Template:1921 National League standings
| Team | W | L | Pct. | GB | Home | Road |
|---|---|---|---|---|---|---|
| New York Giants | 94 | 59 | .614 | — | 53–26 | 41–33 |
| Pittsburgh Pirates | 90 | 63 | .588 | 4 | 45–31 | 45–32 |
| St. Louis Cardinals | 87 | 66 | .569 | 7 | 48–29 | 39–37 |
| Boston Braves | 79 | 74 | .516 | 15 | 42–32 | 37–42 |
| Brooklyn Robins | 77 | 75 | .507 | 16½ | 41–37 | 36–38 |
| Cincinnati Reds | 70 | 83 | .458 | 24 | 40–36 | 30–47 |
| Chicago Cubs | 64 | 89 | .418 | 30 | 32–44 | 32–45 |
| Philadelphia Phillies | 51 | 103 | .331 | 43½ | 29–47 | 22–56 |