MEGIN’s Post

Whole brain imaging of neuroinflammation (blue) and vasculature (red and yellow) in response to stroke. https://lnkd.in/euzPbd9v   This awesome staining was done by Lea Lydolph and is part of an excellent collaboration with Kate Lykke Lambertsen.   #cns #neuroscience #brain #stroke #neurodegeneration #cro #preclinical #preclinicalresearch Gubra #neuroinflammation #spatialbiology  

A well designed! Whole brain imaging of Neuroinflammation (blue) and vasculature (red and yellow) in response to stroke.

I wanted to share some of our latest work. Using a central median nucleus for patients with multifocal refractory epilepsy, we employed a configuration with a 10mm anterior microelectrode and a 3mm central macroelectrode. In the upper region of the recording, some thalamic beta waves can be observed, which become more evident if the patient has a BIS (Bispectral Index) below 40. Between the ViM (ventral intermediate nucleus) and the CeM (central median nucleus), some high-frequency firing can be found, and then near the target, there is either silence or some Bursting Cells. An anterior macroelectrode stimulus is applied to verify that we are in the correct position, as this stimulus activates ascending fibers of Vc (ventral caudal nucleus) if correctly placed. Does this process help with the disease? Below, I leave the preliminary results paragraph for 11 patients. We will soon have a publication with many more patients. #Microrecording #DBS #Centromedian #Refractoryepilepsy #Neuroscience #Neurophysiology for more info: https://lnkd.in/eicuWbbw

📢Special Issue Deadline is Extended! 👉Advanced Studies of the Neuron Model of Neurodegenerative Diseases edited by Prof. Dr. Antonella Cardinale and Dr. Antonio De Iure 👉http://mdpi.com/si/161977 📅New deadline: 12 April 2024 👉Check all Special Issues open in "Neurodegenerative Diseases" section: https://lnkd.in/dZS7SVkV MDPI Scilit #neuroscience #brain #neuron #NeurodegenerativeDisease #InVitroModels #TransDifferentiatedNeurons

Two-photon microscope stacks from Hippocampus CA1 during first postnatal week with calcium indicators, activity dependent development… . #biology #neuroscience #hippocampus #neuron #neurons #physiology #brain #microscope

Whole brain imaging with single cell resolution. Find out how quantitative Light Sheet Fluorescence Microscopy (LSFM) can be used to study neurodegenerative diseases such as Parkinson's and Alzheimer's: https://lnkd.in/euzPbd9v Gubra #preclinicalresearch #preclinical #neuroscience #neurodegenerativediseases #neurodegeneration #cns #parkinsonsdisease #alzheimersdisease #alzheimers #parkinsonsresearch #alzheimersresearch

We’ve got a jam-packed schedule of presentations, panel debates and workshops at next week’s INS World Congress. From discussions around Innovations in Neuromodulation, to the use of big data in spinal cord stimulation, here's a sneak peak of the topics we’ll be covering off at the event next week. We look forward to seeing you there! #INS2024 #Neuromodulation #VisitVancouver #neuroscience #NevroHFX #HFXBigData #RealWorldOutcomes #ChronicPain #HFXAlgorithm #spinalcordstimulation 

Our new model of synaptic transmission based on fractional Brownian motion of vesicles has been published in The Journal of Physiology Find out more -> https://shorturl.at/ehxHV #physiology #neuroscience #synapse #brain

One of the first major objectives in my Ph.D has been accomplished: My team has received approval from the Medical Research Ethics Committee (VMK) to start the process of recruiting participants for testing two new ultrasound methods for the carotids, developed in collaboration with the Technical University of Denmark. The two methods should make it possible to conduct pressure- and flow estimation in the carotid arteries. Our aim is to improve our diagnostic and understanding of carotid stenosis; which is major cause of stroke. You can find out more about the methods in these articles: “A New Method for Noninvasive Pressure Gradient Estimation in the Carotid Using Ultrasound" and “Quantifying the Accuracy of 3-D Tensor Velocity Imaging Using Row-Column Addressed Arrays on a Carotid Bifurcation Model". #Neurosonology #Ultrasound #Neuroimaging #Stroke https://lnkd.in/eSKjqcmG https://lnkd.in/eKsPWrwv

📢 All submissions in the Special Issue "Modern Bioelectromagnetism Methods for Optimizing Diagnosis and Therapy in Epilepsy" have been published! 👩🎓Guest Editors👨🎓: 🎓Prof. Dr. Carsten Wolters 🎓Dr. Stefan Rampp 🎓Dr. Elaine Foley 🎆Enjoy reading: http://mdpi.com/si/58467 👉Check all Special Issues open in "Neurotechnology and Neuroimaging" section: https://lnkd.in/dSg88Frs MDPI Scilit #neuroscience #brain #EEG #MEG #electroencephalography #magnetoencephalography #BrainImaging #neuroimaging #epilepsy #EpilepsyTreatment