All Questions
Tagged with drugs chemical-biology
10
questions
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Drug dosage determination using dynamical systems
I am a Mathematical Biology student, and recently I have read about various approaches, such as Ordinary Differential Equations (ODEs), used to determine the exact drug dosage and treatment sessions ...
- 21
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1
answer
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What antimicrobial can be readily synthesized in a school laboratory for a project on antimicrobial resistance? [closed]
I am currently a student studying at a high school hoping to do a project on antimicrobial compound synthesis to use in investigating antimicrobial resistance in E. coli strains. I am hoping to ...
1
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1
answer
687
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How does Combinatorial Chemistry differ from Rational Drug Design?
I stumbled on Vertex Pharmaceuticals - Wikipedia.
It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry.
Then I looked up ...
user7952
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What is the composition, function, and classification of “6-Thio-2-Deoxyguanosine” and “13-mer thio-phosphoramidate”? How do I learn more about them?
I am assigned the task of explaining a biomedical research paper, it is about telomere and telomerase , and it talks a lot about the molecule Thio-2-Deoxyguanosine , 13-mer thio-phosphoramidate and &...
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How many natural products are there in existence? [closed]
Hi I'm doing a project on natural products and I'm wondering if somewhere there is at least an estimated number of how many exist?
If this exists somewhere can you please provide a reference.
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1
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1
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Modification to improve antibacterial activity
I have difficulties with part b).
For C, it's clear to make a bulky dimethoxybenzene group in order to block the C=O group from reacting with b-lactamase.
However, in A, how does the structure of ...
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2
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0
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291
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What is the most likely reaction between minocycline and tramadol in physiological conditions?
Minocyline (left) and Tramadol (right) are two commonly prescribed medications containing typical organic functional groups.
What would an expert chemist surmise as the first or most-likely reaction ...
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5
votes
2
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Why can curcumin cross the blood-brain barrier, but not congo red?
I've read that both congo red and curcumin are able to inhibit the clumping together of amyloid $\mathrm{β_{42}}$ in the brain, which would otherwise result in Alzheimer's disease.
Apparently, congo ...
- 18.8k
14
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3
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1k
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Is it possible to make a drug that liquefies heart plaque to treat heart disease?
Is it possible to make a drug that liquefies heart plaque to treat heart disease without damaging other parts of the body? If so, would the liquefied plaque be eliminated as regular fluid is through ...
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3
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How much hydrolysis will likely occur of the following bonds at pH 1-4 in the time period of 1-3 hours?
The bonds are: (I have given pictures of what I mean in case there's any ambiguity that I leave open in these questions. Also so that if you want to number the R groups you've got a head-start)
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