Meet ESM3, the state-of-the-art language model transforming how we understand and engineer proteins. Curious about how AI can achieve unprecedented accuracy in predicting and designing proteins? ESM3 leverages advanced AI techniques like bi-directional transformers and geometric attention to unify protein sequence generation, structure prediction, and function prediction. The impact is significant: ESM3's precision in predicting protein structures and functions is revolutionizing biomedical research. It's accelerating drug development, enabling precise protein engineering, and uncovering new biotechnological applications. ๐งช A highlight of ESM3's capabilities is its ability to generate novel proteins, such as esmGFP, a fluorescent protein unlike any found in nature. This showcases ESM3's innovative power in designing functional biomolecules. Join us in exploring the future of protein modeling with ESM3! Stay tuned for our upcoming blog post detailing how this technology is reshaping the biotech landscape. https://hubs.ly/Q02DpGlY0 #ProteinModeling #AIResearch #Biotechnology #ESM3 #ComputationalBiology
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Wow - 2 ex-Meta employees launch EvolutionaryScale landing $142m to advance AI in biology. EvolutionaryScale has introduced ESM3, a cutting-edge language model for biology that predicts protein sequences, structures, and functions. This model can simulate millions of years of evolution, generating new proteins with potential applications in medicine, research, and sustainability. ESM3 represents a significant advancement in AI's ability to design and engineer biological systems. There will be comparisons with AlphaFold3, intrigued where this goes... https://lnkd.in/dhtQDtsA #AIinDrugDiscovery #genomics #proteomics
ESM3: Simulating 500 million years of evolution with a language model
evolutionaryscale.ai
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When is AI alone adequate for answering scientific questions? It depends. A multi-institutional team led by Paul Adams at Berkeley Lab and Tom Terwilliger at the New Mexico Consortium found that AI-based protein structure predictions are best considered to be exceptionally useful hypotheses. As good as they are, experimental measurements remain essential when confirming the details of protein structures. #BioMBIB #artificialintelligence #proteinstructure https://lnkd.in/gTdrSNst
Researchers Assess AlphaFold Model Accuracy - Biosciences Area
https://biosciences.lbl.gov
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"Discover how DiffPALM, an AI-based approach by EPFL scientists, revolutionizes protein sequence prediction, offering new insights for drug development and disease treatment in computational biology. #AI #ProteinPrediction #DrugDevelopment"
Cutting-edge AI pairs proteins for optimal interaction.
https://airwaveai.com
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Creativity is as important as knowledge / Director, Center for Genetics and Genomics / Director, Ph.D. Program in Sciences and Innovation in Medicine at Universidad del Desarrollo
Chroma: a new AI tool that creates proteins and protein complexes not found in nature with programmable properties for therapeutic potential Chroma works at the intersection of machine learning, biological engineering, and medicine, emphasizing protein design. It enables protein design through Bayesian inference. Experimental characterization demonstrates that proteins designed by Chroma are highly expressed, fold correctly, and have favorable biophysical properties. This approach to protein design holds promise for accelerating the programming of protein matter for applications in human health, materials science, and synthetic biology. The original article was published in Nature: https://lnkd.in/eAv9ZMWh. https://lnkd.in/eXfEdw7S #genetics #genomics #precisionmedicine #genomicmedicine #ai #proteomics #proteins ##machinelearning #bioengineering #medicine #drugdesign #drugdevelopment #design #health #materialsscience #syntheticbiology #therapeutics #biotechnology #innovation #research #science #sciencecommunication
New Generative AI Model Designs Proteins Not Found in Nature
genengnews.com
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Protein Purification Department Head at Merck KGaA. Publish about Cutting-Edge Protein Design and Purification, Exciting Bioscience Career Opportunities, and Ethical Frontiers in Pharmaceutical Innovation!
