MUVON Therapeutics AG’s Post

Portfolio News of InnoSource Ventures AG: We are proud of the team of RedDress Ltd. Revolutionizing Nerve Regeneration In a recent feature in the Bioengineering Journal, RedDress Ltd. showcased a remarkable breakthrough in nerve regeneration. By combining their unique whole blood clot technology with a nerve conduit, they've achieved unprecedented success in regrowing axons, offering new hope for patients with significant nerve loss. Additionally, their research shows promise in treating complex anal fistulas, offering hope for Crohn's and IBD patients. @Reddress's ActiGraft solution is also making waves in wound care, saving limbs and changing lives for diabetic patients. Explore the research here: https://lnkd.in/dAxitgkJ #Innovation #HealthCare #WoundCare #HealthCare #HealthTech #MedTech #Crohn #IBD

We are excited to share that Rayscape Lung CT is now available on Prof. Gerd Schueller's Radailogy! Rayscape Lung CT offers a comprehensive set of features, including:    ➡️Identification of solid, sub-solid, and ground-glass pulmonary nodules with a diameter ranging from 3 to 30 mm ➡️Precise highlighting of nodule presence on each slice ➡️Display of lobar locations for identified nodules ➡️Automatic measurement of nodule diameter and volume ➡️Assignment of attributes to each nodul ➡️Comparative analysis of lung nodule characteristics across follow-up investigations ➡️Inclusion of Fleischner Society recommendations for nodule follow-up for each analyzed CT scan #Lungnodules #AIforCT #AIforpulmonarynodules #ndulesdetection #lungcancer

Ich freue mich auf #resiconference 2024 in Barcelona am 17th Juni, Investoren und Unternehmen aus dem Bereich Diagnostik kennenzulernen. Übrigens: was haben Pathologie und Diagnostik gemeinsam? Here you go:

𝐃𝐨 𝐲𝐨𝐮 𝐤𝐧𝐨𝐰 𝐰𝐡𝐚𝐭 𝐢𝐬 𝐭𝐫𝐢𝐜𝐤𝐲 𝐢𝐧 𝐝𝐞𝐭𝐞𝐜𝐭𝐢𝐧𝐠 𝐜𝐚𝐫𝐝𝐢𝐚𝐜 𝐝𝐢𝐬𝐞𝐚𝐬𝐞𝐬?💓   In medical practice, getting an accurate diagnosis is super important but poses a big challenge. It's like the starting point for deciding what to do next. But here's the thing: doctors often have to deal with probabilities instead of certainties, which can be tricky.   🩺 𝐁𝐚𝐲𝐞𝐬' 𝐓𝐡𝐞𝐨𝐫𝐞𝐦 is a mathematical concept that helps doctors guide clinical decision-making, after a test result is available. It explains, why a 𝑝𝑜𝑠𝑖𝑡𝑖𝑣𝑒 𝑡𝑒𝑠𝑡 𝑟𝑒𝑠𝑢𝑙𝑡 is more likely to be accurate (true positive) when found in a group with a high disease prevalence. Conversely, in a group with a low disease prevalence, it's prone to be a false alarm (false positive). 📈 𝐋𝐞𝐭'𝐬 𝐚𝐭𝐭𝐞𝐦𝐩𝐭 𝐭𝐨 𝐠𝐫𝐚𝐬𝐩 𝐭𝐡𝐢𝐬 𝐜𝐨𝐧𝐜𝐞𝐩𝐭 𝐰𝐢𝐭𝐡 𝐚 𝐬𝐢𝐦𝐩𝐥𝐞 𝐚𝐧𝐚𝐥𝐨𝐠𝐲: Picture you spot a bald man randomly on the street, and your mind wanders about his probability of having cancer. What would your initial guess be? Now, the scenario shifts, and you find yourself in a hospital, encountering the same bald man. When you see a bald man in a hospital setting, your intuition tends to incline toward a higher probability, doesn't it? 😉   This highlights the importance of considering pre-test probabilities when interpreting medical test results.   Discover in this article published by Dr. Thomas M. Helms, Prof. Christian A. Perings und Prof. B. Andrew Remppis in Cardio News, why accurately assessing the pre-test probability is crucial in diagnosing coronary artery disease (#CAD) and how 𝐂𝐚𝐫𝐝𝐢𝐨 𝐄𝐱𝐩𝐥𝐨𝐫𝐞𝐫®improves the patient journey. https://lnkd.in/eGtZ5iGd Exploris Health AG offers through Cardio Explorer® the only precise, simple, and reliable diagnostic test, that can improve the diagnostic pathway through precise assessment of the pre-test probability, ensuring patients at risk are identified early, while at the same time ensuring the reduction of false positive results and avoiding unnecessary and costly procedures.   🚀💓 #Innovation #Heart 📚💡 #AI #Startups #MedicalScience

