Affinity, Binding Kinetics and Concentration

Biotechnologieforschung

Goettingen, Niedersachsen 3.819 Follower:innen

Label-Free, Stress-Free Solutions for Drug Discovery and Biologics

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At this channel, we want to focus on label-free biomolecular interaction analysis such as protein-protein or protein-drug interactions. We will keep you updated on the newest developments and most exciting trends in the field, technical details and performance of our Octet® platform. We at Sartorius believe that listening to our customers, discussions with and among users are a key component to deliver innovative products that continually offer higher data quality to improve the outcomes of life science research and development projects. Furthermore, it helps us to understand the diverse landscape of laboratories on a global scale. Therefore, we would highly encourage you to engage with us in lively discussions. Therapeutic proteins, monoclonal antibodies (mAbs), bispecific antibodies (bsAbs), and antibody-drug conjugates (ADCs) are all large complex molecules that require reliable in-depth binding characterization and robust concentration determination of active analyte or impurities such as host cell protein (HCP). On the other hand, screening and characterizing small drug molecules is equally important. Octet® instruments eliminate many of the common issues associated with detailed characterization of binding and functional activities. The platform leverages proprietary Bio Layer Interferometry (BLI) technology, which uses optical biosensors to measure molecular interactions in parallel, without the use of detection agents. This robust and fluidics-free approach for direct measurement even in complex mixtures and unpurified samples enables an enviable variety of applications throughout biologics development from early selection to validation to manufacturing to QC. It is a precise and efficient means of collecting a wide range of information related to affinity, binding kinetics, analyte concentration, bio-similarity, specificity, potency, and selectivity of molecular binding. Follow us today to stay updated. The path to progress just got simpler.

Website
https://www.sartorius.com/en/applications/life-science-research/label-free-detection
Branche
Biotechnologieforschung
Größe
10.001+ Beschäftigte
Hauptsitz
Goettingen, Niedersachsen
Spezialgebiete
BioLayer Interferometry, Biomolecular Interaction Analysis, Binding Kinetics, Analytical Instrumentation, Affinity Assays, Concentration Assays, Antibody Quantitation, Protein Quantitation, Protein Characterization, Analyze Therapeutic Molecules, Large Molecule Research, Biophysical Characterization, Receptor-Ligand Binding, Titer Determination, Fragment Screening, Potency Assays, Host Cell Protein Detection, Residual Protein A Detection, Bioprocess Impurity Testing und IgG Titer

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