Novogene Europe’s Post

👀 Peek into Element Biosciences's AVITI at Garvan Institute of Medical Research – first site in the Southern Hemisphere. Many thanks go to all involved in planning, delivery, installation Mike Marshall Bobby Nasr and training Marty Flores.   🎯 This Out-of-the-box system has a dual flow cell design and individually addressable lanes, allowing the flexibility for operating two separate sequencing runs in one system.    🎯Together with Element’s proprietary avidity base chemistry (ABC), the AVITI enables exceptional accuracy (>90% >Q30) and reduced reagent consumption, delivering higher-quality data and more cost-effective sequencing options.   Learn more about AVITI – https://lnkd.in/gRf3sFiN   Check out our press release if you missed it – https://lnkd.in/gQez2bN6 #ngs #dnasequencing #AVITI #lifesciences #medicalresearch #australia #ElemBio #Genomics #Sequencing #ABCSequencing #ResearchInnovation #ShiftYourScience #rnaseq #biotechnology

Join us on 11th June at ACHEMA 2024 for our 𝗳𝗿𝗲𝗲-𝘁𝗼 𝗮𝘁𝘁𝗲𝗻𝗱 Drug Discovery Forum in Germany: ENHANCING THE QUALITY OF DATA IN CHEMICAL BIOLOGY AND TRANSLATIONAL SCIENCE Register here https://lnkd.in/eAJCVTTg The value and reliability of scientific data in biology and translational science is determined by the quality of chemical tools and their appropriate use. Well-characterised, selective small molecules are essential for understanding the cellular functions of proteins and validating them as drug targets. Conversely, the use of poorly evaluated molecules or the biased interpretation of data generated with promiscuous substances leads to pollution of the literature with unsubstantiated claims. The ELRIG Drug Discovery in Germany forum will focus on data quality generated with small molecules and present best practices and guidelines for the use, availability and characterisation of these tools using state-of-the-art methods. We will highlight examples with both traditional inhibitors and novel chemical modalities, such as PROTACs. The meeting will bring together approaches from industry and academia, working together to improve the reproducibility and robustness of scientific data, thereby advancing target validation and our understanding of target biology. #ACHEMA24 #ELRIG

The throughput of ion channel recordings increased to unprecedented levels with the use of #AutomatedPatchClamp. To make full use of such high-throughput #electrophysiology technology, academic labs have often pooled resources in a shared, core #APC facility. One of the earliest adopters of a core QPatch facility was The University of Queensland shared by the labs of Irina Vetter, Thomas Durek, Fernanda Cardoso & Glenn King. They have now published almost 50 #QPatch papers in the past decade and have been keeping the printing-presses busy in 2023 with a flurry of papers characterizing peptide #Toxins modulating sodium #IonChannels and the discovery of #TMEM233 – a new Nav1.7 accessory protein. These studies will provide further tool molecules and novel protein targets to understand and develop therapeutics for #ChronicPain.   Congratulations to all authors. Learn more and read the papers: https://lnkd.in/dkdXfH8f #Venoms #QPatch #AutomatedPatchClamp #IonChannels #DrugDiscovery #Electrophysiology #Sophion

If you're in the One Kendall Square, Cambridge area, don't miss our tabletop at the BVS event. Meet Jiyao (Ella) Zhang, our experienced PhD-level expert, and discover how iXCells products and services can support your research and discovery needs. #CellTechnology #GeneTherapy #CellTherapy #Innovation #DrugDiscovery #PersonalizedMedicine #RareDiseases #GeneEditing #EngineeredCells #CRISPRCas9 #CellModels #STEMCells #Biotechnology #LifeSciences #ResearchandDevelopment #motorneurons #immunecells #immunooncology #preclinicalservices #biotechevents

🤝After more than a year of collaboration with the Inflame team, we are delighted to share with you part of the work of Bastien Suire, PhD student co-supervised by Celine Cougoule (IPBS, CNRS-UT3) and Aurélie Gomes (IMACTIV-3D). His work on inflammasome activation reporter cells will enable us to offer a joint service, based on a high-throughput automated assay for the quantification of NLRP1 inflammasome activation/inhibition in human epithelial cells. The aim of this assay is threefold: 🧪1. Enable rapid, high-throughput selection of numerous candidate molecules for activation/inhibition of the NLRP1 pathway; 🧬 2. Determine which NLRP1 activation pathway acts on the molecule(s) under study, from a variety of known pathways; 🎯 3. Make this test widely available by offering a service to laboratories wishing to test candidate molecules for activation/inhibition of the NLRP1 pathway. ☎️ Please do not hesitate to contact us for further information. #Research #Inflammasome #BiomedicalResearch #PhDResearch #Biotech #CellBiology #Innovation #Healthcare #BiomedicalScience #DrugDiscovery #HighThroughput #FluorescenceMicroscopy #Imactiv3D

Here the latest from Outcome Capital's life sciences experts.

