Novogene Europe’s Post

The Cedars-Sinai Accelerator programme has been game-changing for 52North - creators of Neutrocheck® on so many levels.   One really exciting development is our new collaboration with the state-of-the-art Tatonetti Lab. Prof Nicholas Tatonetti is Vice Chair of Operations in the Department of Computational Biomedicine and Associate Director of Computational Oncology in the Cancer Center at Cedars-Sinai . With buy-in from oncologists across Cedars-Sinai, and amazingly rich patient-level data from the hospital, we are kicking off a collaboration to develop and validate cutting-edge risk prediction models for cancer patients at risk of treatment-related complications, such as neutropenic sepsis.   👀 Watch this space!!!   And we strongly encourage any innovators looking for an accelerator program to take them to the next level, to apply for next year’s cohort.   Saif Ahmad Mireia Crispin KHP Ventures #52North #Neutrocheck #acceleratorprogram #omics #entrepreneurship #innovation #medicaltechnology #sepsisawareness #biomedicalengineering #healthcare #chemotherapy #biomedicalscience #datascience #computationalbiology #biomedicalresearch #bioinformatics *Credit for the photo to Cedars-Sinai.

Revolutionising cancer research: Bavarian researchers have discovered a new mechanism for improving immunotherapy 🔬 Scientists at Technische Universität München (Technical University of Munich) and Ludwig-Maximilians-Universität München have discovered a mechanism that influences how the immune system is undermined by tumours. These findings could make existing cancer immunotherapies significantly more effective. As a location, Bavaria offers immense opportunities in the fields of Health, MedTech and Life Sciences. 🚀 With over 350 biotechnology companies, a strong medical technology sector and renowned healthcare institutes, we create a unique climate for innovation and start-ups. International corporations such as Amgen, Roche and Novartis have settled here to benefit from the excellent research and networking with leading research institutions. The Bavarian life sciences ecosystem gives companies access to cutting-edge research and a large talent pool. Institutions such as the Max Planck Society and Helmholtz Munich also support innovative projects and promote international collaboration. 🌍 More about Health, MedTech and Life Sciences in Bavaria: https://lnkd.in/dyGe5qfQ BioM Biotech Cluster Development GmbH #successinbavaria #crossindustryinnovation #healthtech #lifescience

🛡️ Unraveling the Guardians of Genetic Secrets: The power of Extracellular Vesicles in miRNA protection The primary focus of Theramir Ltd’s project ‘’CompamiR’’ is the development of a novel diagnostic tool that promises to redefine early breast cancer detection. Our dedicated team is working towards harnessing the power of miRNA in blood, unlocking a new frontier in precision medicine🔍. MiRNAs hold great promise as biomarkers especially due to their remarkable stability in blood. But what is the secret of their stability?🤔 Circulating miRNAs are commonly released from cells within Extracellular vesicles|��Extracellular Vesicles (EVs) are derived from cells and play a vital role in facilitating cell-to-cell communication both locally and distantly. They have the potential to transfer various cargoes – including miRNAs– between cells. By encapsulating miRNAs within their lipid bilayers, EVs become guardians, safeguarding the integrity of these messengers throughout their journey. #CompamiR is funded by Ίδρυμα Έρευνας και Καινοτομίας/Research and Innovation Foundation under the category Young Researcher Culture Award (Coordinator: Dr Marianna Prokopi-Demetriades) in the field of Life Sciences. #ExtracellularVesicles #CellCommunication #miRNA #PrecisionMedicine #miRNA #Liquidbiopsy #innovation #miRNA #research #startup

Don’t Miss This! Dive into the future of biomedicine with us next week in #SanDiego! Join us next week at the Festival of Biologics San Diego for an interesting panel discussion brought to you by Business Location Switzerland and Swissnex in San Francisco. What’s on the Agenda?  We’re diving deep into RNA technology and its role in developing breakthrough antibody therapies to fight critical illnesses such as cancer, Alzheimer's, and autoimmune diseases. Get ready to explore the latest trends, groundbreaking research, and the challenges ahead with top experts from both #Switzerland and the #US. Meet Our Esteemed Panelists: - Rudi Micheletti, spearheading Biology and Functional Genomics at Haya Therapeutics. - Susan Szathmary, MD, PhD, leading the charge at the Open Biopharma Research and Training Institute. - Dimitrios G. Zisoulis, the mind behind RNA Therapeutics at Johnson & Johnson. - Gene Yeo, a pioneering Professor at UCSD’s Dept of Cellular and Molecular Medicine and a key figure at the UCSD Institute for Genomic Medicine. The panel discussion "Decoding the Dark Genome through RNA Technology: Ways Forward with Swiss and US Innovation’” will be moderated by the insightful Julio de Unamuno IV, Executive Director of HomeLab at UCSD. Don’t miss out on this opportunity to gain insights from leading minds in the field and discover how Swiss and US expertise is paving the way forward in biotech innovation. #biotechnology #RNAtechnology #innovation #whyswitzerland #FestivalofBiologics #healthcare #pharma