Cutting-edge sensors to detect transplant rejection! For those who receive the gift of an organ transplant, the fear of rejection is an ongoing and haunting concern. But now, researchers at Northwestern University have unveiled a sensor that offers early warnings of potential rejection. This sensor is a thin, flexible marvel that adheres to the surface of the transplanted organ. What's remarkable is that it can detect even a minor increase in organ temperature, which could be an early sign of rejection. Once detected, it wirelessly communicates with clinicians via Bluetooth. Preliminary tests conducted on rodents with kidney transplants yielded astonishing results. This innovation promises to transform the lives of transplant recipients. Bob Hackney Mike McSherry Kevin P. McRaith Chad Moore Blanca Lesmes Michael Evers #OrganTransplants #MedicalInnovation #EarlyWarningSystem #HealthcareBreakthrough

Almost 35 million people in the United States struggle with diabetes. All are at risk of permanently losing their vision from diabetic retinopathy(DR), a complication that can damage eyesight if it isn't caught soon enough. There is a need for an efficient and accurate way to diagnose DR before it can rob patients of their eyesight. Summit Venture Studio is currently analyzing a computer aided diagnosis system for detecting early warning signs of diabetic retinopathy, catching it before it can cause permanent damage, and we are looking for help validating this technology. What are some of the roadblocks of taking this technology to market? Is there any existing tech that is already doing this? Any subject matter expertise would be helpful! Looking to speak with ophthalmologists, and endocrinologists. Midday Connect, Taylor Bench, Spencer Walker

Over 650 million people globally suffer from this debilitating joint condition, yet we've had precious few treatment options. But findings from an International Space Station study just cracked the code on an innovative tissue model—one that accurately replicates the onset of post-traumatic osteoarthritis. This "tissue chip" fast-forwards the disease's progression in a carefully controlled environment by simulating accelerated bone loss from microgravity. The implications are massive—researchers can now study osteoarthritis mechanisms with stunning precision, test potential drug interventions, and do the whole nine yards. The initial results seem incredibly promising. The model precisely mimicked how current anti-inflammatory medications impact real patients. But more exciting? It revealed growth-stimulating treatments that could repair damaged cartilage—a total game-changer for an arena that's been maddeningly stagnant. This is a great and tangible example of how we see a rapid change of accepted norms in a specific area of study, generating new ideas and an outside-the-box approach to advancing a field. However, it also raises many questions about the regulation, restriction, and evaluation that need to be involved when taking a completely new approach to tackling a problem that hasn't been done before. This is a great parallel to so many different areas where the game has changed and new, higher-order problem-solving is becoming commonplace. Given the breakthrough potential, do you think more funding should be funnelled into this orbital research? Or do you foresee any concerning ethical pitfalls here?

auricular Vagus Nerve Stimulation (aVNS) in the treatment of #chronicpain. Recently, a position paper from the Austrian Pain Society/Österreichische Schmerzgesellschaft on “Goals in the Treatment of Chronic Pain”/"Ziele in der Behandlung chronischer Schmerzen" was published. Chronic pain is discussed within a bio-psycho-social pain model, highlighting the complexitiy of this disease. Diagnosis, therapeutic goals and guideline-compliant interdisciplinary, multimodal pain therapy - as the therapeutic approach with the highest evidence today - are discussed. The position paper also addresses how auricular #vagusnerve stimulation can be utilized effectively and safely as one component of multimodal pain therapy, e.g., in chronic low back pain, cervical syndrome, migraine, or acute post-surgery pain. Find the publication here (in German): https://lnkd.in/dMbbSkSS Find more on our approach on our website: https://aurimod.com/en/ #neuromodulation #painmanagement #chronicpain #vagusnerve #guidelines https://lnkd.in/dMbbSkSS

Leukocyte- and Platelet-Rich Fibrin: A New Method for Scalp Defect Reconstruction. Conclusion: This study showed that the use of L-PRF in the re-construction of scalp defects seem to be an effective method for scalp coverage in patients with small-to-large defects, even when the L-PRF is placed on the external table of calvarium without vascularized base. L-PRF is superior to other reconstruction techniques because it can be performed in the outpatient setting, in a single procedure together with resection and is overall available and inexpensive. The major disadvantages include frequent and more follow-upsfor larger defects and poor aesthetic results in hairy scalps. Constantinus Politis, MD, DDS, MM, MHA, PhD*Yannick Spaey, MD, DDS* Van Cleemput, MD, DDS*†Sylvie Hendrikx, MD, DDS†,