You make a bat file script.
Here's how.
Make sure where the application is placed.
If the application is 64 bit "%programfiles%\<appfoldername>\<app>.exe"
If the application is 32 bit "%programfiles(x86)%\<appfoldername>\<app>.exe"
~HIGHDPIAWARE
Indicates value of Override high DPI scaling behavior (Application)
~DPIUNAWARE
Indicates value of Override high DPI scaling behavior (System)
"~GDIDPISCALING DPIUNAWARE"
Indicates value of Override high DPI scaling behavior (System Enhanced) add double quote also
I am doing this for Itunes (64 bit).
Particular User
REG ADD "HKCU\Software\Microsoft\Windows NT\CurrentVersion\AppCompatFlags\Layers" /V "%programfiles%\iTunes\iTunes.exe" /T REG_SZ /D ~HIGHDPIAWARE /F
All User
REG ADD "HKLM\Software\Microsoft\Windows NT\CurrentVersion\AppCompatFlags\Layers" /V "%programfiles%\iTunes\iTunes.exe" /T REG_SZ /D ~HIGHDPIAWARE /F