I need to Reduce the Nitrile group (CN) in the (3-cyanophenyl)boronic acid in to a primary amine without disturbing the Boronic acid group.Using LAH can trigger reduction of Boronic group. what are my options?
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$\begingroup$ Options : en.m.wikipedia.org/wiki/Nitrile_reduction $\endgroup$– DesaiCommented Jan 7, 2021 at 0:52
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2$\begingroup$ The answer and comments to this question are relevent chemistry.stackexchange.com/questions/74580/… $\endgroup$– WaylanderCommented Jan 7, 2021 at 8:00
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$\begingroup$ SmI2 looks a possibility Org. Lett., 2014, 16, 1092-1095. $\endgroup$– WaylanderCommented Jan 7, 2021 at 8:08
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$\begingroup$ Also could protect the boronate, perhaps with MIDA? $\endgroup$– AndrewCommented Jan 7, 2021 at 12:45
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