SOPHiA GENETICS’ VP, Multimodal R&D, Thierry Colin, will share his team's innovative work on multimodal research at ESTIA-Recherche tomorrow in Amphi 21 at ESTIA 2 campus, ESTIA Institute of technology. When a patient is diagnosed with cancer, they undergo numerous medical examinations (biopsy, imaging, biological, genomic analyses) so that doctors can propose a treatment plan. The decision regarding the type of treatment offered is made during a multidisciplinary consultation meeting (MCM) based on recommendations from various health agencies and/or professional societies. 💡 The results of the various medical examinations form a dataset whose richness is only partially exploited. In his presentation, Thierry will show how these data can be used to develop algorithms for personalized prediction of treatment response, focusing on localized kidney cancer and metastatic lung cancer. The talk will go beyond sharing our breakthroughs, and we look forward to sparking conversations. Thierry is eager to dive into discussions with ESTIA students, contributing to SOPHiA GENETICS's mission to nurture the next generation of talent right here in our local communities. #BasqueCountry #DataDrivenMedicine #FutureOfHealthcare

Congratulations to Dr Megan Mitchell Dr Olivier Loudig from the Center for Discovery and Innovation New Jersey, and to their colleagues, for the recent publication Exhaled breath condensate contains extracellular vesicles (EVs) that carry miRNA cargos of lung tissue origin that can be selectively purified and analyzed. This work presents an innovative approach for isolating EVs from exhaled aerosolized droplets and analyzing their content. By capturing the EVs, the scientists could intercept the "instant bio-messages" that cells use to communicate with one another in the lungs. They used several methods to assess the captured EVs, among them ONI's #EVProfiler kit, depicted in the attached image. This enabled them to not only identify the cells that generated the EVs, but also to carefully characterize the RNA molecules inside the EVs, and study them as diagnostic markers for various diseases, among them lung cancer. Read the full paper here: https://hubs.li/Q02vjXhf0 This paper is a fine example for the potential that EVs hold for the future of biomedical research. There is no doubt that EVs will play a major role in diagnostics and therapeutics, and we are very excited to see what new technologies are coming next. ONI scientists will attend #ISEV2024, where they will present our latest development in EV research, #EVProfiler2 with #AutoEV, as well as #AploFlow, our next generation end-to-end solution for EV capture, analysis and reporting. #Nanoimager #SuperResolution #microscopy #research #ExtraCellularVesicles #Biology #Biophysics #SingleMolecule #SMLM #dSTORM #LifeSciences #diagnostics

Are you ready to shed more light on your research? Look no further than the cutting-edge Celena X High Content Imaging System by Logos Biosystems.💡🧫🌟 The Celena X System is a groundbreaking solution designed to empower researchers and scientists with advanced imaging capabilities. Whether you're working in drug discovery, cell biology, or cancer research, this system offers unparalleled insights into cellular structures and functions. 🔹 High-resolution imaging for detailed analysis 🔹 Multiparametric data collection for comprehensive insights 🔹 User-friendly software for streamlined operation 🔹 Versatile applications, from 2D to 3D samples 🔹 Efficient automation for increased throughput 🔹 Accurate and reproducible results Ready to explore the future of imaging technology? Visit our website for detailed information about the Celena X High Content Imaging System. Elevate your research today!👇 https://lnkd.in/ePzhVzWR #BucherBiotec #LogosBiosystems #CelenaX #HighContentImaging #ResearchInnovation #biotechnology #ScientificDiscover

Telomeres are the protective nucleoprotein structures at the end of linear eukaryotic chromosomes. Telomeres’ repetitive nature and length have traditionally challenged the precise assessment of the composition and length of individual human telomeres. Here, we present Telo-seq to resolve bulk, chromosome arm-specific and allele-specific human telomere lengths using Oxford Nanopore Technologies’ native long-read sequencing. Telo-seq resolves telomere shortening in five population doubling increments and reveals intrasample, chromosome arm-specific, allele-specific telomere length heterogeneity. Telo-seq can reliably discriminate between telomerase- and ALT-positive cancer cell lines. Thus, Telo-seq is a novel tool to study telomere biology during development, ageing, and cancer at unprecedented resolution. Read publication➡️ https://lnkd.in/dRQpFa9u 🛒 Visit our webshop and unlock a world of possibilities ➡️ https://lnkd.in/eeMEMUTe Contact us today at whitesci@whitesci.co.za to talk to a specialist. #whiteheadscientific #webinar #nanopore #ngs #science #biotech

Whitehead Scientific Telomeres are the protective nucleoprotein structures at the end of linear eukaryotic chromosomes. Telomeres’ repetitive nature and length have traditionally challenged the precise assessment of the composition and length of individual human telomeres. Here, we present Telo-seq to resolve bulk, chromosome arm-specific and allele-specific human telomere lengths using Oxford Nanopore Technologies’ native long-read sequencing. Telo-seq resolves telomere shortening in five population doubling increments and reveals intrasample, chromosome arm-specific, allele-specific telomere length heterogeneity. Telo-seq can reliably discriminate between telomerase- and ALT-positive cancer cell lines. Thus, Telo-seq is a novel tool to study telomere biology during development, ageing, and cancer at unprecedented resolution. Read publication➡️ https://lnkd.in/dFb7JDep 🛒 Visit our webshop and unlock a world of possibilities ➡️ https://lnkd.in/eCtws8a8 Contact us today at whitesci@whitesci.co.za to talk to a specialist. #whiteheadscientific #webinar #nanopore #ngs #science #biotech

Let’s talk about everything bioinformatics, real-time analysis, and ultra-rich datasets on ONT platforms! Because #WYMM.