Chroma is fueling innovation in life sciences! ๐ Imagine a future where protein tools and enzymes drive our research to unprecedented heights. ๐งฌ Let's break free from the norm, identify challenges in current workflows, and pave the way for a new era. Are you facing hurdles with work complexity or tool stability? Share your insights in the comments, and let's envision a protein-powered revolution together! ๐ช๐ฌ #ProteinTools #EnzymeInnovation #LifeScienceFuture" #Chroma
Creativity is as important as knowledge / Director, Center for Genetics and Genomics / Director, Ph.D. Program in Sciences and Innovation in Medicine at Universidad del Desarrollo
Chroma: a new AI tool that creates proteins and protein complexes not found in nature with programmable properties for therapeutic potential Chroma works at the intersection of machine learning, biological engineering, and medicine, emphasizing protein design. It enables protein design through Bayesian inference. Experimental characterization demonstrates that proteins designed by Chroma are highly expressed, fold correctly, and have favorable biophysical properties. This approach to protein design holds promise for accelerating the programming of protein matter for applications in human health, materials science, and synthetic biology. The original article was published in Nature: https://lnkd.in/eAv9ZMWh. https://lnkd.in/eXfEdw7S #genetics #genomics #precisionmedicine #genomicmedicine #ai #proteomics #proteins ##machinelearning #bioengineering #medicine #drugdesign #drugdevelopment #design #health #materialsscience #syntheticbiology #therapeutics #biotechnology #innovation #research #science #sciencecommunication
New Generative AI Model Designs Proteins Not Found in Nature
genengnews.com
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Synthetic Biology Market : Use of Machine Learning in research and development In recent years, artificial intelligence (AI)/machine learning has emerged as a plausible alternative to systems biology for the elucidation of biological phenomena and in attaining specified design objective in synthetic biology. The current development of artificial intelligence (AI) and machine learning (ML) techniques and tools in the biological and biotechnological domains can be viewed similarly for bringing about smarter and more automated analysis and decision-making to these fields. Read More | Download PDF Brochure Now :- https://lnkd.in/dd8-bfVE AI/ML remains an alternative for investigating system behaviors and improving the output of interest in synthetic biology applications. Currently various market players shifted the focus on machine learning use in synthetic biology. Additionally, immensive government support This is likely to create lucrative growth opportunities in coming years. For instance, as of November 2022, BigHat Biosciences, Inc., a biotechnology company with a machine learning-guided antibody discovery and development platform entered in collaboration with Merck to develop AI-enabled platform to expedite protein engineering to design and develop novel therapeutic candidates. Under the collaboration, BigHat and Merck will collaborate to optimize up to three proteins by leveraging BigHatโs platform to synthesize, express, purify, and characterize molecules. The size of global synthetic biology market in terms of revenue was estimated to be worth $11.4 billion in 2022 and is poised to reach $35.7 billion by 2027, growing at a CAGR of 25.6% #syntheticbiology #biotechnology #bioengineering #geneticengineering #genomeediting #crispr #syntheticgenomics #lifesciences #biotechindustry #molecularbiology
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We are thrilled to announce the release of ๐ฎ GenPro2 โ A generative AI protein discovery and analysis tool utilizing ESMFold/EMS-2 model by META AI and the Protein Data Bank(PDB). Protein folding is revolutionizing life science, unlocking the magic of life's molecular machinery, and propelling us into a new era of medical and technological breakthroughs! This groundbreaking advancement promises to accelerate drug discovery, combat diseases, and engineer unprecedented innovations in biotechnology. You can access it now on Hugging Face by visiting: WANDS (dot) AI No need for prior molecular biology knowledge (although it does help). Dive in and start discovering novel proteins using natural language seed words! --------------- #OpenScience #OpenSource #LifeScience #ProteinFolding #ESMFold #AlphaFold
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Wow, the advancements in the field of Structural Biology are truly remarkable! The integration of machine learning algorithms, particularly AlphaFold, has undoubtedly revolutionized protein structure prediction. It's amazing to think that in just two years, AlphaFold has predicted the structures of almost every known protein. Not only does this have significant implications for protein study, but it also has the potential to reshape various sectors. From expediting drug discovery and improving disease diagnosis to driving innovation in materials science, the impact is far-reaching.....
