It is often stated that wider (performance) tires offer less rolling resistance at the same pressure (or less pressure at the same rolling resistance, which is beneficial for comfort). The well known Bike Rolling Resistance has published some comparatives on that: GP5000 Marathon (for reference, but the question is focused on performance/supple tires)
Given this fact is known, I noticed that bike/tires manufacturers only offer incremental increases in tire clearance on road bikes (gravel went from 40mm to 50mm clearance in a few years for instance, even if they rarely sold with the largest tires). But on the endurance road bike part of the spectrum, new models are sometimes limited to 35mm (the only exception I'm aware of is the Specialized Roubaix SL8, with 40mm clearance but sold 32mm tires).
So what would be the drawbacks of using wider tires on performance (endurance) road bikes, given they provide additional comfort for equivalent rolling resistance? (the focus is mostly on endurance, as for pure performance, the trade-off is often comfort against weight or rolling resistance).