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Questions tagged [retrosynthesis]

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9 votes
3 answers
550 views

Synthesis of racemic nicotine

In my advanced organic chemistry course, we were asked to fill the following scheme for the synthesis of racemic nicotine, starting with ethyl nicotinate: Exercise 6: Complete the following scheme ...
Mäßige's user avatar
  • 383
6 votes
2 answers
1k views

Retrosynthesis of 4-ethyl-2,2,5,5-tetramethyl-1,3-dioxane

I asked a similar question yesterday. They ask us to suggest a retrosynthesis for 4-ethyl-2,2,5,5-tetramethyl-1,3-dioxane I found this slide in our lecture where a dioxane is synthesized. If I ...
wengen's user avatar
  • 423
5 votes
0 answers
120 views

Retrosynthesis of 2,5,8-trimethylnonan-5-ol

They ask us to suggest a retrosynthesis of 2,5,8-trimethylnonan-5-ol: So I went through my course slides, and I found this: Translation: verwende Grignard = use Grignard My question is: Can I ...
wengen's user avatar
  • 423
2 votes
0 answers
50 views

Palladium coupling reactions and purification

I tried to synthesize 2-(6-fluoropyridin-3-yl) acetic acid from 5-(Chloromethyl)-2-fluoropyridine using Pd(OAc)2/PPh3 catalyst,Na2CO3 and DCC. I eluted my product on TLC with Ethyl acetate/hexane/...
Ella's user avatar
  • 47