Grant Award Alert! We are thrilled to announce that GenNext Technologies has received a $2.5 million dollar grant from NIGMS to fund the development of advanced protein footprinting technology and products that support multiple labeling chemistries with companion real-time radical dosimetry and custom data processing software. This marks our twelfth SBIR award with aggregate funding in excess of $12 million dollars! Collaborating with the laboratories of Professors Michael Gross (Washington University in St. Louis) and Mark Chance (Case Western Reserve), our “Multi-Radical Protein Footprinting Platform (MRPF)” will extend radical labeling to challenging protein regions, such as the transmembrane domain of membrane protein targets, including G-protein coupled receptors. The company plans to introduce MRPF technology as future upgrades to its exclusive, first-in-class SamFox® and AutoFox® radical protein footprinting products. We are grateful to the National Institute of General Medical Sciences for its continued support and acknowledgement of our team’s effort to advance and facilitate structural biology research. We extend a big thank you to all who worked on this program for your relentless effort and innovation in advancing structural biology research: GenNext Team: Emily Chea, Jeff Persoff, Tan Bui, and Robert Egan; WUSTL Team: Michael Gross and Prashant Jethva; CWRU Team: Mark Chance, Janna Kiselar, and Rohit Jain. #GenNext #Research #Science #ScientificResearch #Biotherapeutics #ProteinCharacterization #ResearchInnovation #HRPF #ProteinResearch #ScientificInnovation #Teamwork #ProteinStructure #StructuralBiology #Biochemistry #Proteomics #Biotechnology #Antibody #mAb

Grant Award Alert! We are thrilled to announce that GenNext Technologies has received a $2.5 million dollar grant from NIGMS to fund the development of advanced protein footprinting technology and products that support multiple labeling chemistries with companion real-time radical dosimetry and custom data processing software. This marks our twelfth SBIR award with aggregate funding in excess of $12 million dollars! Collaborating with the laboratories of Professors Michael Gross (Washington University in St. Louis) and Mark Chance (Case Western Reserve), our “Multi-Radical Protein Footprinting Platform (MRPF)” will extend radical labeling to challenging protein regions, such as the transmembrane domain of membrane protein targets, including G-protein coupled receptors. The company plans to introduce MRPF technology as future upgrades to its exclusive, first-in-class SamFox® and AutoFox® radical protein footprinting products. We are grateful to the National Institute of General Medical Sciences for its continued support and acknowledgement of our team’s effort to advance and facilitate structural biology research. We extend a big thank you to all who worked on this program for your relentless effort and innovation in advancing structural biology research: GenNext Team: Emily Chea, Jeff Persoff, Tan Bui, and Robert Egan; WUSTL Team: Michael Gross and Prashant Jethva; CWRU Team: Mark Chance, Janna Kiselar, and Rohit Jain. #GenNext #Research #Science #ScientificResearch #Biotherapeutics #ProteinCharacterization #ResearchInnovation #HRPF #ProteinResearch #ScientificInnovation #Teamwork #ProteinStructure #StructuralBiology #Biochemistry #Proteomics #Biotechnology #Antibody #mAb

o2h discovery's commitment to excellence in scientific research is exemplified by our recent investment in the FLIPR Penta technology. We stand ready to collaborate seeking FLIPR-based assay services for different drug discovery programs. The introduction of the FLIPR Penta High-Throughput Cellular Screening System to our repertoire, enables rapid screening of compound libraries and to assess the effects of potential drug candidates in a fast, automated, and precise manner. It has extensive use in understanding GPCR and ion channel biology. With the simultaneous pipette and read function, plus high-end camera system, we can allow up to 100 measurements per second and provide detailed information about cardiomyocyte and/or neuronal  oscillations. We offer multiple fluorescence or luminescence-based assay readouts, and can support in measuring calcium flux, potassium and membrane potential. To know more about our biology service please visit - https://lnkd.in/dFQdm2z6 or write us at discovery@o2h.com Partner and speak with our biologists to tailor your research needs, and let us contribute to the advancement of your drug discovery initiatives. #o2hdiscovery #BiologyCapabilities #DrugDiscovery #BiologyServices #SeedingNewIdeas #LifeScience #Biotech #GPCR #ionchannels #assaydevelopment #research #biology

🌟 Empowering Life Science Research: Sino Biological, Inc. & Bioz 🌟 🔬 Sino Biological's Commitment Sino Biological is dedicated to delivering high-quality recombinant proteins, antibodies, cDNA clones, and ELISA Kits. Their focus? Being a one-stop technical service hub for researchers worldwide. At Bioz, we're excited to spotlight our collaboration with Sino Biological - a leader in providing top-tier reagents and services for life science researchers globally. 🚀 Bioz's Impact With Bioz Badges integrated on Sino Biological’s platform: -Enhanced Visibility: Researchers can instantly see trusted, AI-curated citations for Sino Biological's products. -Increased Credibility: Real-time data insights bolster the reliability of their extensive reagent offerings. -Streamlined Discovery: Making it easier for scientists to find and trust the reagents they need. 🤝 Together, Bioz and Sino Biological are driving forward scientific discovery and innovation. It’s a partnership where quality meets credibility! #BiozBadges #SinoBiological #LifeScienceInnovation #Bioz