Founder | Data Science Wizard | Author | Forbes Next 1000 | Global talent awardee | APAC Entrepreneur of the year
๐งฌ๐ป the Power of AI in Biomedical Science! The field of ๐๐ญ๐ซ๐ฎ๐๐ญ๐ฎ๐ซ๐๐ฅ ๐๐ข๐จ๐ฅ๐จ๐ ๐ฒ, pivotal in understanding protein structures, has witnessed a monumental leap forward, thanks to machine learning algorithms. Traditionally, uncovering protein structures - crucial as their functions rely on their shapes - has been a slow process. Out of an estimated 100 to 200 million proteins, less than 1% have been explored by humans. Enter AI's game-changing role. In a mere two years, the AI system ๐๐ฅ๐ฉ๐ก๐๐ ๐จ๐ฅ๐ has astoundingly predicted the structures of almost every protein known to us, now accessible in an open online database. This isn't just a win for protein study. AlphaFold's contributions are reshaping entire sectors, from accelerating ๐๐ซ๐ฎ๐ ๐๐ข๐ฌ๐๐จ๐ฏ๐๐ซ๐ฒ and refining ๐๐ข๐ฌ๐๐๐ฌ๐ ๐๐ข๐๐ ๐ง๐จ๐ฌ๐ข๐ฌ to innovating in ๐ฆ๐๐ญ๐๐ซ๐ข๐๐ฅ๐ฌ ๐ฌ๐๐ข๐๐ง๐๐. For a deeper dive, check out 'Incorporating Machine Learning into Established Bioinformatics Frameworks'. The paper's insights are linked in the comments. #machinelearning #bioinformatics #alphafold #healthtech #innovation
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๐งฌ๐ป the Power of AI in Biomedical Science! The field of ๐๐ญ๐ซ๐ฎ๐๐ญ๐ฎ๐ซ๐๐ฅ ๐๐ข๐จ๐ฅ๐จ๐ ๐ฒ, pivotal in understanding protein structures, has witnessed a monumental leap forward, thanks to machine learning algorithms. Traditionally, uncovering protein structures - crucial as their functions rely on their shapes - has been a slow process. Out of an estimated 100 to 200 million proteins, less than 1% have been explored by humans. Enter AI's game-changing role. In a mere two years, the AI system ๐๐ฅ๐ฉ๐ก๐๐ ๐จ๐ฅ๐ has astoundingly predicted the structures of almost every protein known to us, now accessible in an open online database. This isn't just a win for protein study. AlphaFold's contributions are reshaping entire sectors, from accelerating ๐๐ซ๐ฎ๐ ๐๐ข๐ฌ๐๐จ๐ฏ๐๐ซ๐ฒ and refining ๐๐ข๐ฌ๐๐๐ฌ๐ ๐๐ข๐๐ ๐ง๐จ๐ฌ๐ข๐ฌ to innovating in ๐ฆ๐๐ญ๐๐ซ๐ข๐๐ฅ๐ฌ ๐ฌ๐๐ข๐๐ง๐๐. For a deeper dive, check out 'Incorporating Machine Learning into Established Bioinformatics Frameworks'. The paper's insights are linked in the comments. #machinelearning #bioinformatics #alphafold #healthtech #innovation
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Founder | Data Science Wizard | Author | Forbes Next 1000 | Global talent awardee | APAC Entrepreneur of the year
๐งฌ๐ป the Power of AI in Biomedical Science! The field of ๐๐ญ๐ซ๐ฎ๐๐ญ๐ฎ๐ซ๐๐ฅ ๐๐ข๐จ๐ฅ๐จ๐ ๐ฒ, pivotal in understanding protein structures, has witnessed a monumental leap forward, thanks to machine learning algorithms. Traditionally, uncovering protein structures - crucial as their functions rely on their shapes - has been a slow process. Out of an estimated 100 to 200 million proteins, less than 1% have been explored by humans. Enter AI's game-changing role. In a mere two years, the AI system ๐๐ฅ๐ฉ๐ก๐๐ ๐จ๐ฅ๐ has astoundingly predicted the structures of almost every protein known to us, now accessible in an open online database. This isn't just a win for protein study. AlphaFold's contributions are reshaping entire sectors, from accelerating ๐๐ซ๐ฎ๐ ๐๐ข๐ฌ๐๐จ๐ฏ๐๐ซ๐ฒ and refining ๐๐ข๐ฌ๐๐๐ฌ๐ ๐๐ข๐๐ ๐ง๐จ๐ฌ๐ข๐ฌ to innovating in ๐ฆ๐๐ญ๐๐ซ๐ข๐๐ฅ๐ฌ ๐ฌ๐๐ข๐๐ง๐๐. For a deeper dive, check out 'Incorporating Machine Learning into Established Bioinformatics Frameworks'. The paper's insights are linked in the comments. #machinelearning #bioinformatics #alphafold #healthtech #innovation
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