All Questions
Tagged with amines nitro-compounds
14
questions
5
votes
2
answers
1k
views
Can primary amine be produced using Grignard reagent?
I found a way to produce Secondary Alkyl Amines using Grignard Reagent.
(source: wiley.com)
Ref: Z. Huang, J. Lv, Y. Jia, Chemistry Select 2016, 1, 5892. DOI: 10.1002/slct.201601464
But I want to ...
- 71
0
votes
0
answers
39
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Preparation of m-nitroaniline from m-dinitrobenzene [duplicate]
Consulting various Organic Chemistry resources, I have found two reactions for the purpose stated in the subject:
First reaction:
Second reaction:
But, I cannot find the reaction mechanism by which ...
- 607
5
votes
3
answers
4k
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Selective reduction of nitro group to amine, in benzene ring containing nitrile?
I would like to know if there is a possible route of synthesis that may reduce 3-nitrobenzonitrile A to 3-aminobenzonitrile B.
I would normally reduce a nitro to an amine using $\ce{Pd/C}$ and $\ce{...
- 51
5
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2
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Nitration of aniline [duplicate]
(b) Nitration: Direct nitration of aniline yields tarry oxidation products in addition to the nitro derivatives. Moreover, in the strongly acidic medium, aniline is protonated to form the anilinium ...
- 103
0
votes
0
answers
914
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Why is the trimethylammonium group a stronger electron withdrawing group than the nitro group?
I was working on a question that basically boils down to deciding whether the nitro group ($\ce{-NO2}$) or the trimethylammonium group ($\ce{-N+(CH3)3}$) on a benzene ring, is a stronger electron ...
- 11
1
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0
answers
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Why is ethanol used in catalytic reduction of nitro group to an amine? [closed]
$$\ce{R-NO2 +C2H5OH + H2 (g)->[Pt/Pd/Ni] R-NH_2}$$
The above equation represents catalytic reduction of nitro group to amine. What is the role of ethanol in it?
I understand that $\ce{Pt/Pd/Ni}$ ...
- 219
3
votes
0
answers
821
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Selectivity of Zinin Reduction
What is it, that makes the Zinin Reduction a selective reduction, and not a complete reduction, in the case of dinitrobenzenes? Also, is the reaction a selective one even when it is done for aliphatic ...
- 333
1
vote
1
answer
4k
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Which occurs first: nitration or oxidation of aniline by concentrated nitric acid?
Which of the cases is possible or both or none?
- 1,232
3
votes
2
answers
5k
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How to transform an aliphatic primary amine to the corresponding nitro compound?
Could you suggest a reagent or procedure to transform an aliphatic primary amine to the corresponding nitro compound.
I know this is a bit backwards of a request because the usual procedure is the ...
31
votes
3
answers
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Selective nitro reduction of poly nitro compounds
Is there any way through which I could selectively reduce one $\ce{NO2}$ group from a dinitro- or trinitro- compound to an amine.
I was reading Solomons and Frhyle and it says that m-dinitrobenzene ...
- 3,805
6
votes
1
answer
918
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Amine addition to nitro group
What is the mechanisms of this reaction? How feasible is this reaction? Can it happen under relatively mild conditions if it is intermolecular?
- 14.4k
8
votes
1
answer
522
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Why are triamino compounds so rare?
I was doing a reaxys substructure search for the compound shown on the left below, with the 3 amines on 1 carbon. However, the closest I found were all trinitro compounds like on the right. I would ...
- 2,228
11
votes
3
answers
3k
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Reduction of α,β-unsaturated nitro compounds
Would it be possible to reduce a α,β-unsaturated nitro compound to a saturated amine using for example $\ce{NaBH4}$? I know these kind of compounds will be reduced by hydrogenation using a $\ce{Pt/C}$ ...
- 6,233
6
votes
1
answer
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Is 4-nitrobenzaldehyde or 4-aminobenzaldehyde more likely to be hydrated?
Of 4-nitrobenzaldehyde and 4-aminobenzaldehyde, which has the higher $\ce{K_{eq}}$ of hydration?
$\qquad \qquad$
Steric factors can likely be ignored in this problem since we are dealing with ...
- 19k