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So I want to upgrade my PC's GPU. I saw that the GDDR generation was 5 (GDDR5), and I was wondering is the GDDR generation compatible with all motherboards.
My PC's specs: Motherboard: MSI Z87-G45 GAMING
CPU: Intel Core i7 [email protected] GHz
RAM: 16 GB Dual-Channel DDR3 @799MHz (soon 32 GB)

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It should not affect compatibility at all. Only thing I can think of would be a bottleneck scenario where PCI-E slot or other components cant keep up and even then it will work - just at a slower speed.

Edit. The parts you have listed should work just fine for most modern gaming.

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